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PERP (NM_022121) Human Tagged ORF Clone
CAT＃: RG204012
- TrueORF®
PERP (tGFP-tagged) - Human PERP, TP53 apoptosis effector (PERP)
ORF Plasmid: DDK
"NM_022121" in other vectors (6)
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CNY 4,000.00
CNY 4,370.00
| Cited in 1 publication. |
Product images
CNY 1,000.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | dJ496H19.1; KCP1; KRTCAP1; PIGPC1; THW |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG204012 representing NM_022121
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATCCGCTGCGGCCTGGCCTGCGAGCGCTGCCGCTGGATCCTGCCCCTGCTCCTACTCAGCGCCATCG CCTTCGACATCATCGCGCTGGCCGGCCGCGGCTGGTTGCAGTCTAGCGACCACGGCCAGACGTCCTCGCT GTGGTGGAAATGCTCCCAAGAGGGCGGCGGCAGCGGGTCCTACGAGGAGGGCTGTCAGAGCCTCATGGAG TACGCGTGGGGTAGAGCAGCGGCTGCCATGCTCTTCTGTGGCTTCATCATCCTGGTGATCTGTTTCATCC TCTCCTTCTTCGCCCTCTGTGGACCCCAGATGCTTGTCTTCCTGAGAGTGATTGGAGGTCTCCTTGCCTT GGCTGCTGTGTTCCAGATCATCTCCCTGGTAATTTACCCCGTGAAGTACACCCAGACCTTCACCCTTCAT GCCAACCCTGCTGTCACTTACATCTATAACTGGGCCTACGGCTTTGGGTGGGCAGCCACGATTATCCTGA TTGGCTGTGCCTTCTTCTTCTGCTGCCTCCCCAACTACGAAGATGACCTTCTGGGCAATGCCAAGCCCAG GTACTTCTACACATCTGCC AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG204012 representing NM_022121
Red=Cloning site Green=Tags(s) MIRCGLACERCRWILPLLLLSAIAFDIIALAGRGWLQSSDHGQTSSLWWKCSQEGGGSGSYEEGCQSLME YAWGRAAAAMLFCGFIILVICFILSFFALCGPQMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFTLH ANPAVTYIYNWAYGFGWAATIILIGCAFFFCCLPNYEDDLLGNAKPRYFYTSA SGPTRTRRLE - GFP Tag - V |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_022121 |
| ORF Size | 579 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_022121.5 |
| RefSeq Size | 1941 bp |
| RefSeq ORF | 582 bp |
| Locus ID | 64065 |
| UniProt ID | Q96FX8 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | p53 signaling pathway |
| Gene Summary | Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells
,Khan, IA;Yoo, BH;Masson, O;Baron, S;Corkery, D;Dellaire, G;Attardi, LD;Rosen, KV;,
Oncogene
,PubMed ID 27109096
[PERP]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204012 | PERP (Myc-DDK-tagged)-Human PERP, TP53 apoptosis effector (PERP) |
CNY 2,400.00 |
|
| RC204012L1 | Lenti ORF clone of Human PERP, TP53 apoptosis effector (PERP), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204012L2 | Lenti ORF clone of Human PERP, TP53 apoptosis effector (PERP), mGFP tagged |
CNY 4,800.00 |
|
| RC204012L3 | Lenti ORF clone of Human PERP, TP53 apoptosis effector (PERP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204012L4 | Lenti ORF clone of Human PERP, TP53 apoptosis effector (PERP), mGFP tagged |
CNY 5,890.00 |
|
| SC112805 | PERP (untagged)-Human PERP, TP53 apoptosis effector (PERP) |
CNY 2,400.00 |
