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Krt17 (NM_212545) Rat Untagged Clone
CAT＃: RN205536
Krt17 (untagged ORF) - Rat keratin 17 (Krt17), (10 ug)
CNY 5,610.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Ka17 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN205536 representing NM_212545
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTACCACCATCCGCCAGTTCACGTCCTCCAGCTCCATCAAGGGCTCCTCTGGCCTGGGTGGCGGCT CATCTAGGACCTCCTGCCGACTGTCTGGCAGCCTGGGTGCAGGCTCCTGCAGGCTGGGGTCAGCTAGTGG CCTGGGCAGTGCTCTTGGGGGCAACAGTTACTCCAGCTGCTACAGCTTTGGTACTGGCAGTGGTTATGGA GGCAACTTTGGGGGTGTTGATGGGCTGCTGGCTGGAGGGGAGAAGGCCACCATGCAGAACCTCAACGACC GCCTGGCCTCCTACCTGGACAAGGTGCGTGCCCTGGAAGAGGCCAACACCGAGCTGGAGGTGAAGATCCG AGACTGGTACCAGAAGCAGGCCCCAGGGCCAGCCCGCGACTACAGTGCTTATTACCAGACCATTGAGGAT CTGAAGAACAAGATCCTCGTGGCCACTGTGGATAATGCCAGCATCCTACTCCAGATTGACAATGCCCGCT TGGCAGCTGATGACTTCCGTACCAAGTTTGAGACGGAGCAGGCCCTGCGCATGAGTGTGGAGGCGGACAT CAATGGCCTACGCCGGGTGCTGGATGAGCTGACCCTGGCCAGAGCTGACCTGGAGATGCAGATTGAGAAT CTCAAGGAGGAGCTGGCCTACCTGAAGAAGAACCATGAGGAGGAGATGAATGCTCTGAGAGGCCAGGTGG GCGGCGAAATCAACGTGGAGATGGACGCAGCCCCTGGTGTGGACCTGAGCCGCATCCTGTCAGAGATGCG GGATCAGTACGAGAAGATGGCTGAGAAGAACCGCAAGGATGCCGAAGATTGGTTCTTCAGCAAGACTGAG GAGCTAAACCGCGAGGTGGCCACCAACAGCGAGCTGGTGCAGAGCGGCAAGAGCGAGATCTCTGAGCTCC GGCGCACCATGCAGGCCCTGGAGATCGAGCTGCAGTCCCAGCTCAGCATGAAAGCATCCCTGGAGGGCAG CCTGGCAGAGACAGAGAACCGCTACTGCGTGCAGCTGTCCCAGATCCAGGGTTTGATTGGCAGCGTGGAG GAGCAGCTGGCTCAGCTGCGCTGCGAGATGGAGCAGCAGAATCAGGAGTACAAGATCCTGCTGGATGTGA AGACTCGGCTGGAGCAGGAGATCGCCACCTACCGCCGTCTGCTGGAGGGCGAGGATGCCCACCTGACTCA GTACAAGCCAAAAGAACCTGTGACCACCCGCCAGGTGCGCACCATTGTGGAAGAGGTCCAGGATGGCAAG GTCATCTCATCCCGGGAGCAGGTCCACCAGACCACCCGCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_212545 |
| Insert Size | 1302 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_212545.2, NP_997710.1 |
| RefSeq Size | 1536 bp |
| RefSeq ORF | 1302 bp |
| Locus ID | 287702 |
| UniProt ID | Q6IFU8 |
| Gene Summary | Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR205536 | Krt17 (Myc-DDK-tagged ORF) - Rat keratin 17 (Krt17), (10 ug) |
CNY 5,610.00 |
|
| RR205536L3 | Lenti ORF clone of Krt17 (Myc-DDK-tagged ORF) - Rat keratin 17 (Krt17), (10 ug) |
CNY 7,510.00 |
|
| RR205536L4 | Lenti ORF clone of Krt17 (mGFP-tagged ORF) - Rat keratin 17 (Krt17), (10 ug) |
CNY 8,270.00 |
