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Il4ra (NM_001008700) Mouse Tagged ORF Clone
CAT＃: MR227371
- TrueORF®
Il4ra (Myc-DDK-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra)
ORF Plasmid: tGFP
"NM_001008700" in other vectors (6)
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CNY 8,912.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CD124; Il4r |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR227371 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGCGGCTTTGCACCAAGTTCCTGACCTCTGTGGGCTGTCTGATTTTGCTGTTGGTGACTGGATCTG GGAGCATCAAGGTCCTGGGTGAGCCCACCTGCTTCTCTGACTACATCCGCACTTCCACGTGTGAGTGGTT CCTGGATAGCGCTGTGGACTGCAGTTCTCAGCTCTGCCTACACTACAGGCTGATGTTCTTCGAGTTCTCT GAAAACCTCACATGCATCCCGAGGAACAGTGCCAGCACTGTGTGTGTGTGCCACATGGAAATGAATAGGC CGGTCCAATCAGACAGATACCAGATGGAACTGTGGGCTGAGCACAGACAGCTGTGGCAGGGCTCCTTCAG CCCCAGTGGTAATGTGAAGCCCCTAGCTCCAGACAACCTCACACTCCACACCAATGTGTCCGACGAATGG CTGCTGACCTGGAATAACCTGTACCCATCGAACAACTTACTGTACAAAGACCTCATCTCCATGGTCAACA TCTCCAGAGAGGACAACCCTGCAGAATTCATAGTCTATAATGTGACCTACAAGGAACCCAGGCTGAGCTT CCCGATCAACATCCTGATGTCAGGGGTCTACTATACGGCGCGTGTGAGGGTCAGATCCCAGATACTCACT GGCACCTGGAGTGAGTGGAGTCCTAGCATCACGTGGTACAACCACTTCCAGCTGCCCCTGATACAGCGCC TTCCACTGGGGGTCACCATCTCCTGCCTCTGCATCCCGTTGTTTTGCCTGTTCTGTTACTTCAGCATTAC CAAGATTAAGAAGATATGGTGGGACCAGATTCCCACCCCAGCACGCAGTCCCTTGGTGGCCATCATCATT CAGGATGCACAGGTGCCCCTCTGGGATAAGCAGACCCGAAGCCAGGAGTCAACCAAGTACCCGCACTGGA AAACTTGTCTAGACAAGCTGCTGCCTTGCTTGCTGAAGCACAGAGTAAAGAAGAAGACAGACTTCCCGAA GGCTGCCCCAACCAAGTCTCTCCAGAGTCCTGGAAAGGCAGGCTGGTGTCCCATGGAGGTCAGCAGGACC GTCCTCTGGCCAGAGAATGTTAGTGTCAGTGTGGTGCGCTGTATGGAGCTGTTTGAGGCCCCAGTACAGA ATGTGGAGGAGGAAGAAGATGAGATAGTCAAAGAGGACCTGAGCATGTCACCTGAGAACAGCGGAGGCTG CGGCTTCCAGGAGAGCCAGGCAGACATCATGGCTCGGCTCACTGAGAACCTGTTTTCCGACTTGTTGGAG GCTGAGAATGGGGGCCTTGGCCAGTCAGCCTTGGCAGAGTCATGCTCCCCTCTGCCTTCAGGAAGTGGGC AGGCTTCTGTATCCTGGGCCTGCCTCCCCATGGGGCCCAGTGAGGAGGCCACATGCCAGGTCACAGAGCA GCCTTCACACCCAGGCCCTCTTTCAGGCAGCCCAGCCCAGAGTGCACCTACTCTGGCTTGCACGCAGGTC CCACTTGTCCTTGCAGACAATCCTGCCTACCGGAGTTTTAGTGACTGCTGTAGCCCGGCCCCAAATCCTG GAGAGCTGGCTCCAGAGCAGCAGCAGGCTGATCATCTGGAAGAAGAGGAGCCTCCAAGCCCGGCTGACCC CCATTCTTCAGGGCCACCAATGCAGCCAGTGGAGAGCTGGGAGCAGATCCTTCACATGAGTGTCCTGCAG CATGGGGCAGCTGCTGGCTCCACCCCAGCCCCTGCCGGTGGCTACCAGGAGTTTGTGCAGGCAGTGAAGC AGGGTGCCGCCCAGGATCCTGGGGTGCCTGGTGTCAGGCCTTCTGGAGACCCCGGTTACAAGGCCTTCTC GAGCCTGCTCAGCAGCAATGGCATCCGCGGGGACACAGCAGCAGCGGGGACTGACGATGGGCATGGAGGC TACAAGCCCTTCCAGAATCCTGTTCCTAACCAGTCCCCTAGCTCCGTGCCCTTATTTACTTTCGGACTAG