Neurexin II alpha (NRXN2) (NM_015080) Human Tagged ORF Clone
CAT#: RC219788
NRXN2 (Myc-DDK-tagged)-Human neurexin 2 (NRXN2), transcript variant alpha-1
ORF Plasmid: tGFP
"NM_015080" in other vectors (4)
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CNY 11,512.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC219788 representing NM_015080
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTGGCGCTGGCGG CGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGCTACGCGCGCTGGGCGGGCGC GGCGAGCAGCGGCGAGCTCAGCTTCAGCCTGCGCACCAACGCCACGCGCGCGCTGCTGCTCTACCTGGAC GACGGCGGCGACTGCGACTTCCTGGAGCTGCTGCTGGTGGACGGCCGCCTGCGGCTGCGCTTCACGCTTT CGTGCGCCGAGCCGGCCACGCTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCT GACCCGCGACGCGCGCCGCACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAG CGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGCCCGACGTGCGCCTCTCGGCGC TTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCCAACCTGAAGCTGGGCGAGCG GCCCCCCGCGCTGCTGGGCAGCCAGGGCCTGCGCGGCGCCACCGCCGACCCGCTGTGCGCGCCCGCGCGC AACCCCTGCGCCAACGGCGGCCTCTGCACCGTGCTGGCCCCCGGCGAGGTGGGCTGCGACTGCAGCCACA CGGGCTTCGGCGGCAAGTTCTGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAAA CAGCGAAGTAGGGTCCTTACTGTTCTCCGAGGGGGGGGCCGGGAGAGGAGGAGCCGGCGATGTGCACCAG CCAACAAAAGGCAAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCAC ACAACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACCCTGCAACGCAACGGCCTGAT GCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGGGCTGTCTGGCTGGTCATC AACCTAGGCTCAGGTGCCTTCGAGGCCCTTGTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGC ACGACGTCCGGGTCACCCGAAACCTGCGCCAGCACGCAGGGATTGGACACGCTATGGTAAACAAACTGCA TTATCTGGTGACCATCTCGGTGGACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATG CTGGGCTCTGATGACTTCTTCTACATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCA GCAACAACTTCATGGGCTGCCTCAAGGACGTGGTCTATAAGAACAATGACTTCAAATTGGAACTATCCCG CCTGGCAAAGGAAGGGGACCCCAAGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGGATGTGGCT GCCCTGGACCCTGTGACCTTTGAGAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCA CTGGCTCCATCTCCCTAGACTTCCGCACCACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCG GGCTGGGGGTGGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCCGACTACTTTGCCATGGAGCTATTGGAC GGCCACCTCTATCTTCTGCTGGACATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCA ATGATGGCGAGTGGTGTCACGTGGACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCG CAGCACGCCGTTCTTGGCCACTGGAGACAGCGAGATTCTGGACCTGGAGAGTGAGCTGTACCTGGGCGGT CTCCCTGAGGGGGGCCGGGTGGACCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCT ACGTGGGCTGTGTGCGGGACCTCTTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCA GGGGGCTGTGGGCGTTGCCCCCTTTTGCTCCCGGGAGACGCTGAAGCAGTGTGCATCTGCCCCCTGTCGC AATGGGGGCGTCTGTCGAGAAGGCTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGCTTTCTTGGGC GGGTCTGTGAGAGAGAGGCCACGGTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAA CGCCATGCACACGGAGGCAGAGGATGTGTCCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATG GCCACCACTTCCAGGGAGTCTGCCGACACCCTACGCCTGGAGCTGGATGGGGGGCAGATGAAGCTCACTG TCAACCTCGACTGCCTGCGCGTCGGCTGCGCACCCAGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAA GCTCAATGACAATGAGTGGCACACGGTGAGGGTGGTCCGGCGTGGCAAGAGCCTGCAGCTGTCTGTGGAC AACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTTCCACAACATTGAGACGGGCA TCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGGCATCTGAGTGGGCTCGTGTT CAATGGCCAGCCCTACATGGACCAGTGCAAGGATGGTGACATCACCTACTGTGAGCTCAATGCTCGCTTT GGCCTGCGTGCCATCGTGGCCGATCCCGTCACCTTCAAGAGTCGCAGCAGCTACCTGGCACTCGCCACGC TCCAAGCCTATGCTTCCATGCACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGTT CAACTCGGGCAACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGAC CTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCAATGACAACCAGTGGCACAACG TGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCCCGCACTGTCACGCAGCACTC CAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTACATTGGCGGTCTGAGCAAGAATATGTTCAGC AACCTGCCCAAGCTGGTGGCCTCCCGGGATGGCTTTCAGGGCTGCCTGGCCTCAGTGGACCTCAACGGAC GTCTCCCAGACCTCATCGCCGACGCCCTGCACCGCATTGGGCAGGTGGAGAGGGGCTGTGATGGCCCCAG CACCACCTGCACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGC GACTGCACCATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGACCACATACATCTTTGGGAAGG GGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACGAGGATGGATCGCCTGGCCGT GGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAGCGCCTCCGGCCTTGGAGACTAC CTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCG ACGAGCCCAACGCCATAGTAAGCGACGGCAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGC CACCCTGCAGGTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATAACGAGCGCCTG GCGATTGCTAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAGATGAGTGGCTGCTCGACAAAGGCC GCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCA GGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGAGCGACCCCAAT GTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGG CCACCACCCTGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCAC GCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCT GCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGC CCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCC TACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGC CCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCGG GCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTT TCCCCTGGTCACGGACCGCACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACA GATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGGCA AAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTC CTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCC ACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGGAGGTGATCCGGGAGTCCAGCA GCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCAT GTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCG GCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGA AGAACAAAGACAAGGAGTATTATGTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC219788 representing NM_015080
Red=Cloning site Green=Tags(s) MASGSRWRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALLLYLD DGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSK RREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAPAR NPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQ PTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVI NLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTM LGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVA ALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLD GHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGG LPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCR NGGVCREGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMM ATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVD NVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARF GLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGYIHYVFD LGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFS NLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTC DCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDY LQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERL AIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPN VRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS AECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRT DGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLP TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNS AQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_015080 |
ORF Size | 5136 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_015080.4 |
RefSeq Size | 6616 bp |
RefSeq ORF | 5139 bp |
Locus ID | 9379 |
UniProt ID | Q9P2S2 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 184.98 kDa |
Gene Summary | This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons
,Rizzo, F;Nizzardo, M;Vashisht, S;Molteni, E;Melzi, V;Taiana, M;Salani, S;Santonicola, P;Di Schiavi, E;Bucchia, M;Bordoni, A;Faravelli, I;Bresolin, N;Comi, GP;Pozzoli, U;Corti, S;,
Brain
,PubMed ID 30649277
[Neurexin II alpha]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219788L1 | Lenti ORF clone of Human neurexin 2 (NRXN2), transcript variant alpha-1, Myc-DDK-tagged |
CNY 13,912.00 |
|
RC219788L3 | Lenti ORF clone of Human neurexin 2 (NRXN2), transcript variant alpha-1, Myc-DDK-tagged |
CNY 19,000.00 |
|
RG219788 | NRXN2 (tGFP-tagged) - Human neurexin 2 (NRXN2), transcript variant alpha-1 |
CNY 18,810.00 |
|
SC319037 | NRXN2 (untagged)-Human neurexin 2 (NRXN2), transcript variant alpha-1 |
CNY 32,870.00 |
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