IL1 Receptor I (IL1R1) (NM_000877) Human Tagged ORF Clone
CAT#: RG210412
- TrueORF®
IL1R1 (tGFP-tagged) - Human interleukin 1 receptor, type I (IL1R1)
ORF Plasmid: DDK
"NM_000877" in other vectors (6)
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CNY 5,840.00
Cited in 1 publication. |
CNY 1,000.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_000877 |
ORF Size | 1707 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000877.4 |
RefSeq Size | 4909 bp |
RefSeq ORF | 1710 bp |
Locus ID | 3554 |
UniProt ID | P14778 |
Domains | TIR, IG |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway |
Gene Summary | This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Endogenous production of IL-1B by breast cancer cells drives metastasis and colonisation of the bone microenvironment
,Tulotta, C;Lefley, DV;Freeman, K;Gregory, WM;Hanby, AM;Heath, PR;Nutter-Howard, F;Wilkinson, JM;Spicer-Hadlington, AR;Liu, X;Bradbury, S;Hambley, L;Cookson, V;Allocca, G;Kruithof-de-Julio, M;Coleman, RE;Brown, JE;Holen, I;Ottewell, PD;,
Clin. Cancer Res.
,PubMed ID 30670488
[IL1R1]
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Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC210412 | IL1R1 (Myc-DDK-tagged)-Human interleukin 1 receptor, type I (IL1R1) |
CNY 4,240.00 |
|
RC210412L1 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), Myc-DDK-tagged |
CNY 6,640.00 |
|
RC210412L2 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), mGFP tagged |
CNY 6,460.00 |
|
RC210412L3 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), Myc-DDK-tagged |
CNY 6,640.00 |
|
RC210412L4 | Lenti ORF clone of Human interleukin 1 receptor, type I (IL1R1), mGFP tagged |
CNY 6,460.00 |
|
SC119624 | IL1R1 (untagged)-Human interleukin 1 receptor, type I (IL1R1) |
CNY 4,248.00 |
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