Cep290 (NM_146009) Mouse Tagged ORF Clone

Specifications

Product Data
Type	Mouse Tagged ORF Clone
Tag	Myc-DDK
Synonyms	b2b1454Clo; b2b1752Clo; BC004690; Nphp6
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >MR222042 representing NM_146009 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCACCTAATATAAAGTGGAAAGAATTAATCAAAGTTGATCCAGATGACCTGCCACGGCAAGAAGAGT TAGCAGATAAATTATTGATATCTTTATCCAAGGTGGAAGTAAATGAACTAAAAAATGAAGACCAAGAAAA CATGATACATCTATTCAGAATTACCCAGTCTCTAATGAAGATGAAAGCCCAGGAAGTAGAGCTCGCTTTG GAAGAAGTTGAAAAGGCTGGAGAAGAACAAGCAAAATTTGAAAATCAATTAAAGACAAAAGTAATGAAAC TGGAAAATGAACTGGAGATGGCTCAGCAGTCTGCAGGGGGACGTGACACTCGGTTTTTACGTGACGAAAT TCGCCAACTTGAGAAGCAGCTGGAACAAAAAGATAGAGAATTAGAGGATATGGAAAAAGAATTGGATAAA GAAAAGAAGGTTAATGAACAATTGGCTCTTCGAAATGAGGAGGCAGAAAATGAAAACAGCAAATTAAGAA GAGAGAACAAACGTCTAAAGAAAAAGAATGAGCAGCTTCGGCAGGACATTATTGACTACCAGAAACAAAT AGATTCACAGAAAGAATCACTTCTGTCAAGGAGAGGAGAAGACAGTGACTACCGATCACAGTTGTCTAAA AAGAACTATGAACTTGTTCAATATCTGGACGAAATACAGACCTTAACAGAAGCTAATGAGAAGATTGAAG TTCAGAACCAAGAAATGAGGAAAAACCTGGAAGAGTCTGTGCAGGAGATGGAGAAGATGACTGATGAGTA CAACAGGATGAAAGCGCTTGTGCATCAGTCGGATGCTGTCATGGACCAGATCAAGAAGGAGAATGAGCAC TATCGCCTGCAAGTTCGAGAGCTCACGGATCTTCTGAAGGCGAAGGATGAAGAGGACGATCCAGTCATGA TGGCTGTTAACGCAAAAGTGGAAGAGTGGAAGTTAATTTTGTCTTCTAAAGATGATGAAATCATTGAATA TCAGCAAATGCTACAGAGTCTGAGAGGGAAACTTAAAAATGCCCAACTTGATGCAGACAAAAGTAACATC ATGGCTCTGAAACAGGGTATCCAGGAGCGAGACAGTCAAATTAAGATGCTTACTGAGCAAGTAGAACAGT ATACGAAAGAAATGGAAAAAAATACGTTTATTATTGAAGATTTGAAAAATGAACTCCAAAAAGACAAAGG TACTTCAAACTTTTATCAGCAGACTCATTATATGAAAATTCACTCAAAAGTACAAATTTTAGAAGAGAAA ACAAAAGAGGCCGAGAGAATAGCTGAGCTGGCTGAGGCTGATGCCAGGGAGAAGGACAAAGAATTGGTTG AGGCTCTGAAGAGATTAAAAGATTATGAATCTGGAGTATATGGCTTAGAAGATGCTGTTATCGAAATAAA GAATTGTAAAGCCCAAATTAAAATAAGAGATGGAGAGATGGAAGTGTTGACCAAGGAGATCAATAAGCTT GAGATGAAGATCAATGACATCCTTGATGAAAACGAAGCCCTTAGAGAGCGGGCTGGCCTTGAACCCAAGA CAATGATTGATTTGACTGAATTTAGAAACAGCAAACGGTTAAAGCAGCAACAGTACAGAGCTGAGAACCA GGTTCTTTTGAAAGAGATCGAAAGTCTAGAGGAGGAGCGTCTTGACTTGAAAAGAAAGATTCGTCAAATG GCTCAAGAAAGAGGCAAAAGGAACGCAGCCTCAGGATTAACCATTGACGACTTGAACTTATCTGAAACCT TTTCTCATGAAAATAAAATAGAAGGAAGAAAACTAAATTTTATGAGCCTCAATAATATGAATGAAACACA ATCAAAGAATGAGTTTCTTTCAAGAGAATTGGCTGAAAAGGAAAAAGATTTAGAAAGAAGTAGGACAGTA ATTGCTAAATTCCAGAGTAAACTAAAAGAATTAGTCGAAGAAAATAAGCAACTTGAAGAAGGTATGAAAG AAATTTTGCAAGCTATTAAGGACATGCCGAAGGATTCTGATGTGAAAGGAGGTGAAACATCTTTAATCAT