MTA2 (NM_004739) Human Tagged ORF Clone
CAT#: RG208756
- TrueORF®
MTA2 (tGFP-tagged) - Human metastasis associated 1 family, member 2 (MTA2)
ORF Plasmid: DDK
"NM_004739" in other vectors (6)
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CNY 6,496.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | MTA1L1; PID |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG208756 representing NM_004739
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCCAACATGTACCGGGTGGGAGATTACGTCTATTTTGAGAACTCTTCCAGCAATCCTTACCTGG TTAGACGGATTGAGGAGCTCAACAAGACTGCAAATGGAAATGTGGAGGCAAAGGTTGTCTGTCTTTTCCG GCGCAGGGACATTTCTAGTAGCCTCAACAGCCTGGCTGATAGTAATGCCAGGGAGTTTGAAGAGGAATCA AAGCAGCCAGGGGTGTCTGAGCAGCAGCGCCATCAACTGAAGCACCGGGAACTTTTTCTTTCTCGGCAAT TTGAATCATTACCAGCCACCCACATACGGGGGAAATGCAGTGTGACCCTCTTGAATGAGACAGATATCTT GAGCCAGTACCTGGAAAAGGAGGACTGCTTTTTTTACTCACTGGTGTTTGACCCCGTGCAGAAGACACTT CTCGCTGATCAGGGCGAGATTAGAGTTGGTTGCAAATACCAAGCTGAGATCCCAGATCGCCTAGTAGAGG GAGAATCTGATAATCGGAACCAGCAGAAGATGGAGATGAAGGTCTGGGACCCAGACAACCCTCTCACAGA CCGGCAGATCGACCAGTTTCTTGTGGTGGCCCGAGCTGTGGGAACCTTTGCAAGAGCCCTAGATTGTAGC AGCTCCATTCGGCAGCCAAGCTTGCACATGAGTGCAGCTGCTGCCTCCCGAGATATCACTCTGTTTCACG CCATGGATACCTTGCAAAGGAACGGCTACGACCTGGCTAAGGCCATGTCGACCCTGGTACCCCAGGGAGG CCCGGTGCTGTGTCGGGATGAGATGGAGGAATGGTCAGCCTCAGAGGCCATGCTATTTGAGGAGGCCCTA GAGAAGTATGGGAAGGACTTCAATGATATTCGCCAGGATTTTCTACCCTGGAAGTCACTTGCCAGCATAG TCCAGTTTTATTACATGTGGAAAACCACAGACCGGTATATTCAGCAGAAAAGGTTGAAAGCTGCTGAAGC AGACAGCAAACTGAAACAGGTCTACATTCCCACCTACACTAAGCCAAACCCTAACCAGATCATTTCTGTG GGTTCAAAACCTGGCATGAATGGGGCTGGATTTCAGAAGGGCCTGACTTGTGAGAGTTGCCACACCACAC AGTCTGCTCAGTGGTATGCCTGGGGCCCACCTAACATGCAGTGCCGCCTCTGTGCTTCCTGTTGGATCTA CTGGAAGAAGTATGGGGGACTGAAGACCCCAACTCAGCTTGAGGGGGCCACTCGGGGCACCACGGAGCCA CACTCAAGGGGTCATTTATCCAGACCTGAAGCTCAAAGTCTCTCTCCTTACACAACCAGCGCCAACAGGG CCAAGCTACTGGCTAAGAACAGACAAACTTTCCTGCTTCAGACCACAAAGCTGACCCGTCTTGCCAGACG CATGTGCAGGGACCTATTACAGCCAAGGAGGGCCGCCCGACGGCCTTATGCTCCTATCAATGCCAATGCC ATCAAAGCAGAGTGCTCCATTCGACTTCCTAAGGCCGCCAAGACTCCATTGAAGATTCACCCTCTGGTGC GGCTGCCCCTGGCAACTATCGTCAAAGATCTGGTGGCCCAGGCACCCCTGAAACCAAAAACACCTCGGGG TACCAAGACACCGATCAACAGAAACCAGCTGTCCCAGAACCGGGGACTGGGGGGCATTATGGTGAAACGG GCCTATGAGACTATGGCAGGGGCAGGGGTTCCTTTCTCTGCCAATGGAAGGCCTCTGGCTTCAGGGATTC GTTCAAGCTCACAGCCAGCAGCCAAGCGTCAGAAACTAAACCCAGCTGATGCCCCCAATCCTGTGGTGTT TGTGGCCACAAAGGATACCAGGGCCCTACGGAAGGCTCTGACCCATCTGGAAATGCGGCGAGCTGCTCGC CGACCCAACTTGCCCCTGAAGGTGAAGCCAACGCTGATTGCAGTGCGGCCCCCTGTCCCTCTACCTGCAC CCTCACATCCTGCCAGCACCAATGAGCCTATTGTCCTGGAGGAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG208756 representing NM_004739
Red=Cloning site Green=Tags(s) MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLADSNAREFEEES KQPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDILSQYLEKEDCFFYSLVFDPVQKTL LADQGEIRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARALDCS SSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEAL EKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISV GSKPGMNGAGFQKGLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPTQLEGATRGTTEP HSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRLARRMCRDLLQPRRAARRPYAPINANA IKAECSIRLPKAAKTPLKIHPLVRLPLATIVKDLVAQAPLKPKTPRGTKTPINRNQLSQNRGLGGIMVKR AYETMAGAGVPFSANGRPLASGIRSSSQPAAKRQKLNPADAPNPVVFVATKDTRALRKALTHLEMRRAAR RPNLPLKVKPTLIAVRPPVPLPAPSHPASTNEPIVLED TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_004739 |
ORF Size | 2004 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_004739.4 |
RefSeq Size | 3060 bp |
RefSeq ORF | 2007 bp |
Locus ID | 9219 |
UniProt ID | O94776 |
Domains | GATA, ELM2, myb_DNA-binding, BAH |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208756 | MTA2 (Myc-DDK-tagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 4,896.00 |
|
RC208756L1 | Lenti-ORF clone of MTA2 (Myc-DDK-tagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 7,296.00 |
|
RC208756L2 | Lenti-ORF clone of MTA2 (mGFP-tagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 7,700.00 |
|
RC208756L3 | Lenti-ORF clone of MTA2 (Myc-DDK-tagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 7,700.00 |
|
RC208756L4 | Lenti-ORF clone of MTA2 (mGFP-tagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 7,700.00 |
|
SC117188 | MTA2 (untagged)-Human metastasis associated 1 family, member 2 (MTA2) |
CNY 4,904.00 |