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Mavs (NM_001005556) Rat Untagged Clone
CAT＃: RN205124
Mavs (untagged ORF) - Rat virus-induced signaling adapter (Visa), nuclear gene encoding mitochondrial protein, (10 ug)
CNY 6,560.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Visa |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN205124 representing NM_001005556
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACATTTGCTGAGGAAAAGACCTATAAGTATATCCGCTACAACCACAGCAAGTTTTGCTGTGTTGATG TTCTGGAGATCCTGCCTTACCTGTCCTGCCTCACAACCAGTGACCAGGATCGATTACGGGCTTCCTACAA GCAACTAGGAAACCAGGGCACACTCTGGGAACTCTTCAATACGCTCCAGCGTCGGCCTGGCTGGGTAGAG GTCTTCATCCGGGCACTGAGGATCTGTGAGCTGCCTGGGCTGGCTGAGCAAGTGACTCGAGTTTATCAGA GCTACCTGCCTCCTGGGGCCTCACTCCACTCCCTAGACCCATTGCAGTCACCAAGAATTCCTACCACGGT TTCCGAACCTTCTGCATTTGCAGCAGGCCACACCATCCCTGACAGTGGCTTCCAAGATAAACCAGGTTAC CCTAAGCCTGTCCAGGACACCCAGCCACCAAAGTCCCCAGTAGAGAATTCGGAGGAACCCCCACAGGCCA ACTTTGGGGCCATTCCAAGGATGTCGGGTGACTCTTTGATATCCTCACCTAACCCACCGGCCCTCAGCCC TCAGCCCTCCAGAGAGCATCCCGAGCAAGAACCCGAACTGGGGGGCCCCTCCACAGCAAATGTTGACTCT GTTCCCATAGCAACCTATGGACCTGTGTCTCCAACTGTTTCCTTCCAGCCCCTTCCACGTATTGCCCCGA GGACAAACCTCTCGCCTGGGGTCACAGTATCAGCTCTATCTGCCAAGACCACTTTGTCCTCCTCTTCTAC TGGATCAGCTTTTGCAAAGGGAGCAGGTGACCAGGCCAAGGCTGCCACCTGTGTCAGCACTAAAGAGGGA GTACCTACCAATTCTGTGACTACCAGCTCAGTGCCTTCCATCAAACCAGTACCAGTAAATACCATGTCTT CCAAGTTGCCCATCAGTACAAAGTCCACTGCTGCAACGCCCTCTACTGTGCCCACTAATATAGCGCCATC AAAATTACCCATCAACTCAGTATATACTGGCATAGTGCCATCCAAAGTGACTGCTAGTGTGGCCAAAGCA AGTGCCAGCACAATGCCACCTGAGAGGAACAACAAGCAAGCCAAGGAGACCCTGGAGGCTCCAGCAACCG TAGTCACCACTGGAAGCAGCCTGACCAGACCAGATATCAGTTCCAGGAGCTTGCACTCTGGGCCAGAGTT AAGCAAGCCAGGGGTGCTGGTGTCCCAGGTGGACAACGAGCCATTCTCAGCCTGCTCTATGGACCTTGCC ATCAGCCCTAGCACCTCCTTGGGCTCAGAACCCAACCATGGTCCAGAGGAGAATGAGTATTCATCCTTTC GAATCCAGGTGGATAAAAGTCCCAGTGTTGATCTGTTAGGAAGCCCTGAGCCACTAGCCACCCAGCAGTC CCCAGAAGAGGAAGAGCCTTGTGCCAGTTCAGTGTCCTGGGCTAAGTGGCTGGGGGCCACCAGTGCACTC TTGGCTGCATTCCTGGCAGTGATGCTCTACCGTAGCAGGCACCTGGCCCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001005556 |
| Insert Size | 1524 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001005556.1, NP_001005556.1 |
| RefSeq Size | 2965 bp |
| RefSeq ORF | 1524 bp |
| Locus ID | 311430 |
| UniProt ID | Q66HG9 |
| Gene Summary | Required for innate immune defense against viruses. Acts downstream of DHX33, DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR205124 | Mavs (Myc-DDK-tagged ORF) - Rat virus-induced signaling adapter (Visa), nuclear gene encoding mitochondrial protein, (10 ug) |
CNY 6,560.00 |
|
| RR205124L3 | Lenti ORF clone of Mavs (Myc-DDK-tagged ORF) - Rat virus-induced signaling adapter (Visa), nuclear gene encoding mitochondrial protein, (10 ug) |
CNY 8,460.00 |
|
| RR205124L4 | Lenti ORF clone of Mavs (mGFP-tagged ORF) - Rat virus-induced signaling adapter (Visa), nuclear gene encoding mitochondrial protein, (10 ug) |
CNY 9,220.00 |
