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TYRO3 (NM_006293) Human Tagged ORF Clone
CAT＃: RC208260
TYRO3 (Myc-DDK-tagged)-Human TYRO3 protein tyrosine kinase (TYRO3)
ORF Plasmid: tGFP
"NM_006293" in other vectors (7)
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CNY 9,776.00
| Cited in 3 publications. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | BYK; Dtk; Etk-2; Rek; RSE; Sky; Tif |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC208260 representing NM_006293
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCTGAGGCGGAGCATGGGGCGGCCGGGGCTCCCGCCGCTGCCGCTGCCGCCGCCACCGCGGCTCG GGCTGCTGCTGGCGGCTCTGGCTTCTCTGCTGCTCCCGGAGTCCGCCGCCGCAGGTCTGAAGCTCATGGG AGCCCCGGTGAAGCTGACAGTGTCTCAGGGGCAGCCGGTGAAGCTCAACTGCAGTGTGGAGGGGATGGAG GAGCCTGACATCCAGTGGGTGAAGGATGGGGCTGTGGTCCAGAACTTGGACCAGTTGTACATCCCAGTCA GCGAGCAGCACTGGATCGGCTTCCTCAGCCTGAAGTCAGTGGAGCGCTCTGACGCCGGCCGGTACTGGTG CCAGGTGGAGGATGGGGGTGAAACCGAGATCTCCCAGCCAGTGTGGCTCACGGTAGAAGGTGTGCCATTT TTCACAGTGGAGCCAAAAGATCTGGCAGTGCCACCCAATGCCCCTTTCCAACTGTCTTGTGAGGCTGTGG GTCCCCCTGAACCTGTTACCATTGTCTGGTGGAGAGGAACTACGAAGATCGGGGGACCCGCTCCCTCTCC ATCTGTTTTAAATGTAACAGGGGTGACCCAGAGCACCATGTTTTCCTGTGAAGCTCACAACCTAAAAGGC CTGGCCTCTTCTCGCACAGCCACTGTTCACCTTCAAGCACTGCCTGCAGCCCCCTTCAACATCACCGTGA CAAAGCTTTCCAGCAGCAACGCTAGTGTGGCCTGGATGCCAGGTGCCGATGGCCGAGCTCTGCTACAGTC CTGTACAGTTCAGGTGACACAGGCCCCAGGAGGCTGGGAAGTCCTGGCTGTTGTGGTCCCTGTGCCCCCC TTTACCTGCCTGCTCCGGGACCTGGTGCCTGCCACCAACTACAGCCTCAGGGTGCGCTGTGCCAATGCCT TGGGGCCCTCTCCCTATGCTGACTGGGTGCCCTTTCAGACCAAGGGTCTAGCCCCAGCCAGCGCTCCCCA AAACCTCCATGCCATCCGCACAGATTCAGGCCTCATCTTGGAGTGGGAAGAAGTGATCCCCGAGGCCCCT TTGGAAGGCCCCCTGGGACCCTACAAACTGTCCTGGGTTCAAGACAATGGAACCCAGGATGAGCTGACAG TGGAGGGGACCAGGGCCAATTTGACAGGCTGGGATCCCCAAAAGGACCTGATCGTACGTGTGTGCGTCTC CAATGCAGTTGGCTGTGGACCCTGGAGTCAGCCACTGGTGGTCTCTTCTCATGACCGTGCAGGCCAGCAG GGCCCTCCTCACAGCCGCACATCCTGGGTACCTGTGGTCCTTGGTGTGCTAACGGCCCTGGTGACGGCTG CTGCCCTGGCCCTCATCCTGCTTCGAAAGAGACGGAAAGAGACGCGGTTTGGGCAAGCCTTTGACAGTGT CATGGCCCGGGGAGAGCCAGCCGTTCACTTCCGGGCAGCCCGGTCCTTCAATCGAGAAAGGCCCGAGCGC ATCGAGGCCACATTGGACAGCTTGGGCATCAGCGATGAACTAAAGGAAAAACTGGAGGATGTGCTCATCC CAGAGCAGCAGTTCACCCTGGGCCGGATGTTGGGCAAAGGAGAGTTTGGTTCAGTGCGGGAGGCCCAGCT GAAGCAAGAGGATGGCTCCTTTGTGAAAGTGGCTGTGAAGATGCTGAAAGCTGACATCATTGCCTCAAGC GACATTGAAGAGTTCCTCAGGGAAGCAGCTTGCATGAAGGAGTTTGACCATCCACACGTGGCCAAACTTG TTGGGGTAAGCCTCCGGAGCAGGGCTAAAGGCCGTCTCCCCATCCCCATGGTCATCTTGCCCTTCATGAA GCATGGGGACCTGCATGCCTTCCTGCTCGCCTCCCGGATTGGGGAGAACCCCTTTAACCTACCCCTCCAG ACCCTGATCCGGTTCATGGTGGACATTGCCTGCGGCATGGAGTACCTGAGCTCTCGGAACTTCATCCACC GAGACCTGGCTGCTCGGAATTGCATGCTGGCAGAGGACATGACAGTGTGTGTGGCTGACTTCGGACTCTC CCGGAAGATCTACAGTGGGGACTACTATCGTCAAGGCTGTGCCTCCAAACTGCCTGTCAAGTGGCTGGCC CTGGAGAGCCTGGCCGACAACCTGTATACTGTGCAGAGTGACGTGTGGGCGTTCGGGGTGACCATGTGGG AGATCATGACACGTGGGCAGACGCCATATGCTGGCATCGAAAACGCTGAGATTTACAACTACCTCATTGG CGGGAACCGCCTGAAACAGCCTCCGGAGTGTATGGAGGACGTGTATGATCTCATGTACCAGTGCTGGAGT GCTGACCCCAAGCAGCGCCCGAGCTTTACTTGTCTGCGAATGGAACTGGAGAACATCTTGGGCCAGCTGT CTGTGCTATCTGCCAGCCAGGACCCCTTATACATCAACATCGAGAGAGCTGAGGAGCCCACTGCGGGAGG CAGCCTGGAGCTACCTGGCAGGGATCAGCCCTACAGTGGGGCTGGGGATGGCAGTGGCATGGGGGCAGTG GGTGGCACTCCCAGTGACTGTCGGTACATACTCACCCCCGGAGGGCTGGCTGAGCAGCCAGGGCAGGCAG AGCACCAGCCAGAGAGTCCCCTCAATGAGACACAGAGGCTTTTGCTGCTGCAGCAAGGGCTACTGCCACA CAGTAGCTGT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC208260 representing NM_006293
