ILRUN (NM_024294) Human Tagged ORF Clone
CAT#: RC209929
C6orf106 (Myc-DDK-tagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1
ORF Plasmid: tGFP
"NM_024294" in other vectors (5)
Need custom modification / cloning service?
Get a free quote
CNY 2,400.00
CNY 3,990.00
Cited in 3 publications. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | C6orf106; dJ391O22.4; FP852 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC209929 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGGCATGGACGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACA AGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTT CCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTTTGAGAGCCCAAACATC AGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTC AGTTTGTAAAAACATGGCGGATCCAGAATTCTGGGGCAGAGGCCTGGCCTCCAGGGGTTTGTCTTAAATA TGTCGGGGGAGACCAATTTGGACATGTGAACATGGTGATGGTGAGATCGCTAGAGCCCCAAGAGATTGCA GATGTCAGCGTCCAGATGTGCAGCCCCAGCAGAGCAGGAATGTATCAGGGACAGTGGCGGATGTGCACTG CTACAGGACTCTACTATGGAGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGT AACGCAGCAGCTGTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTC AACCCTTTTGCCTCTCCCCAAAAGAACCGACAATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCG AGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACACATGGGCTCCTGCTCCTGACCAAAC TGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAACTTA TCAGTAGTGACTTACAGTAAGGGGCTCCATGGGCCTTACCCCTTCGGCCAGTCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC209929 protein sequence
Red=Cloning site Green=Tags(s) MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNI SVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQFGHVNMVMVRSLEPQEIA DVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNF NPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNL SVVTYSKGLHGPYPFGQS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_024294 |
ORF Size | 894 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_024294.4 |
RefSeq Size | 4433 bp |
RefSeq ORF | 897 bp |
Locus ID | 64771 |
UniProt ID | Q9H6K1 |
MW | 32.9 kDa |
Gene Summary | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199).[UniProtKB/Swiss-Prot Function] |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
---|
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway
,Li, X;Dong, M;Zhou, J;Zhu, D;Zhao, J;Sheng, W;,
Mol. Cell. Biochem.
,PubMed ID 30311108
[ILRUN]
|
A novel biomarker C6orf106 promotes the malignant progression of breast cancer
,Jiang, G;Zhang, X;Zhang, Y;Wang, L;Fan, C;Xu, H;Miao, Y;Wang, E;,
Tumour Biol.
,PubMed ID 25953261
[ILRUN]
|
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn
,Zhang, X;Miao, Y;Yu, X;Zhang, Y;Jiang, G;Liu, Y;Yu, J;Han, Q;Zhao, H;Wang, E;,
Tumour Biol.
,PubMed ID 25736925
[ILRUN]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC209929L3 | Lenti ORF clone of Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC209929L4 | Lenti ORF clone of Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG209929 | C6orf106 (tGFP-tagged) - Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 |
CNY 4,000.00 |
|
SC112260 | C6orf106 (untagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 |
CNY 6,270.00 |
|
SC322752 | C6orf106 (untagged)-Human chromosome 6 open reading frame 106 (C6orf106), transcript variant 1 |
CNY 2,400.00 |