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LONP2 (NM_001300948) Human Tagged ORF Clone
CAT＃: RG239606
- TrueORF®
LONP2 (tGFP-tagged) - Human lon peptidase 2, peroxisomal (LONP2), transcript variant 2
ORF Plasmid: DDK
"NM_001300948" in other vectors (2)
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CNY 6,180.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | LONP; LONPL; PLON; PSLON |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239606 representing NM_001300948.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCATCAGTGAGCCCCATCCAGATCCCCAGTCGCCTCCCGCTGCTGCTCACCCACGAGGGCGTCCTG CTGCCCGGCTCCACCATGCGCACCAGCGTGGACTCGGCCCGCAACCTGCAGCTGGTGCGGAGCCGCCTT CTGAAGGGCACGTCGCTGCAAAGCACCATCCTGGGCGTCATCCCCAACACGCCTGACCCCGCCAGCGAC GCGCAGGACCTGCCGCCGCTGCACAGGATTGGCACAGCTGCACTGGCCGTTCAGGTTGTGGGCAGTAAC TGGCCCAAGCCCCACTACACTCTGTTGATTACAGGCCTATGCCGTTTCCAGATTGTACAGGTCTTAAAA GAGAAGCCATATCCCATTGCTGAAGTGGAGCAGTTGGACCGACTTGAGGAGTTTCCCAACACCTGTAAA ATGAGGGAGGAGCTAGGAGAACTATCAGAGCAGTTTTACAAATATGCAGTACAAATTTTAGATGCTGTG AGCCTAGAGGAGCGGTTCAAGATGACTATACCACTGCTTGTCAGACAAATTGAAGGCCTGAAATTGCTT CAAAAAACCAGAAAACCCAAGCAAGATGATGATAAGAGGGTTATAGCAATACGCCCTATTAGGAGAATT ACACATATCTCAGGTACTTTAGAAGATGAAGATGAAGATGAAGATAATGATGACATTGTCATGCTAGAG AAAAAAATACGAACATCTAGTATGCCAGAGCAGGCCCATAAAGTCTGTGTCAAAGAGATAAAGAGACTC AAAAAAATGCCTCAGTCAATGCCAGAATATGCTCTGACTAGAAATTATTTGGAACTTATGGTAGAACTT CCTTGGAACAAAAGTACAACTGACCGCCTGGACATTAGGGCAGCCCGGATTCTTCTGGATAATGACCAT TACGCCATGGAAAAATTGAAGAAAAGAGTACTGGAATACTTGGCTGTCAGACAGCTCAAAAATAACCTG AAGGGCCCAATCCTATGCTTTGTTGGCCCTCCTGGAGTTGGTAAAACAAGTGTGGGAAGATCAGTGGCC AAGACTCTAGGTCGAGAGTTCCACAGGATTGCACTTGGAGGAGTATGTGATCAGTCTGACATTCGAGGA CACAGGCGCACCTATGTTGGCAGCATGCCTGGTCGCATCATCAACGGCTTGAAGACTGTGGGAGTGAAC AACCCAGTGTTCCTATTAGATGAGGTTGACAAACTGGGAAAAAGTCTACAGGGTGATCCAGCAGCAGCT CTGCTTGAGGTGTTGGATCCTGAACAAAACCATAACTTCACAGATCATTATCTAAATGTGGCCTTTGAC CTTTCTCAAGTTCTTTTTATAGCTACTGCCAACACCACTGCTACCATTCCAGCTGCCTTGTTGGACAGA ATGGAGATCATTCAGGTTCCAGGTTATACACAGGAGGAGAAGATAGAGATTGCCCATAGGCACTTGATC CCCAAGCAGCTGGAACAACATGGGCTGACTCCACAGCAGATTCAGATACCCCAGGTCACCACTCTTGAC ATCATCACCAGGTATACCAGAGAGGCAGGGGTTCGTTCTCTGGATAGAAAACTTGGGGCCATTTGCCGA GCTGTGGCCGTGAAGGTGGCAGAAGGACAGCATAAGGAAGCCAAGTTGGACCGTTCTGATGTGACTGAG