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Cannabinoid Receptor II (CNR2) (NM_001841) Human Tagged ORF Clone
CAT＃: RC210224
CNR2 (Myc-DDK-tagged)-Human cannabinoid receptor 2 (macrophage) (CNR2)
ORF Plasmid: tGFP
"NM_001841" in other vectors (6)
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CNY 5,488.00
| Cited in 7 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CB-2; CB2; CX5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC210224 representing NM_001841
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGAATGCTGGGTGACAGAGATAGCCAATGGCTCCAAGGATGGCTTGGATTCCAACCCTATGAAGG ATTACATGATCCTGAGTGGTCCCCAGAAGACAGCTGTTGCTGTGTTGTGCACTCTTCTGGGCCTGCTAAG TGCCCTGGAGAACGTGGCTGTGCTCTATCTGATCCTGTCCTCCCACCGGCTCCGCCGGAAGCCCTCATAC CTGTTCATTGGCAGCTTGGCTGGGGCTGACTTCCTGGCCAGTGTGGTCTTTGCATGCAGCTTTGTGAATT TCCATGTTTTCCATGGTGTGGATTCCAAGGCTGTCTTCCTGCTGAAGATTGGCAGCGTGACTATGACCTT CACAGCCTCTGTGGGTAGCCTCCTGCTGACCGCCATTGACCGATACCTCTGCCTGCGCTATCCACCTTCC TACAAAGCTCTGCTCACCCGTGGAAGGGCACTGGTGACCCTGGGTATCATGTGGGTCCTCTCAGCACTAG TCTCCTACCTGCCCCTCATGGGATGGACTTGCTGTCCCAGGCCCTGCTCTGAGCTTTTCCCACTGATCCC CAATGACTACCTGCTGAGCTGGCTCCTGTTCATCGCCTTCCTCTTTTCCGGAATCATCTACACCTATGGG CATGTTCTCTGGAAGGCCCATCAGCATGTAGCCAGCTTGTCTGGCCACCAGGACAGGCAGGTGCCAGGAA TGGCCCGAATGAGGCTGGATGTGAGGTTGGCCAAGACCCTAGGGCTAGTGCTGGCTGTGCTCCTCATCTG TTGGTTCCCAGTGCTGGCCCTCATGGCCCACAGCCTGGCCACTACGCTCAGTGACCAGGTCAAGAAGGCC TTTGCCTTCTGCTCCATGCTGTGCCTCATCAACTCCATGGTCAACCCTGTCATCTATGCTCTACGGAGTG GAGAGATCCGCTCCTCTGCCCATCACTGCCTGGCTCACTGGAAGAAGTGTGTGAGGGGCCTTGGGTCAGA GGCAAAAGAAGAAGCCCCAAGATCCTCAGTCACGGAGACAGAGGCTGATGGGAAAATCACTCCGTGGCCA GATTCCAGAGATCTAGACCTCTCTGATTGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC210224 representing NM_001841
Red=Cloning site Green=Tags(s) MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHRLRRKPSY LFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPS YKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYG HVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKA FAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWP DSRDLDLSDC TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001841 |
| ORF Size | 1080 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001841.3 |
| RefSeq Size | 1776 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 1269 |
| UniProt ID | P34972 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| MW | 39.5 kDa |
| Gene Summary | The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008] |
Citations (7)
| The use of this cDNA Clones has been cited in the following citations: |
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Rotenoids and Other Specialized Metabolites from the Roots of Mirabilis multiflora: Opioid and Cannabinoid Receptor Radioligand Binding Affinities
,Sharma, VK;Srivedavyasasri, R;Ali, Z;Zjawiony, JK;Ross, SA;Ferreira, D;Ashpole, N;Khan, IA;,
Journal of natural products
,PubMed ID 33734684
[Cannabinoid Receptor II]
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Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists
,Pandey, P;Roy, KK;Liu, H;Ma, G;Pettaway, S;Alsharif, WF;Gadepalli, RS;Rimoldi, JM;McCurdy, CR;Cutler, SJ;Doerksen, RJ;,
Molecules
,PubMed ID 30322136
[Cannabinoid Receptor II]
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Secondary metabolites isolated fromPinus roxburghiiand interpretation of their cannabinoid and opioid binding properties by virtual screening andin vitrostudies
,Labib, RM;Srivedavyasasri, R;Youssef, FS;Ross, SA;,
Saudi Pharm J
,PubMed ID 29556136
[Cannabinoid Receptor II]
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Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability
,Adelli, GR;Bhagav, P;Taskar, P;Hingorani, T;Pettaway, S;Gul, W;ElSohly, MA;Repka, MA;Majumdar, S;,
Invest. Ophthalmol. Vis. Sci.
,PubMed ID 28399267
[Cannabinoid Receptor II]
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Topical cannabinoid receptor 1 agonist attenuates the cutaneous inflammatory responses in oxazolone-induced atopic dermatitis model
,Kim, HJ;Kim, B;Park, BM;Jeon, JE;Lee, SH;Mann, S;Ahn, SK;Hong, SP;Jeong, SK;,
Int. J. Dermatol.
,PubMed ID 26095080
[Cannabinoid Receptor II]
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Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors
,Tarawneh, A;León, F;Pettaway, S;Elokely, KM;Klein, ML;Lambert, J;Mansoor, A;Cutler, SJ;,
J. Nat. Prod.
,PubMed ID 26035635
[Cannabinoid Receptor II]
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CXC Chemokine Receptor 4 Is a Cell Surface Receptor for Extracellular Ubiquitin *
,null,
The Journal of Biological Chemistry
,PubMed ID 20228059
[Cannabinoid Receptor II]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210224L1 | Lenti ORF clone of Human cannabinoid receptor 2 (macrophage) (CNR2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210224L2 | Lenti ORF clone of Human cannabinoid receptor 2 (macrophage) (CNR2), mGFP tagged |
CNY 5,890.00 |
|
| RC210224L3 | Lenti ORF clone of Human cannabinoid receptor 2 (macrophage) (CNR2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210224L4 | Lenti ORF clone of Human cannabinoid receptor 2 (macrophage) (CNR2), mGFP tagged |
CNY 7,888.00 |
|
| RG210224 | CNR2 (tGFP-tagged) - Human cannabinoid receptor 2 (macrophage) (CNR2) |
CNY 7,088.00 |
|
| SC118984 | CNR2 (untagged)-Human cannabinoid receptor 2 (macrophage) (CNR2) |
CNY 5,488.00 |
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