CCCGAGTCTTGAAAGACTGGTTAACGCTATGGAATCAAAGAATGCAGAAGGAATCTTCGATGCCAGCTTG CATCTAAAAGCCCAAGTTGACCAACTTACAGGAAGGAATGAAGAATTAAGGCAAGAACTCAGGCAATCTC GGAAAGAGGCTGTAAATTATTCACAGCAGTTGGTAAAAGCAAACTTAAAGATTGACCACCTTGAGAAGGA AACTGACCTTCTACGTCAGTCTGCAGGCTCCAATGTAGTATACAAAGGCATAGACTTACCCGATGGGATA GCACCATCCAGTGCCTATATCATCAATTCTCAGAATGAATACTTAATACATCTTTTGCAGGAACTAGACA ATAAAGAAAAGAAATTAAAACATTTAGAAGATTCCCTTGAAGATTATAACAGAAAGTTTGCAGTGATTCG TCATCAACAAAGTTTATTATATAAAGAATACCTAAGTGAAAAGGATATTTGGAAAACAGACTCTGAGATG ATAAGAGAGGAGAAGAGAAAACTGGAAGATCAAGCTGAGCAGGATGCTGTGAAAGTAAAAGAGTACAACA ATTTGCTCAGTGCTCTTCAGATGGATTCGAACGAGATGAAGAAAATGCTCTCAGAAAACAGTAGGAAAAT CACCGTTCTGCAAGTGAACGAGAAGTCCCTCATCCGGCAGTACACCACCTTAGTGGAGATGGAGCGGCAC CTGAGAAAGGAAAACGGGAAACACAGGAATGACGTCATAGCCATGGAAGCCGAAGTCACTGAAAAACTTG GAAGTTTGCAAAGATTCAAGGAAATGGCCATCTTCAAGATTGCAGCTCTTCAGAAGGTTATAGATAATAG TGTTTCTTTGTCTGAATTAGAACTAGCCAATAAACAGTACAATGAGCTGACTACTAAGTACAGGGACATC TTGCAGAAAGATAATATGCTTGTTCAAAGAACAAGTAACTTAGAACACCTGGAGTGTGAGAATGCATCGC TAAAAGAACAGATGGAGGCTATCAGTAAAGAGCTGGAGATTACAAAGGAAAAACTCCATACCATTGAACA GGCCTGGGAACAAGAAACGAAGTTAGGAAATGACTCAAACATGGATAAGGCTAAGAAATCAATGACAAAC AGTGACATTGTTTCTATTTCAAAGAAAATCACTGTGTTGGAGATGAAGGAATTAAATGAAAGGCAGAGGG CTGAACACTGTCAGAAAATGTATGAGCACTTAAGGACTTCATTAAAGCAAATGGAAGAACGTAATTTTGA ATTGGAAACCAAGTTCACTGAGCTTACTAAAATCAACCTGGATGCACAAAAGGTGGAGCAGATGTTGAGA GACGAATTAGCTGATAGTGTGACCAAGGCAGTAAGTGATGCTGACCGACAGCGGATTCTAGAACTAGAGA AGAGTGAAGTGGAGCTCAAAGTTGAAGTGTCCAAGCTGAGAGAGATTTCAGATATTGCCAAAAGACAAGT TGATTTTTTGAATTCGCAACAACAGTCCAGGGAAAAGGAAGTGGAATCCCTCAGAACGCAGCTGCTGGAC TTCCAGGCACAATCTGACGAAAAGGCTCTAATTGCCAAATTGCACCAACATGTTGTCTCTCTTCAAATTA GTGAGGCCACTGCCCTCGGTAAGTTAGAGTCAGTTACGTCCAAACTCCAGAAGATGGAAGCCTACAATTT GCGCTTAGAACAGAAACTGGATGAAAAAGAGCAGGCGCTCTACTATGCTCGTTTGGAAGGTAGAAACAGA GCAAAACACCTGCGCCAAACCATTCAGTCGCTTCGAAGACAGTTCAGTGGAGCTCTACCCTTAGCACAGC AGGAAAAGTTCTCCAAAACGATGATTCAGTTGCAAAATGACAAACTTAAGATAATGCAAGAAATGAAGAA TTCGCAACAGGAACACAGAAATATGGAAAACAAAACACTGGAGTTGGAATTAAAATTAAAAGGCTTAGAA GAATTGATCAGTACTTTAAAGGATGCCAGGGGAGCCCAGAAGGTAATCAATTGGCATGTGAAAATAGAAG AACTTCGCCTCCAAGAACTTAAGCTAAATAGAGAACTAGTCAAGGGTAAAGAAGAAATCAAATATTTGAA TAATATCATCTCTGAATATGAGCATACAATCAACAGTCTAGAGGAAGAAATTGTTCAGCAAAGCAAGTTC CATGAAGAAAGACAGATGGCTTGGGATCAAAGAGAAGTTGAGCTGGAACGCCAGTTAGACATTTTTGATC ATCAGCAAAATGAAATACTCAGTGCAGCACAAAAGTTTGAAGACTCTACAGGATCAATGCCAGACCCCAG CTTGCCTCTTCCAAACCAACTTGAAATTGCTCTAAGAAAAATTAAGGAGAATATTCAAGTAATTCTTAAA