ACACGGAGCTGTCACCCAGTCCTCTGAACTCAGACCCACCCAAAAGCCCCCCAGAATGCCTTGGTCTGGA GCTGGGGCTCAAAGGAGGTGACTGGGTGAAGGCCCCTCCTCCTGCAGATCAGGTGCCCAAGCCCTTTGGG GATGACCTGGGCTTTGGTATTGTGTACTCGTCCCTCACTTGCCACTTGTGTGGCCACCTGAAGCAACACC ACAGCCAGGAGGAAGGTGGCCAGAGCCCCATCGTTGCTAGCCCTGGCTGTGGCTGCTGCTACGATGACAG ATCACCATCCCTGGGGAGCCTCTCGGGGGCCTTGGAAAGCTGTCCTGAGGGAATACCACCAGAAGCCAAC CTCATGTCAGCACCCAAGACACCCTCAAACTTGTCAGGGGAGGGCAAGGGCCCTGGTCACTCTCCTGTTC CCAGCCAGACGACCGAGGTGCCTGTGGGCGCCCTGGGCATTGCTGTTTCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR227371 protein sequence
Red=Cloning site Green=Tags(s) MGRLCTKFLTSVGCLILLLVTGSGSIKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFS ENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEW LLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILT GTWSEWSPSITWYNHFQLPLIQRLPLGVTISCLCIPLFCLFCYFSITKIKKIWWDQIPTPARSPLVAIII QDAQVPLWDKQTRSQESTKYPHWKTCLDKLLPCLLKHRVKKKTDFPKAAPTKSLQSPGKAGWCPMEVSRT VLWPENVSVSVVRCMELFEAPVQNVEEEEDEIVKEDLSMSPENSGGCGFQESQADIMARLTENLFSDLLE AENGGLGQSALAESCSPLPSGSGQASVSWACLPMGPSEEATCQVTEQPSHPGPLSGSPAQSAPTLACTQV PLVLADNPAYRSFSDCCSPAPNPGELAPEQQQADHLEEEEPPSPADPHSSGPPMQPVESWEQILHMSVLQ HGAAAGSTPAPAGGYQEFVQAVKQGAAQDPGVPGVRPSGDPGYKAFSSLLSSNGIRGDTAAAGTDDGHGG YKPFQNPVPNQSPSSVPLFTFGLDTELSPSPLNSDPPKSPPECLGLELGLKGGDWVKAPPPADQVPKPFG DDLGFGIVYSSLTCHLCGHLKQHHSQEEGGQSPIVASPGCGCCYDDRSPSLGSLSGALESCPEGIPPEAN LMSAPKTPSNLSGEGKGPGHSPVPSQTTEVPVGALGIAVS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001008700 |
| ORF Size | 2433 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001008700.4 |
| RefSeq Size | 5122 bp |
| RefSeq ORF | 2433 bp |
| Locus ID | 16190 |
| UniProt ID | P16382 |
| MW | 87.6 kDa |
| Gene Summary | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC221751 | Il4ra (untagged) - Mouse interleukin 4 receptor, alpha (Il4ra), (10ug) |
CNY 10,360.00 |
|
| MG227371 | Il4ra (tGFP-tagged) - Mouse interleukin 4 receptor alpha (Il4ra), (10ug) |
CNY 10,512.00 |
|
| MR227371L1 | Lenti ORF clone of Il4ra (Myc-DDK-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra) |
CNY 9,980.00 |
|
| MR227371L2 | Lenti ORF clone of Il4ra (mGFP-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra) |
CNY 9,980.00 |
|
| MR227371L3 | Lenti ORF clone of Il4ra (Myc-DDK-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra) |
CNY 9,980.00 |
|
| MR227371L4 | Lenti ORF clone of Il4ra (mGFP-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra) |
CNY 9,980.00 |
