CBX6 (NM_014292) Human Tagged ORF Clone
CAT#: RC204166
CBX6 (Myc-DDK-tagged)-Human chromobox homolog 6 (CBX6)
ORF Plasmid: tGFP
"NM_014292" in other vectors (6)
Need custom modification / cloning service?
Get a free quote
CNY 3,656.00
CNY 3,990.00
Cited in 2 publications. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC204166 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCTGTCTGCAGTGGGCGAGCGGGTCTTCGCGGCCGAATCCATCATCAAACGGCGGATCCGAAAGG GACGCATCGAGTACCTGGTGAAATGGAAGGGGTGGGCGATCAAGTACAGCACTTGGGAGCCCGAGGAGAA CATCCTGGACTCGCGGCTCATTGCAGCCTTCGAACAAAAGGAGAGGGAGCGTGAGCTGTATGGGCCCAAG AAGAGGGGACCCAAACCCAAAACTTTCCTCCTGAAGGCGCGGGCCCAGGCCGAGGCCCTCCGCATCAGTG ATGTGCATTTCTCTGTCAAGCCGAGCGCCAGTGCCTCCTCGCCCAAGCTGCACTCCAGCGCAGCCGTGCA CCGGCTCAAGAAGGACATCCGCCGCTGCCACCGTATGTCCCGCCGTCCCCTGCCCCGCCCGGACCCGCAG GGGGGCAGCCCCGGACTGCGCCCGCCCATTTCGCCCTTCTCGGAGACGGTGCGCATCATCAACCGCAAGG TGAAGCCGCGGGAGCCCAAGCGGAACCGCATCATCCTGAACCTGAAGGTGATCGACAAGGGCGCTGGCGG CGGGGGCGCCGGGCAGGGGGCCGGGGCGCTGGCCCGCCCCAAAGTCCCCTCGCGGAACCGCGTTATAGGC AAGAGCAAGAAGTTCAGCGAGAGCGTCCTGCGTACACAGATCCGCCACATGAAGTTCGGCGCCTTTGCGC TGTACAAGCCTCCGCCCGCCCCCCTGGTAGCCCCGTCCCCCGGCAAGGCTGAGGCCTCAGCCCCGGGCCC TGGGCTACTTCTGGCCGCCCCCGCCGCCCCCTACGACGCCCGCAGCTCTGGCTCCTCCGGCTGCCCCTCG CCTACACCACAGTCCTCTGACCCCGACGACACGCTCCCCAAGCTCCTCCCCGAGACCGTGAGCCCATCCG CCCCCAGCTGGCGCGAGCCGGAGGTGCTCGACCTGTCCCTCCCTCCCGAGTCGGCAGCCACCAGCAAGCG GGCACCGCCTGAGGTCACAGCTGCTGCCGGCCCGGCACCTCCCACGGCCCCTGAGCCCGCCGGTGCCTCC TCCGAGCCCGAGGCTGGGGACTGGCGCCCCGAGATGTCACCCTGCTCCAATGTGGTCGTCACCGATGTCA CCAGCAACCTCCTGACGGTCACAATCAAGGAATTCTGCAACCCTGAGGATTTCGAGAAGGTGGCTGCTGG GGTAGCAGGCGCCGCTGGGGGCGGTGGCAGCATTGGGGCGAGCAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC204166 protein sequence
Red=Cloning site Green=Tags(s) MELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKERERELYGPK KRGPKPKTFLLKARAQAEALRISDVHFSVKPSASASSPKLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQ GGSPGLRPPISPFSETVRIINRKVKPREPKRNRIILNLKVIDKGAGGGGAGQGAGALARPKVPSRNRVIG KSKKFSESVLRTQIRHMKFGAFALYKPPPAPLVAPSPGKAEASAPGPGLLLAAPAAPYDARSSGSSGCPS PTPQSSDPDDTLPKLLPETVSPSAPSWREPEVLDLSLPPESAATSKRAPPEVTAAAGPAPPTAPEPAGAS SEPEAGDWRPEMSPCSNVVVTDVTSNLLTVTIKEFCNPEDFEKVAAGVAGAAGGGGSIGASK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_014292 |
ORF Size | 1236 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_014292.2 |
RefSeq Size | 3284 bp |
RefSeq ORF | 1239 bp |
Locus ID | 23466 |
UniProt ID | O95503 |
Protein Families | Transcription Factors |
MW | 43.9 kDa |
Gene Summary | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer
,Deng, H;Guan, X;Gong, L;Zeng, J;Zhang, H;Chen, MY;Li, G;,
Sci Rep
,PubMed ID 30655550
[CBX6]
|
Altered expression of polycomb group genes in glioblastoma multiforme
,Li, G;Warden, C;Zou, Z;Neman, J;Krueger, JS;Jain, A;Jandial, R;Chen, M;,
PLoS ONE e80970
,PubMed ID 24260522
[CBX6]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204166L1 | Lenti ORF clone of Human chromobox homolog 6 (CBX6), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC204166L2 | Lenti ORF clone of Human chromobox homolog 6 (CBX6), mGFP tagged |
CNY 5,890.00 |
|
RC204166L3 | Lenti ORF clone of Human chromobox homolog 6 (CBX6), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204166L4 | Lenti ORF clone of Human chromobox homolog 6 (CBX6), mGFP tagged |
CNY 5,890.00 |
|
RG204166 | CBX6 (tGFP-tagged) - Human chromobox homolog 6 (CBX6) |
CNY 4,370.00 |
|
SC123837 | CBX6 (untagged)-Human chromobox homolog 6 (CBX6) |
CNY 7,220.00 |