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Abr (NM_001105814) Rat Untagged Clone
CAT＃: RN201866
Abr (untagged ORF) - Rat active BCR-related gene (Abr), (10 ug)
CNY 10,930.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN201866 representing NM_001105814
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCCGCTTAGCCACCGGGGCCTGCCGCGCCTCTCTTGGATCGACACCCTCTACAGCAACTTCAGCT ACGGTGCAGAGGACTACGACGCAGAGGGGCATGAGGAGCAGAAGGGGCCCCCCGAGGGCTCGGAGACCAT GCCATACATCGACGAGTCACCCACCATGTCGCCCCAGCTCAGCGCTCGCAGCCAGGGCGGTGGGGAGAGC ATCTCACCCACCCCACCTGAGGGGTTGGCACCTGGGGTGGAGGCAGGGAAGGGCCTGGAGATGAGGAAGC TAGTTCTCTCTGGGTTTCTGGCCAGTGAAGAGATCTACATTAACCAGTTGGAAGCTCTGTTACTGCCCAT GAAGCCCCTGAAGGCCACAGCCACCACCTCCCAGCCTGTGCTCACCATCCAGCAGATCGAGACCATCTTC TACAAGATCCAGGACATCTACGAGATCCACAAGGAGTTCTACGACAACCTCTGCCCCAAGGTGCAGCAGT GGGACAGCCAGGTCACCATGGGCCATCTTTTCCAGAAACTGGCCAGTCAGCTTGGCGTGTACAAAGCATT TGTGGACAACTATAAAGTCGCCCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAG ATCTCTGAGGAACTCAAAGTGAAAGGACCCAAGGACTCTAAGGACAGCCACACATCAGTCACCATGGAAG CTCTGCTGTATAAGCCTATTGACCGAGTCACTCGGAGTACCCTGGTCCTGCACGATCTGTTGAAGCACAC ACCTGTGGACCACCCCGACTACCCACTGCTTCAGGATGCCCTTCGAATCTCCCAGAATTTTCTATCTAGC ATTAATGAGGATATTGATCCTCGCCGGACTGCAGTCACAACCCCCAAGGGGGAGACTCGGCAGCTGGTGA AGGACGGCTTCCTGGTGGAAATGTCTGAGAGCTCCCGGAAGCTGCGGCACGTCTTTCTCTTCACAGATGT TCTACTGTGTGCCAAGCTAAAGAAGACCTCTGCAGGAAAACATCAGCAGTATGACTGTAAGTGGTACATC CCCCTGGCTGACTTAGTGTTCCCATCCCCTGAGGAGTCCGAGGCCAGTCCCCAGGTACACCCCTTCCCAG ACCACGAGCTAGAGGACATGAAAGTGAAGATCTCTGCCCTCAAGAGTGAGATCCAGAAGGAGAAAGCCAA CAAAGGACAGAGCCGAGCCATTGAGCGCCTCAAAAAGAAGATGTTTGAGAATGAGTTCTTACTGCTGCTC AATTCCCCAACGATCCCATTCCGGATACACAATCGGAATGGAAAGAGTTACCTGTTTCTTCTGTCTTCTG ACTATGAGAGGTCGGAGTGGAGAGAAGCGATTCAGAAACTACAGAAGAAGGATCTCCAGGCCTTTGTCCT GAGCTCTGTGGAGCTCCAGGTGCTCACGGGATCCTGTTTCAAGCTTAGGACTGTGCACAACATTCCTGTC ACCAGCAATAAAGATGACGATGAGTCTCCAGGACTGTACGGCTTCCTTCATGTCATCGTCCACTCTGCCA AGGGCTTTAAACAATCAGCCAATCTTTACTGTACTCTGGAGGTGGATTCCTTTGGCTATTTTGTCAGCAA AGCCAAAACCAGGGTGTTTCGGGACACGACAGAGCCCAAGTGGGATGAGGAGTTTGAGATTGAGCTGGAG GGCTCCCAGTCCCTGAGGATCCTGTGCTATGAGAAATGCTATGACAAGACCAAGGTCAACAAGGACAACA ATGAGATTGTGGACAAGATCATGGGCAAGGGGCAGATCCAGCTGGATCCACAGACAGTAGAAAGCAAGAA CTGGCATACGGATGTGATTGAAATGAATGGGATCAAAGTGGAATTCTCCATGAAATTTACCAGCCGTGAC ATGAGCCTGAAGAGGACTCCATCCAAAAAGCAGACAGGTGTCTTCGGAGTGAAGATCAGTGTGGTGACCA AGCGGGAGCGCTCCAAGGTGCCCTACATAGTCCGGCAGTGCATAGAAGAGGTGGAGAAGAGGGGCATCGA GGAGGTTGGCATCTACAGGATATCAGGGGTGGCCACGGACATCCAGGCCCTGAAGGCTGTCTTTGATGCC AATAACAAGGATATCCTACTGATGCTGAGTGACATGGACATCAACGCTATTGCTGGTACCCTCAAGCTCT ACTTTCGGGAGCTGCCTGAGCCCCTCCTTACAGACCGACTCTACCCAGCCTTCATGGAGGGCATTGCCCT GTCAGATCCTGCTGCCAAGGAGAACTGCATGATGCACCTACTCCGTTCCCTGCCCGACCCCAACCTCATC ACCTTCCTTTTCCTGCTGGAACACTTGAAAAGGGTTGCCGAGAAGGAGCCCATCAACAAGATGTCACTTC ACAACCTTGCCACAGTGTTTGGCCCCACGTTACTGAGACCCTCAGAAGTGGAGAGCAAAGCACATCTCAC ATCAGCTGCAGACATCTGGTCCCATGATGTCATGGCCCAGGTCCAGGTCCTACTCTACTACCTGCAGCAT CCCCCCATTTCCTTCGCAGAACTGAAGCGGAACACACTGTACTTCTCCACAGACGTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001105814 |
| Insert Size | 2580 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001105814.2, NP_001099284.1 |
| RefSeq Size | 4964 bp |
| RefSeq ORF | 2580 bp |
| Locus ID | 287537 |
| UniProt ID | A0A0G2JTR4 |
| Gene Summary | Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (By similarity). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR201866 | Abr (Myc-DDK-tagged ORF) - Rat active BCR-related gene (Abr), (10 ug) |
CNY 10,930.00 |
|
| RR201866L3 | Lenti ORF clone of Abr (Myc-DDK-tagged ORF) - Rat active BCR-related gene (Abr), (10 ug) |
CNY 12,830.00 |
|
| RR201866L4 | Lenti ORF clone of Abr (mGFP-tagged ORF) - Rat active BCR-related gene (Abr), (10 ug) |
CNY 13,970.00 |
