VE Cadherin (CDH5) (NM_001795) Human Tagged ORF Clone
CAT#: RC223907
- TrueORF®
CDH5 (Myc-DDK-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5)
ORF Plasmid: tGFP
"NM_001795" in other vectors (6)
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CNY 8,616.00
Cited in 2 publications. |
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | 7B4; CD144 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001795 |
ORF Size | 2352 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001795.5 |
RefSeq Size | 4134 bp |
RefSeq ORF | 2355 bp |
Locus ID | 1003 |
UniProt ID | P33151 |
Domains | Cadherin_C_term, CA |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration |
MW | 87.5 kDa |
Gene Summary | This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Vascular Endothelial-cadherin plays a role in regulating the Norrin-FZD4 pathway and can cause Familial Exududative-vitroretinopathy (FEVR)
,Amasheh, R;,
Thesis
[CDH5]
|
Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein
,null,
Nature methods
,PubMed ID 24633408
[CDH5]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC223907L1 | Lenti-ORF clone of CDH5 (Myc-DDK-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 10,170.00 |
|
RC223907L2 | Lenti-ORF clone of CDH5 (mGFP-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 10,170.00 |
|
RC223907L3 | Lenti-ORF clone of CDH5 (Myc-DDK-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 10,170.00 |
|
RC223907L4 | Lenti-ORF clone of CDH5 (mGFP-tagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 10,170.00 |
|
RG223907 | CDH5 (tGFP-tagged) - Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 10,216.00 |
|
SC119021 | CDH5 (untagged)-Human cadherin 5, type 2 (vascular endothelium) (CDH5) |
CNY 15,110.00 |
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