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GGCX (NM_001142269) Human Tagged ORF Clone
CAT＃: RC226869
- TrueORF®
GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2
ORF Plasmid: tGFP
"NM_001142269" in other vectors (4)
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CNY 5,800.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | VKCFD1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC226869 representing NM_001142269
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGTGTCTGCCGGGTCCGCGCGGACCTCGCCCAGCTCAGGGTTCTTGATGGTGCTAGACATTCCCC AGGAGCGGGGGCTCAGCTCTCTGGACCGGAAATACCTTGATGGGCTGGATGTGTGCCGCTTCCCCTTGCT GGATGCCCTACGCCCACTGCCACTTGACTGGATGTATCTTGTCTACACCATCATGTTTCTGGGGGCACTG GGCATGATGCTGGGCCTGTGCTACCGGATAAGCTGTGTGTTATTCCTGCTGCCATACTGGTATGTGTTTC TCCTGGACAAGACATCATGGAACAACCACTCCTATCTGTATGGGTTGTTGGCCTTTCAGCTAACATTCAT GGATGCAAACCACTACTGGTCTGTGGACGGTCTGCTGAATGCCCATAGGAGGAATGCCCACGTGCCCCTT TGGAACTATGCAGTGCTCCGTGGCCAGATCTTCATTGTGTACTTCATTGCGGGTGTGAAAAAGCTGGATG CAGACTGGGTTGAAGGCTATTCCATGGAATATTTGTCCCGGCACTGGCTCTTCAGTCCCTTCAAACTGCT GTTGTCTGAGGAGCTGACTAGCCTGCTGGTCGTGCACTGGGGTGGGCTGCTGCTTGACCTCTCAGCTGGT TTCCTGCTCTTTTTTGATGTCTCAAGATCCATTGGCCTGTTCTTTGTGTCCTACTTCCACTGCATGAATT CCCAGCTTTTCAGCATTGGTATGTTCTCCTACGTCATGCTGGCCAGCAGCCCTCTCTTCTGCTCCCCTGA GTGGCCTCGGAAGCTGGTGTCCTACTGCCCCCGAAGGTTGCAACAACTGTTGCCCCTCAAGGCAGCCCCT CAGCCCAGTGTTTCCTGTGTGTATAAGAGGAGCCGGGGCAAAAGTGGCCAGAAGCCAGGGCTGCGCCATC AGCTGGGAGCTGCCTTCACCCTGCTCTACCTCCTGGAGCAGCTATTCCTGCCCTATTCTCATTTTCTCAC CCAGGGCTATAACAACTGGACAAATGGGCTGTATGGCTATTCCTGGGACATGATGGTGCACTCCCGCTCC CACCAGCACGTGAAGATCACCTACCGTGATGGCCGCACTGGCGAACTGGGCTACCTTAACCCTGGGGTAT TTACACAGAGTCGGCGATGGAAGGATCATGCAGACATGCTGAAGCAATATGCCACTTGCCTGAGCCGCCT GCTTCCCAAGTATAATGTCACTGAGCCCCAGATCTACTTTGATATTTGGGTCTCCATCAATGACCGCTTC CAGCAGAGGATTTTTGACCCTCGTGTGGACATCGTGCAGGCCGCTTGGTCACCCTTTCAGCGCACATCCT GGGTGCAACCACTCTTGATGGACCTGTCTCCCTGGAGGGCCAAGTTACAGGAAATCAAGAGCAGCCTAGA CAACCACACTGAGGTGGTCTTCATTGCAGATTTCCCTGGACTGCACTTGGAGAATTTTGTGAGTGAAGAC CTGGGCAACACTAGCATCCAGCTGCTGCAGGGGGAAGTGACTGTGGAGCTTGTGGCAGAACAGAAGAACC AGACTCTTCGAGAGGGAGAAAAAATGCAGTTGCCTGCTGGTGAGTACCATAAGGTGTATACGACATCACC TAGCCCTTCTTGCTACATGTACGTCTATGTCAACACTACAGAGCTTGCACTGGAGCAAGACCTGGCATAT CTGCAAGAATTAAAGGAAAAGGTGGAGAATGGAAGTGAAACAGGGCCTCTACCCCCAGAGCTGCAGCCTC TGTTGGAAGGGGAAGTAAAAGGGGGCCCTGAGCCAACACCTCTGGTTCAGACCTTTCTTAGACGCCAACA AAGGCTCCAGGAGATTGAACGCCGGCGAAATACTCCTTTCCATGAGCGATTCTTCCGCTTCTTGTTGCGA AAGCTCTATGTCTTTCGCCGCAGCTTCCTGATGACTTGTATCTCACTTCGAAATCTGATATTAGGCCGTC CTTCCCTGGAGCAGCTGGCCCAGGAGGTGACTTATGCAAACTTGAGACCCTTTGAGGCAGTTGGAGAACT GAATCCCTCAAACACGGATTCTTCACATTCTAATCCTCCTGAGTCAAATCCTGATCCTGTCCACTCAGAG TTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC226869 representing NM_001142269
Red=Cloning site Green=Tags(s) MAVSAGSARTSPSSGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDALRPLPLDWMYLVYTIMFLGAL GMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLLNAHRRNAHVPL WNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSAG FLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAP QPSVSCVYKRSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRS HQHVKITYRDGRTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRF QQRIFDPRVDIVQAAWSPFQRTSWVQPLLMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSED LGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEYHKVYTTSPSPSCYMYVYVNTTELALEQDLAY LQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRLQEIERRRNTPFHERFFRFLLR KLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNPPESNPDPVHSE F TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001142269 |
| ORF Size | 2103 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001142269.4 |
| RefSeq Size | 7304 bp |
| RefSeq ORF | 2106 bp |
| Locus ID | 2677 |
| UniProt ID | P38435 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 81 kDa |
| Gene Summary | This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226869L3 | Lenti-ORF clone of GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 7,700.00 |
|
| RC226869L4 | Lenti-ORF clone of GGCX (mGFP-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 7,700.00 |
|
| RG226869 | GGCX (tGFP-tagged) - Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 6,370.00 |
|
| SC326185 | GGCX (untagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 2 |
CNY 13,490.00 |
