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TRIF (TICAM1) (NM_182919) Human Tagged ORF Clone
CAT＃: RG217522
- TrueORF®
TICAM1 (tGFP-tagged) - Human toll-like receptor adaptor molecule 1 (TICAM1)
ORF Plasmid: DDK
"NM_182919" in other vectors (4)
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CNY 6,816.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG217522 representing NM_182919.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCCTGCACAGGCCCATCACTTCCTAGCGCCTTCGACATTCTAGGTGCAGCAGGCCAGGACAAGCTC TTGTATCTGAAGCACAAACTGAAGACCCCACGCCCAGGCTGCCAGGGGCAGGACCTCCTGCATGCCATG GTTCTCCTGAAGCTGGGCCAGGAAACTGAGGCCAGGATCTCTCTAGAGGCATTGAAGGCCGATGCGGTG GCCCGGCTGGTGGCCCGCCAGTGGGCTGGCGTGGACAGCACCGAGGACCCAGAGGAGCCCCCAGATGTG TCCTGGGCTGTGGCCCGCTTGTACCACCTGCTGGCTGAGGAGAAGCTGTGCCCCGCCTCGCTGCGGGAC GTGGCCTACCAGGAAGCCGTCCGCACCCTCAGCTCCAGGGACGACCACCGGCTGGGGGAACTTCAGGAT GAGGCCCGAAACCGGTGTGGGTGGGACATTGCTGGGGATCCAGGGAGCATCCGGACGCTCCAGTCCAAT CTGGGCTGCCTCCCACCATCCTCGGCTTTGCCCTCTGGGACCAGGAGCCTCCCACGCCCCATTGACGGT GTTTCGGACTGGAGCCAAGGGTGCTCCCTGCGATCCACTGGCAGCCCTGCCTCCCTGGCCAGCAACTTG GAAATCAGCCAGTCCCCTACCATGCCCTTCCTCAGCCTGCACCGCAGCCCACATGGGCCCAGCAAGCTC TGTGACGACCCCCAGGCCAGCTTGGTGCCCGAGCCTGTCCCCGGTGGCTGCCAGGAGCCTGAGGAGATG AGCTGGCCGCCATCGGGGGAGATTGCCAGCCCACCAGAGCTGCCAAGCAGCCCACCTCCTGGGCTTCCC GAAGTGGCCCCAGATGCAACCTCCACTGGCCTCCCTGATACCCCCGCAGCTCCAGAAACCAGCACCAAC TACCCAGTGGAGTGCACCGAGGGGTCTGCAGGCCCCCAGTCTCTCCCCTTGCCTATTCTGGAGCCGGTC AAAAACCCCTGCTCTGTCAAAGACCAGACGCCACTCCAACTTTCTGTAGAAGATACCACCTCTCCAAAT ACCAAGCCGTGCCCACCTACTCCCACCACCCCAGAAACATCCCCTCCTCCTCCTCCTCCTCCTCCTTCA TCTACTCCTTGTTCAGCTCACCTGACCCCCTCCTCCCTGTTCCCTTCCTCCCTGGAATCATCATCGGAA CAGAAATTCTATAACTTTGTGATCCTCCACGCCAGGGCAGACGAACACATCGCCCTGCGGGTTCGGGAG AAGCTGGAGGCCCTTGGCGTGCCCGACGGGGCCACCTTCTGCGAGGATTTCCAGGTGCCGGGGCGCGGG GAGCTGAGCTGCCTGCAGGACGCCATAGACCACTCAGCTTTCATCATCCTACTTCTCACCTCCAACTTC GACTGTCGCCTGAGCCTGCACCAGGTGAACCAAGCCATGATGAGCAACCTCACGCGACAGGGGTCGCCA GACTGTGTCATCCCCTTCCTGCCCCTGGAGAGCTCCCCGGCCCAGCTCAGCTCCGACACGGCCAGCCTG CTCTCCGGGCTGGTGCGGCTGGACGAACACTCCCAGATCTTCGCCAGGAAGGTGGCCAACACCTTCAAG CCCCACAGGCTTCAGGCCCGAAAGGCCATGTGGAGGAAGGAACAGGACACCCGAGCCCTGCGGGAACAG AGCCAACACCTGGATGGTGAGCGGATGCAGGCGGCGGCACTGAACGCAGCCTACTCAGCCTACCTCCAG AGCTACTTGTCCTACCAGGCACAGATGGAGCAGCTCCAGGTGGCTTTTGGGAGCCACATGTCATTTGGG ACTGGGGCGCCCTATGGGGCTCGAATGCCCTTTGGGGGCCAGGTGCCCCTGGGAGCCCCGCCACCCTTT