AGAGAAGGTTGCAGAGAACACATCTTAGAAGATGAAAAACCTGAATCTATCAGTGACACTACTGACTTG GCTCTACCACCTGAAATGCCGATTTTGATTGATTTCCATGCTCTGAAAGACATCCTTGGGCCCCCGATG TATGAAATGGAGGTATCTCAGCGTTTGAGTCAGCCAGGAGTAGCAATAGGTTTGGCTTGGACTCCCTTA GGTGGAGAAATCATGTTCGTGGAGGCGAGTCGAATGGATGGCGAGGGCCAGTTAACTCTGACCGGCCAG CTCGGGGACGTGATGAAGGAGTCCGCCCACCTCGCTATCAGCTGGCTCCGCAGCAACGCAAAGAAGTAC CAGCTGACCAATGCTTTTGGAAGTTTTGATCTTCTTGACAACACAGACATCCATCTGCACTTCCCAGCT GGAGCTGTCACAAAAGATGGACCATCTGCTGGAGTTACCATAGTAACCTGTCTCGCCTCACTTTTTAGT GGGCGGCTGGTACGTTCAGATGTAGCCATGACTGGAGAAATTACACTGAGAGGTCTTGTTCTTCCAGTG GGTGGAATTAAAGACAAAGTGCTGGCGGCACACAGAGCGGGACTGAAGCAAGTCATTATTCCTCGGAGA AATGAAAAAGACCTTGAGGGAATCCCAGGCAACGTACGACAGGATTTAAGTTTTGTCACAGCAAGCTGC CTGGATGAGGTTCTTAATGCAGCTTTTGATGGTGGCTTTACTGTCAAGACCAGACCTGGTCTGTTAAAT AGCAAACTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239606
Blue=ORF Red=Cloning site Green=Tag(s) MSSVSPIQIPSRLPLLLTHEGVLLPGSTMRTSVDSARNLQLVRSRLLKGTSLQSTILGVIPNTPDPASD AQDLPPLHRIGTAALAVQVVGSNWPKPHYTLLITGLCRFQIVQVLKEKPYPIAEVEQLDRLEEFPNTCK MREELGELSEQFYKYAVQILDAVSLEERFKMTIPLLVRQIEGLKLLQKTRKPKQDDDKRVIAIRPIRRI THISGTLEDEDEDEDNDDIVMLEKKIRTSSMPEQAHKVCVKEIKRLKKMPQSMPEYALTRNYLELMVEL PWNKSTTDRLDIRAARILLDNDHYAMEKLKKRVLEYLAVRQLKNNLKGPILCFVGPPGVGKTSVGRSVA KTLGREFHRIALGGVCDQSDIRGHRRTYVGSMPGRIINGLKTVGVNNPVFLLDEVDKLGKSLQGDPAAA LLEVLDPEQNHNFTDHYLNVAFDLSQVLFIATANTTATIPAALLDRMEIIQVPGYTQEEKIEIAHRHLI PKQLEQHGLTPQQIQIPQVTTLDIITRYTREAGVRSLDRKLGAICRAVAVKVAEGQHKEAKLDRSDVTE REGCREHILEDEKPESISDTTDLALPPEMPILIDFHALKDILGPPMYEMEVSQRLSQPGVAIGLAWTPL GGEIMFVEASRMDGEGQLTLTGQLGDVMKESAHLAISWLRSNAKKYQLTNAFGSFDLLDNTDIHLHFPA GAVTKDGPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPVGGIKDKVLAAHRAGLKQVIIPRR NEKDLEGIPGNVRQDLSFVTASCLDEVLNAAFDGGFTVKTRPGLLNSKL TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001300948 |
| ORF Size | 2424 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001300948.3 |
| RefSeq Size | 4826 bp |
| RefSeq ORF | 2427 bp |
| Locus ID | 83752 |
| UniProt ID | Q86WA8 |
| Protein Families | Druggable Genome, Protease |
| MW | 90.1 kDa |
| Gene Summary | In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017] |
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