Red=Cloning site Green=Tags(s) MALRRSMGRPGLPPLPLPPPPRLGLLLAALASLLLPESAAAGLKLMGAPVKLTVSQGQPVKLNCSVEGME EPDIQWVKDGAVVQNLDQLYIPVSEQHWIGFLSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPF FTVEPKDLAVPPNAPFQLSCEAVGPPEPVTIVWWRGTTKIGGPAPSPSVLNVTGVTQSTMFSCEAHNLKG LASSRTATVHLQALPAAPFNITVTKLSSSNASVAWMPGADGRALLQSCTVQVTQAPGGWEVLAVVVPVPP FTCLLRDLVPATNYSLRVRCANALGPSPYADWVPFQTKGLAPASAPQNLHAIRTDSGLILEWEEVIPEAP LEGPLGPYKLSWVQDNGTQDELTVEGTRANLTGWDPQKDLIVRVCVSNAVGCGPWSQPLVVSSHDRAGQQ GPPHSRTSWVPVVLGVLTALVTAAALALILLRKRRKETRFGQAFDSVMARGEPAVHFRAARSFNRERPER IEATLDSLGISDELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASS DIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQ TLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLA LESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWS ADPKQRPSFTCLRMELENILGQLSVLSASQDPLYINIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAV GGTPSDCRYILTPGGLAEQPGQAEHQPESPLNETQRLLLLQQGLLPHSSC TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_006293 |
| ORF Size | 2670 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006293.4 |
| RefSeq Size | 3949 bp |
| RefSeq ORF | 2673 bp |
| Locus ID | 7301 |
| UniProt ID | Q06418 |
| Protein Families | Druggable Genome, Protein Kinase |
| MW | 96.7 kDa |
| Gene Summary | The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Tyro3 Targeting as a Radiosensitizing Strategy in Bladder Cancer through Cell Cycle Dysregulation
,null,
International Journal of Molecular Sciences
,PubMed ID 35955805
[TYRO3]
|
|
TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells
,Chen, D;Liu, Q;Cao, G;Zhang, W;,
Aging (Albany NY) 2020
,PubMed ID 32018224
[TYRO3]
|
|
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
,Paolino, M;Choidas, A;Wallner, S;Pranjic, B;Uribesalgo, I;Loeser, S;Jamieson, AM;Langdon, WY;Ikeda, F;Fededa, JP;Cronin, SJ;Nitsch, R;Schultz-Fademrecht, C;Eickhoff, J;Menninger, S;Unger, A;Torka, R;Gruber, T;Hinterleitner, R;Baier, G;Wolf, D;Ullrich, A;Klebl, BM;Penninger, JM;,
Nature, Feb 2014.
,PubMed ID 24553136
[TYRO3]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208260L1 | Lenti ORF clone of Human TYRO3 protein tyrosine kinase (TYRO3), Myc-DDK-tagged |
CNY 12,176.00 |
|
| RC208260L2 | Lenti ORF clone of Human TYRO3 protein tyrosine kinase (TYRO3), mGFP tagged |
CNY 12,176.00 |
|
| RC208260L3 | Lenti ORF clone of Human TYRO3 protein tyrosine kinase (TYRO3), Myc-DDK-tagged |
CNY 12,176.00 |
|
| RC208260L4 | Lenti ORF clone of Human TYRO3 protein tyrosine kinase (TYRO3), mGFP tagged |
CNY 12,176.00 |
|
| RC600075 | TYRO3 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens TYRO3 protein tyrosine kinase, Signal peptide (1-40) plus EC domain (41-429) |
CNY 5,488.00 |
|
| RG208260 | TYRO3 (tGFP-tagged) - Human TYRO3 protein tyrosine kinase (TYRO3) |
CNY 11,376.00 |
|
| SC108283 | TYRO3 (untagged)-Human TYRO3 protein tyrosine kinase (TYRO3) |
CNY 9,784.00 |