CCCACTTGGCCGGGGTGCCCGCAGCCGCCACCCCTGCACGCATGGCAGGCTGGCACCCCCCCACCGCCC TCCCCACAGCCAGCAGCCTTTCCACAGTCACTGCCCTTCCCGCAGTCCCCAGCCTTCCCTACGGCCTCA CCCGCACCCCCTCAGAGCCCAGGGCTGCAACCCCTCATTATCCACCACGCACAGATGGTACAGCTGGGG CTGAACAACCACATGTGGAACCAGAGAGGGTCCCAGGCGCCCGAGGACAAGACGCAGGAGGCAGAA ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG217522
Blue=ORF Red=Cloning site Green=Tag(s) MACTGPSLPSAFDILGAAGQDKLLYLKHKLKTPRPGCQGQDLLHAMVLLKLGQETEARISLEALKADAV ARLVARQWAGVDSTEDPEEPPDVSWAVARLYHLLAEEKLCPASLRDVAYQEAVRTLSSRDDHRLGELQD EARNRCGWDIAGDPGSIRTLQSNLGCLPPSSALPSGTRSLPRPIDGVSDWSQGCSLRSTGSPASLASNL EISQSPTMPFLSLHRSPHGPSKLCDDPQASLVPEPVPGGCQEPEEMSWPPSGEIASPPELPSSPPPGLP EVAPDATSTGLPDTPAAPETSTNYPVECTEGSAGPQSLPLPILEPVKNPCSVKDQTPLQLSVEDTTSPN TKPCPPTPTTPETSPPPPPPPPSSTPCSAHLTPSSLFPSSLESSSEQKFYNFVILHARADEHIALRVRE KLEALGVPDGATFCEDFQVPGRGELSCLQDAIDHSAFIILLLTSNFDCRLSLHQVNQAMMSNLTRQGSP DCVIPFLPLESSPAQLSSDTASLLSGLVRLDEHSQIFARKVANTFKPHRLQARKAMWRKEQDTRALREQ SQHLDGERMQAAALNAAYSAYLQSYLSYQAQMEQLQVAFGSHMSFGTGAPYGARMPFGGQVPLGAPPPF PTWPGCPQPPPLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAFPTASPAPPQSPGLQPLIIHHAQMVQLG LNNHMWNQRGSQAPEDKTQEAE TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_182919 |
| ORF Size | 2136 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq Size | 2460 bp |
| RefSeq ORF | 2139 bp |
| Locus ID | 148022 |
| UniProt ID | Q8IUC6 |
| Protein Families | Druggable Genome |
| Protein Pathways | Toll-like receptor signaling pathway |
| MW | 76.4 kDa |
| Gene Summary | This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced. [provided by RefSeq, Jul 2020] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation
,Xiong, D;Song, L;Geng, S;Jiao, Y;Zhou, X;Song, H;Kang, X;Zhou, Y;Xu, X;Sun, J;Pan, Z;Jiao, X;,
Cell Rep
,PubMed ID 31315056
[TICAM1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217522 | TICAM1 (Myc-DDK-tagged)-Human toll-like receptor adaptor molecule 1 (TICAM1) |
CNY 5,216.00 |
|
| RC217522L3 | Lenti ORF clone of Human toll-like receptor adaptor molecule 1 (TICAM1), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC217522L4 | Lenti ORF clone of Human toll-like receptor adaptor molecule 1 (TICAM1), mGFP tagged |
CNY 7,700.00 |
|
| SC120956 | TICAM1 (untagged)-Human toll-like receptor adaptor molecule 1 (TICAM1) |
CNY 5,224.00 |