ACACAAGCAACTTGCAAGTCACTAGAAGAGAAACTAAAAGAAAAAGAATCTGCTTTACGGTTGGCAGAGC AAAATATTCTGTCAAGAGACAAAGTAATCAATGAACTGAGGCTTCGATTGCCTGCCACGGCTGATCGAGA AAAACTTATAGCTGAGCTAGAAAGAAAAGAGCTGGAGCCGAAATCTCATCACACAATGAAAATTGCCCAC CAAACTATTGCCAACATGCAGGCAAGGTTAAATCACAAGGAAGAAGTATTGAAGAAATACCAGCACCTTC TGGAGAAGGCCAGAGAGGAGCAAAGAGAAATTGTTAAGAAGCATGAGGAAGACCTTCATGTTCTTCATCA CAAATTAGAACAACAGGCCGATAATTCACTCAATAAATTCAGACAGACAGCTCAGGATTTACTTAAGCAG TCTCCTGCTCCAGTTCCCACCAACAAACATTTCATTCGTCTGGCCGAGATGGAGCAGACAGTAGCAGAAC AAGATGACTCTCTGTCCTCACTTTTGACCAAACTAAAGAAAGTATCAAAAGATTTGGAAAAACAAAAAGA AATCACTGAGTTAAAAGTCAGAGAGTTTGAAAATACCAAACTACGGCTCCAAGAAACTCATGCCAGTGAG GTAAAGAAAGTGAAAGCAGAGGTAGAGGACTTAAGGCATGCTCTAGCCCAAGCACACAAGGACTCCCAGA GTTTAAAGTCTGAACTCCAGGCTCAGAAAGAAGCAAACTCCAGAGCTCCAACAACCACAATGAGGAATCT TGTAGACAGGCTAAAGAGCCAACTAGCCTTGAAAGAGAAGCAACAAAAGGCACTTAGTCGAGCCCTGTTG GAACTTCGGTCGGAAATGACAGCAGCAGCTGAGGAACGTATAATCGCTGTAACTTCTCAAAAAGAGGCAA ATCTCAATGTTCAACAAGTTGTTGAGCGCCATACTAGAGAGCTAAAGTCACAAATTGAAGATTTAAATGA AAATCTTTTAAAATTGAAAGAAGCTCTTAAAACAAGTAAGAACAAAGAAAATTCACTAGCTGATGATTTA AATGAATTAAATAATGAACTGCAAAAAAAGCAAAAAGCTTATAATAAAATCCTTAGAGAGAAAGATGGAA TTGATCAAGAAAATGATGAACTGAGAAGACAGATTAAAAGACTGTCCAGTGGACTGCAGAGCAAAACTTT GATAGATAACAAGCAAAGTTTAATCGATGAACTTCAAAAGAAAGTTAAAAAACTTGAAAGCCAACTGGAA AGAAAGGTGGATGACGTAGACATAAAGCCGGTGAAGGAAAAGAGTAGTAAAGAAGAATTAATTAGGTGGG AAGAAGGTAAGAAATGGCAAACCAAAGTAGAGGGACTACGAAACAGACTAAAGGAGAAGGAAGGAGAAGC CCACGGCCTGGCAAAGCAGCTGAATACCTTAAAGGAACTTTTTGCCAAAGCTGATAAAGAGAAACTTACT TTGCAGAAGAAACTGAAAACAACAGGAATGACTGTTGACCAGGTTTTAGGAGTGCGAGCTTTGGAATCTG AAAAAGAGTTGGAAGAGCTAAAAAAGAAAAATCTGGACCTAGAAAATGACATATTATACATGAGGACCCA GCAGGCTCTTCCACGAGATTCTGTTGTGGAAGACTTACATTTACAAAATAAATACCTTCAAGAAAAACTT CATACTTTAGAAAAAAAACTTTCAAAGGAGAAATATTCTCAGTCTTTGACTTCAGAAATAGAGTCAGATG ATCACTGTCAAAAAGAACAAGAACTTCAGAAGGAAAATTTGAAGTTGTCATCTGAAAACATCGAGCTGAA ATTTCAACTTGAACAAGCAAATAAAGATTTGCCAAGACTAAAGAATCAAGTGAAAGATTTGAAGGAAATG TGTGAATTTCTTAAGAAAGGAAAACTGGAACTTGAGCGGAAGCTTGGTCAGGTCAGAGGGGCTGGTAGAA GTGGGAAGACAATCCCAGAACTAGAAAAAACCATTGGGTTAATGAAGAAAGTAGTTGAAAAAGTCCAAAG AGAAAATGAACAATTGAAAAAGGCATCAGGAATACTGACTAGTGAAAAAATGGCTACTATTGAGGAAGAA AATAGAAACTTAAAGGCTGAACTAGAAAAGCTTAAAGCTCACTTTGGACGTCAGTTGAGTATGCAGTTTG AATCTAAGAACAAAGGTACTGAGAAAATTGTTGCCGAAAATGAACGGCTTCGGAAAGAACTTAAGAAAGA AATAGAAGCCTCTGAGAAACTGCGGATAGCTAAGAACAACTTAGAGCTGGTGAACGACAAGATGGCAGCT