JMJD1C (NM_032776) Human Tagged ORF Clone
CAT#: RC214878
- TrueORF®
JMJD1C (Myc-DDK-tagged)-Human jumonji domain containing 1C (JMJD1C), transcript variant 1
ORF Plasmid: tGFP
"NM_032776" in other vectors (2)
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CNY 16,768.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | KDM3C; TRIP-8; TRIP8 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC214878 representing NM_032776
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGTAGAGACGCGGGCAGAGCTGGTGGGTAAGCGGTTCCTGTGTGTGGCGGTCGGCGACGAGGCAC GTTCGGAGCGCTGGGAGAGCGGACGCGGCTGGCGAAGCTGGCGAGCGGGGGTCATCCGAGCCGTGTCACA CAGGGACAGCCGCAATCCGGACCTGGCGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAG TGGGTTAAAGTTTATGAAGATTTTTCAACTTTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAATG ACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAACCTCTGGT TGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACT GAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGC AGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTA TTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGTGGTTTACTGGCATAATT ACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCG ATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGG CATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCC CAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACACACCAGCAAC AGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCAGATGAAGAGAAGAT GAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACACTTGATGAAT AAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAG ACTTTTCTGAGAGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCC AGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAG AAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGATAAAAAACATG AAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACA GTCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACC ATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCACACCAAAATGTGTTATTGATATTACAA ATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTCAGAAAAT GGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGAT TCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTT CAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTC TGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAATCTAAACTTAATACTTCA GTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTG ATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGAT AGAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAG AGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATTGGGTCAGAAA CAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCCTCATCTCATAGAAC CTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGT CAAACTCCATTACCTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTC ATTTACTTCCCACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAG TGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAG TCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTT GGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGA AAATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCT GTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATC GGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATAAGGAAGA ATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGAT CTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGT TACAGAGGCCACCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCGTCGAATTCTTCA AGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCC AGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAG TATCAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATT GTCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGAT AAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCTTT CAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAGAACATCT TCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACA GTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCC ATCACAGCCTGGAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCC AGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCC CAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCA AAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGT GCGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGAGTTAGT GAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAA TCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTGTCTCACA GGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACA TCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCA TTTTGGCCTCTACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGA ATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGT TCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGT ATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCC TCTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAG ACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGATAAAA ATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCAACTTAAT AGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTAAAAGAT GATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAA GTGAAAGCAAGTCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTT GCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAA AGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAAGATTGGCGTA AAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAA TTTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTA TTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTTCT CTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATGATGAACT AGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAA AAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGG AGATGTGTGATGCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGT CTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAACTATATGCTTGGATGAAG TGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGA CAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAA CAAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTT AATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCGAAGTCTGAGA AAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCTCCAGAATCCCAGTC ACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAACAAAGAACTT ACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCAC CTCTTGTGTCCCAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCT ACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAA AGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAAATTCCACCAA GTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGT GGATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTT AAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGTGG TTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATTTTGGAGA CCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGAT GGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACT GGCCTTCAGGAGAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATT GCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCT GATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAA ATCTCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCAT TCTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTG AAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAGGG AATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGATCCAATACGTGACCA AAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTT ATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCT GTATTCAGGTAACTGAAGATTTTGTGTCTCCAGAACATCTTGTAGAGTCATTTCATTTAACACAGGAACT GAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATATTTTGTATCATGCAGTC AAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC214878 representing NM_032776
Red=Cloning site Green=Tags(s) MAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKRE WVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLT EDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGII THHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRA QANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMN KRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNE KAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHT MELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKD SDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTS VDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTK SPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSS QTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQ SPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTP VTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLD LNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYS RVASSSSSPKSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGD KQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLT VSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDS QANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVS ERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVIT SAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPS SGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQ TSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKD DKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKE RSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPV FCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSE KTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMK CVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVL NHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKEL TLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSK SGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWL KDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWD GFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRP DLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRL KDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTL IQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILYHAV KEMVRALKIHEDEVEDMEEN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_032776 |
ORF Size | 7620 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_032776.2, NP_116165.1 |
RefSeq Size | 8786 bp |
RefSeq ORF | 7623 bp |
Locus ID | 221037 |
UniProt ID | Q15652 |
Protein Families | Druggable Genome |
MW | 285 kDa |
Gene Summary | The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis
,Viscarra, JA;Wang, Y;Nguyen, HP;Choi, YG;Sul, HS;,
Nat Commun
,PubMed ID 32034158
[JMJD1C]
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