United States
Germany
Japan
United Kingdom
China
Sppl2b (NM_001014200) Rat Untagged Clone
CAT＃: RN203112
Sppl2b (untagged ORF) - Rat signal peptide peptidase-like 2B (Sppl2b), (10 ug)
CNY 7,320.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | RGD1308556 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN203112 representing NM_001014200
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCGGCGCGGCTGGCCGCATCCCTGCTGCTACTCGCGGCCCAGGTGGCCTGTGAGTTCGGTGTAC TGCGAGTTGTGCCCCAAAGCGGTGGGACCCGGGGCAGGGACTACTGCATCCTTTACAACCCACAGTGGGC CCACTTGCCTCATGACCTCAACAAAGTGTCTCTTCTGAAGCTTCGAGACTTGAGCACGACTCAGCTCTGT TCCCACCTCGATGTTCCTGTAGAAGACTTCACCAACCAGATCGCACTGGTGGCTCGGGGCAACTGTACCT TCTATGAGAAAGTGCGGCTGGCCCAGGGCAGTGGGGCACATGGGCTGCTGATAGTCAGCAAGGAGAGACT GGTCCCTCCAAGAGGCAACAAGACACAGTATGAGGAGATAAGCATCCCTGTGGCCCTGCTAAGCCACAGG GACCTTCAAGACATCTTCAGGCGCTTTGGCCACGAGGTAATGGTAGCCCTGTATGCTCCGAGCGAGCCAG TGATGGACTACAACATGGTCATCATCTTCATCATGGCCGTGGGCACCGTCGCCCTTGGTGGCTACTGGGC TGGCAGTCATGATGTGAAGAAGTACATGAAGCATAAGCGAGACGACGTCCCTGAGAAGCAGGAGGATGAG GCGGTGGACGTGACGCCGGTCATGATCTGCGTGTTTGTTGTCATGTGCTGCTTCATGCTTGTGCTCCTCT ACTACTTCTATGACCGCTTGGTCTACGTGATCATTGGGATCTTCTGCCTGGCCTCCTCTACCGGCCTCTA CAGCTGCCTGGCACCCTGTGTGCGCAAGCTGCCCTTCTGCACGTGCAGGGTCCCCGACAACAACCTGCCG TACTTCCACAAGCGTCCACAGGCCCGCATGCTGCTGCTGGCCCTCTTCTGTGTCACTGTCTCCGTGGTGT GGGGTGTCTTCCGTAATGAGGACCAGTGGGCATGGGTCCTGCAGGACACCCTGGGCATTGCCTTCTGCCT GTACATGCTGAGGACCATTCGCCTGCCCACCTTCAAGGCCTGCACACTGCTGCTGCTGGTGCTCTTCGTC TACGACATCTTCTTCGTCTTCATCACCCCCTACCTGACCAAGAGCGGCAACAGCATCATGGTGGAGGTGG CCACTGGGCCCTCGAACTCATCCACCCATGAGAAGCTGCCCATGGTGCTGAAGGTGCCCAGGCTGAACAC CTCGCCTCTCTCCCTGTGTGACCGGCCCTTCTCCCTTCTGGGCTTTGGAGACATCTTGGTGCCAGGGCTG CTGGTGGCCTACTGCCACAGGTTTGATATCCAGGTGCAGTCCTCCAGGATTTACTTTGTGGCCTGCACCA TTGCCTATGGCCTGGGCCTCCTGGTGACCTTCGTGGCTCTCGTCCTCATGCGACATGGCCAGCCTGCACT CCTCTACTTGGTCCCCTGCACACTGCTGACCAGCTGCACCGTGGCTCTGTGGCGCCGGGAGATGGGCGCC TTCTGGACGGGCAGCGGTTTTGCGGATGCACCTCAGACCCCGTGGGCTGCACCCCAGGGACCTGTGCCTC CGAAGGATGTGGATGCCTCTCTCTCGGAGCAGCCTCGGGGTGAAGAGCTGGCCCAGAGCCCCCTGGCCAC TGAGGAGGCAGGAGCCACAGACCCTGCCAAGGATCCTGACAGCCCTGTGGCCGGTCCCCTCAGCCCCTCA AATGGGGACCAAGTCCAGCCTATACCTGTGGTGACCCCAGGGACCTCGGCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001014200 |
| Insert Size | 1734 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001014200.1, NP_001014222.1 |
| RefSeq Size | 2887 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 362828 |
| UniProt ID | Q5PQL3 |
| Gene Summary | Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR203112 | Sppl2b (Myc-DDK-tagged ORF) - Rat signal peptide peptidase-like 2B (Sppl2b), (10 ug) |
CNY 7,320.00 |
|
| RR203112L3 | Lenti ORF clone of Sppl2b (Myc-DDK-tagged ORF) - Rat signal peptide peptidase-like 2B (Sppl2b), (10 ug) |
CNY 9,310.00 |
|
| RR203112L4 | Lenti ORF clone of Sppl2b (mGFP-tagged ORF) - Rat signal peptide peptidase-like 2B (Sppl2b), (10 ug) |
CNY 10,170.00 |