CAACTCGAAGAAACTGGGAAGAGACTACAGTTTGCAGAAAGTAGAGCCCCACAGCTGGAAGGTGCTGACA GCAAGAGCTGGAAGTCAATTGTGGTCTCAAGAGTGTATGAGACCAAGATGAAAGAGCTTGAAAGTGACAT TGCCAAAAAGAATCAAAGTATCACTGACCTTAAACAGCTTGTAAGAGAAGCAACAGAGAGAGAACAGAAA GCTAAGAAATACACTGAAGACCTTGAACAACAGATTGAGATCCTCAAAAATGTTCCTGAAGGTGCCGAGA CAGAGCAAGAGCTTATACGGGAACTCCAGCTTCTTAGATTAGCCAATAATCAGATGGATAAAGAAAGGGC AGAATTAATCCATCAGATAGAAATTAACAAGGACCAAACCAGAGCTGACAGTAGCATACCTGATTCTGAT CAACTAAAGGAAAAGATAAATGACCTGGAGACACAACTCAGAAAGTTGGAGCTAGAAAAGCAACATTCGA AGGAGGAAGTTAAAAAGCTGAAAAAAGAACTGGAAAATTTTGATCCTTCATTTTTTGAAGAAATTGAAGA CCTGAAGTATAATTATAAGGAAGAAGTGAAAAAGAATATCCTATTAGAAGAGAAGCTAAAAAAACTGTCG GAACAGTTTGGATTTGAACTGCCTAGTCCTCTTGCTGCTTCTGAACACTCGGAAGATGGAGAAAGTCCTC ATAGTTTCCCTATTTAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >MR222042 representing NM_146009 Red=Cloning site Green=Tags(s) MPPNIKWKELIKVDPDDLPRQEELADKLLISLSKVEVNELKNEDQENMIHLFRITQSLMKMKAQEVELAL EEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRDEIRQLEKQLEQKDRELEDMEKELDK EKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLRQDIIDYQKQIDSQKESLLSRRGEDSDYRSQLSK KNYELVQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKALVHQSDAVMDQIKKENEH YRLQVRELTDLLKAKDEEDDPVMMAVNAKVEEWKLILSSKDDEIIEYQQMLQSLRGKLKNAQLDADKSNI MALKQGIQERDSQIKMLTEQVEQYTKEMEKNTFIIEDLKNELQKDKGTSNFYQQTHYMKIHSKVQILEEK TKEAERIAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVIEIKNCKAQIKIRDGEMEVLTKEINKL EMKINDILDENEALRERAGLEPKTMIDLTEFRNSKRLKQQQYRAENQVLLKEIESLEEERLDLKRKIRQM AQERGKRNAASGLTIDDLNLSETFSHENKIEGRKLNFMSLNNMNETQSKNEFLSRELAEKEKDLERSRTV IAKFQSKLKELVEENKQLEEGMKEILQAIKDMPKDSDVKGGETSLIIPSLERLVNAMESKNAEGIFDASL HLKAQVDQLTGRNEELRQELRQSRKEAVNYSQQLVKANLKIDHLEKETDLLRQSAGSNVVYKGIDLPDGI APSSAYIINSQNEYLIHLLQELDNKEKKLKHLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKDIWKTDSEM IREEKRKLEDQAEQDAVKVKEYNNLLSALQMDSNEMKKMLSENSRKITVLQVNEKSLIRQYTTLVEMERH LRKENGKHRNDVIAMEAEVTEKLGSLQRFKEMAIFKIAALQKVIDNSVSLSELELANKQYNELTTKYRDI LQKDNMLVQRTSNLEHLECENASLKEQMEAISKELEITKEKLHTIEQAWEQETKLGNDSNMDKAKKSMTN SDIVSISKKITVLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFTELTKINLDAQKVEQMLR DELADSVTKAVSDADRQRILELEKSEVELKVEVSKLREISDIAKRQVDFLNSQQQSREKEVESLRTQLLD FQAQSDEKALIAKLHQHVVSLQISEATALGKLESVTSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNR AKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLELELKLKGLE ELISTLKDARGAQKVINWHVKIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKF