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PGC1 beta (PPARGC1B) (NM_001172699) Human Tagged ORF Clone
CAT＃: RG230594
- TrueORF®
PPARGC1B (tGFP-tagged) - Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 3
ORF Plasmid: DDK
"NM_001172699" in other vectors (4)
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CNY 10,740.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ERRL1; PERC; PGC-1(beta); PGC1B |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG230594 representing NM_001172699
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCAGCTGGATG CCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAGCTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACC CAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGACAGTGAGAATGAGGCCCTCCTGGCAGAG CTCACCAAGACCCTGGATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTG GAGACGCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAA GCCCTCGGCCCCAGCCCCTGAGGTGGACGAGCTCTCACTGGCGGACAGCACCCAAGACAAGAAGGCTCCC ATGATGCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTGCCTGC AGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCCCTGCCAAGGAGGACAAGGAGCCGGG TGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAGGGCAGAC CCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACT GCCTCCCCCAGAGGAAGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCA GCAGGTCAGATCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGG GAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCACGCCTGTTTATGCCT CCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGT GGAGGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTG GAGGTGAAAAGGGAGGTCCGCCGGCCTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGG AGGAGGAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCC ATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGAACCCT GAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCTGCCCT CACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGG CCAAGACCAGCAGCTCCTACGGGGACCCCAGATCCCTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGG GACATGGATGAGGACCCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCT TGTCACAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCAC AGCAGGACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATC AAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGCCACCC CAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTGAGCTCCTGTCCCACCTGCGACATGC CACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCATGACTAC TGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTC ACCTTGAGGACTGGCCCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAG AAGCTGTGATGCTGGCGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTC ACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCTGCAAGAGCCCTGAGT ATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGA AGAAGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCAC TGCCCCTACCAGAGCCCACCAAGCAAGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCT CTTCACCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTC AGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCGTGGTG TACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGGTGAGA TTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCATCACCTACCGGTGTTC TGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTGCCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTG AGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAGATACACTGACTACGATTCCAATTCAGAAGAGGCCC TTCCTGCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAG CCTGCAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG230594 representing NM_001172699
Red=Cloning site Green=Tags(s) MGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEALLAE LTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLADSTQDKKAP MMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRAD PGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILR ELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRL EVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNP ELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCG DMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDI KHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDY CQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASL TKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDH CPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVV YIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQL SYGGLRHFCWPRYTDYDSNSEEALPASGKSKYEAMDFDSLLKEAQQSLH TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001172699 |
| ORF Size | 2877 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001172699.1, NP_001166170.1 |
| RefSeq Size | 10556 bp |
| RefSeq ORF | 2880 bp |
| Locus ID | 133522 |
| UniProt ID | Q86YN6 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels
,null,
Autophagy
,PubMed ID 31032705
[PPARGC1B]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC230594 | PPARGC1B (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 3 |
CNY 9,790.00 |
|
| RC230594L3 | Lenti-ORF clone of PPARGC1B (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 3 |
CNY 11,690.00 |
|
| RC230594L4 | Lenti-ORF clone of PPARGC1B (mGFP-tagged)-Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 3 |
CNY 11,690.00 |
|
| SC329232 | PPARGC1B (untagged)-Human peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1B) transcript variant 3 |
CNY 18,530.00 |
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