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PROX1 (NM_002763) Human Tagged ORF Clone
CAT＃: RC201140
PROX1 (Myc-DDK-tagged)-Human prospero homeobox 1 (PROX1)
ORF Plasmid: tGFP
"NM_002763" in other vectors (6)
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CNY 8,104.00
| Cited in 3 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC201140 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTGACCATGACAGCACAGCCCTCTTAAGCCGGCAAACCAAGAGGAGAAGAGTTGACATTGGAGTGA AAAGGACGGTAGGGACAGCATCTGCATTTTTTGCTAAGGCAAGAGCAACGTTTTTTAGTGCCATGAATCC CCAAGGTTCTGAGCAGGATGTTGAGTATTCAGTGGTGCAGCATGCAGATGGGGAAAAGTCAAATGTACTC CGCAAGCTGCTGAAGAGGGCGAACTCGTATGAAGATGCCATGATGCCTTTTCCAGGAGCAACCATAATTT CCCAGCTGTTGAAAAATAACATGAACAAAAATGGTGGCACGGAGCCCAGTTTCCAAGCCAGCGGTCTCTC TAGTACAGGCTCCGAAGTACATCAGGAGGATATATGCAGCAACTCTTCAAGAGACAGCCCCCCAGAGTGT CTTTCCCCTTTTGGCAGGCCTACTATGAGCCAGTTTGATATGGATCGCTTATGTGATGAGCACCTGAGAG CAAAGCGCGCCCGGGTTGAGAATATAATTCGGGGTATGAGCCATTCCCCCAGTGTGGCATTAAGGGGCAA TGAAAATGAAAGAGAGATGGCCCCGCAGTCTGTGAGTCCCCGAGAAAGTTACAGAGAAAACAAACGCAAG CAAAAGCTTCCCCAGCAGCAGCAACAGAGTTTCCAGCAGCTGGTTTCAGCCCGAAAAGAACAGAAGCGAG AGGAGCGCCGACAGCTGAAACAGCAGCTGGAGGACATGCAGAAACAGCTGCGCCAGCTGCAGGAAAAGTT CTACCAAATCTATGACAGCACTGATTCGGAAAATGATGAAGATGGTAACCTGTCTGAAGACAGCATGCGC TCGGAGATCCTGGATGCCAGGGCCCAGGACTCTGTCGGAAGGTCAGATAATGAGATGTGCGAGCTAGACC CAGGACAGTTTATTGACCGAGCTCGAGCCCTGATCAGAGAGCAGGAAATGGCTGAAAACAAGCCGAAGCG AGAAGGCAACAACAAAGAAAGAGACCATGGGCCAAACTCCTTACAACCGGAAGGCAAACATTTGGCTGAG ACCTTGAAACAGGAACTGAACACTGCCATGTCGCAAGTTGTGGACACTGTGGTCAAAGTCTTTTCGGCCA AGCCCTCCCGCCAGGTTCCTCAGGTCTTCCCACCTCTCCAGATCCCCCAGGCCAGATTTGCAGTCAATGG GGAAAACCACAATTTCCACACCGCCAACCAGCGCCTGCAGTGCTTTGGCGACGTCATCATTCCGAACCCC CTGGACACCTTTGGCAATGTGCAGATGGCCAGTTCCACTGACCAGACAGAAGCACTGCCCCTGGTTGTCC GCAAAAACTCCTCTGACCAGTCTGCCTCCGGCCCTGCCGCTGGCGGCCACCACCAGCCCCTGCACCAGTC GCCTCTCTCTGCCACCACGGGCTTCACCACGTCCACCTTCCGCCACCCCTTCCCCCTTCCCTTGATGGCC TATCCATTTCAGAGCCCATTAGGTGCTCCCTCCGGCTCCTTCTCTGGAAAAGACAGAGCCTCTCCTGAAT CCTTAGACTTAACTAGGGATACCACGAGTCTGAGGACCAAGATGTCATCTCACCACCTGAGCCACCACCC TTGTTCACCAGCACACCCGCCCAGCACCGCCGAAGGGCTCTCCTTGTCGCTCATAAAGTCCGAGTGCGGC GATCTTCAAGATATGTCTGAAATATCACCTTATTCGGGAAGTGCAATGCAGGAAGGATTGTCACCCAATC ACTTGAAAAAAGCAAAGCTCATGTTTTTTTATACCCGTTATCCCAGCTCCAATATGCTGAAGACCTACTT CTCCGACGTAAAGTTCAACAGATGCATTACCTCTCAGCTCATCAAGTGGTTTAGCAATTTCCGTGAGTTT TACTACATTCAGATGGAGAAGTACGCACGTCAAGCCATCAACGATGGGGTCACCAGTACTGAAGAGCTGT CTATAACCAGAGACTGTGAGCTGTACAGGGCTCTGAACATGCACTACAATAAAGCAAATGACTTTGAGGT TCCAGAGAGATTCCTGGAAGTTGCTCAGATCACATTACGGGAGTTTTTCAATGCCATTATCGCAGGCAAA GATGTTGATCCTTCCTGGAAGAAGGCCATATACAAGGTCATCTGCAAGCTGGATAGTGAAGTCCCTGAGA TTTTCAAATCCCCGAACTGCCTACAAGAGCTGCTTCATGAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC201140 protein sequence
Red=Cloning site Green=Tags(s) MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVL RKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPEC LSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRK QKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMR SEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAE TLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNP LDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTFRHPFPLPLMA YPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECG DLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREF YYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGK DVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_002763 |
| ORF Size | 2214 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002763.5 |
| RefSeq Size | 8178 bp |
| RefSeq ORF | 2214 bp |
| Locus ID | 5629 |
| UniProt ID | Q92786 |
| Domains | Prox1 |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS |
| MW | 83.2 kDa |
| Gene Summary | The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma
,Kim, YJ;Yoo, JE;Jeon, Y;Uk Chong, J;Choi, GH;Song, DG;Jung, SH;Oh, BK;Park, YN;,
Int. J. Cancer
,PubMed ID 29987895
[PROX1]
|
|
PROX1 promotes human glioblastoma cell proliferation and invasion via activation of the nuclear factor-κB signaling pathway
,Xu, X;Wan, X;Wei, X;,
Mol Med Rep
,PubMed ID 28035380
[PROX1]
|
|
PROX1 Gene is Differentially Expressed in Oral Cancer and Reduces Cellular Proliferation
,Rodrigues, MF;de Oliveira Rodini, C;de Aquino Xavier, FC;Paiva, KB;Severino, P;Moyses, RA;López, RM;DeCicco, R;Rocha, LA;Carvalho, MB;Tajara, EH;Nunes, FD;,
Medicine (Baltimore)
,PubMed ID 25526434
[PROX1]
|
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201140L1 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), Myc-DDK-tagged |
CNY 10,504.00 |
|
| RC201140L2 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), mGFP tagged |
CNY 5,890.00 |
|
| RC201140L3 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), Myc-DDK-tagged |
CNY 10,504.00 |
|
| RC201140L4 | Lenti ORF clone of Human prospero homeobox 1 (PROX1), mGFP tagged |
CNY 10,504.00 |
|
| RG201140 | PROX1 (tGFP-tagged) - Human prospero homeobox 1 (PROX1) |
CNY 9,704.00 |
|
| SC318217 | PROX1 (untagged)-Human prospero homeobox 1 (PROX1) |
CNY 8,104.00 |