HEERQMAWDQREVELERQLDIFDHQQNEILSAAQKFEDSTGSMPDPSLPLPNQLEIALRKIKENIQVILK TQATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATADREKLIAELERKELEPKSHHTMKIAH QTIANMQARLNHKEEVLKKYQHLLEKAREEQREIVKKHEEDLHVLHHKLEQQADNSLNKFRQTAQDLLKQ SPAPVPTNKHFIRLAEMEQTVAEQDDSLSSLLTKLKKVSKDLEKQKEITELKVREFENTKLRLQETHASE VKKVKAEVEDLRHALAQAHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEKQQKALSRALL ELRSEMTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDLNENLLKLKEALKTSKNKENSLADDL NELNNELQKKQKAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSLIDELQKKVKKLESQLE RKVDDVDIKPVKEKSSKEELIRWEEGKKWQTKVEGLRNRLKEKEGEAHGLAKQLNTLKELFAKADKEKLT LQKKLKTTGMTVDQVLGVRALESEKELEELKKKNLDLENDILYMRTQQALPRDSVVEDLHLQNKYLQEKL HTLEKKLSKEKYSQSLTSEIESDDHCQKEQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVKDLKEM CEFLKKGKLELERKLGQVRGAGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMATIEEE NRNLKAELEKLKAHFGRQLSMQFESKNKGTEKIVAENERLRKELKKEIEASEKLRIAKNNLELVNDKMAA QLEETGKRLQFAESRAPQLEGADSKSWKSIVVSRVYETKMKELESDIAKKNQSITDLKQLVREATEREQK AKKYTEDLEQQIEILKNVPEGAETEQELIRELQLLRLANNQMDKERAELIHQIEINKDQTRADSSIPDSD QLKEKINDLETQLRKLELEKQHSKEEVKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKLKKLS EQFGFELPSPLAASEHSEDGESPHSFPIY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms	CHROMATOGRAMS Sequencher program is needed, download here.
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_146009
ORF Size	7437 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_146009.3
RefSeq Size	8006 bp
RefSeq ORF	7440 bp
Locus ID	216274
UniProt ID	Q6A078
MW	290 kDa
Gene Summary	Involved in early and late steps in cilia formation (PubMed:21565611). Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (By similarity). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1 (By similarity). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (PubMed:16632484). Required for efficient recruitment of RAB8A to primary cilium (By similarity). In the ciliary transition zone is part of the tectonic-like complex (also named B9 complex) which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (PubMed:21725307). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2, BBS5 and BBS8/TTC8 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating IQCB1/NPHP5 (By similarity). Activates ATF4-mediated transcription (By similarity).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.