Collagen VI (COL6A3) (NM_057164) Human Tagged Lenti ORF Clone
CAT#: RC216918L3
- LentiORF®
Lenti-ORF clone of COL6A3 (Myc-DDK-tagged)-Human collagen, type VI, alpha 3 (COL6A3), transcript variant 2
"NM_057164" in other vectors (4)
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CNY 12,260.00
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CNY 600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | BTHLM1; DYT27; UCMD1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC216918).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_057164 |
ORF Size | 3108 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_057164.4 |
RefSeq Size | 3485 bp |
RefSeq ORF | 3111 bp |
Locus ID | 1293 |
UniProt ID | P12111 |
Protein Families | Druggable Genome |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
MW | 113.2 kDa |
Gene Summary | This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC216918 | COL6A3 (Myc-DDK-tagged)-Human collagen, type VI, alpha 3 (COL6A3), transcript variant 2 |
CNY 10,360.00 |
|
RC216918L4 | Lenti-ORF clone of COL6A3 (mGFP-tagged)-Human collagen, type VI, alpha 3 (COL6A3), transcript variant 2 |
CNY 12,260.00 |
|
RG216918 | COL6A3 (tGFP-tagged) - Human collagen, type VI, alpha 3 (COL6A3), transcript variant 2 |
CNY 11,400.00 |
|
SC305744 | COL6A3 (untagged)-Human collagen, type VI, alpha 3 (COL6A3), transcript variant 2 |
CNY 20,050.00 |
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