Nabp2 (NM_001244819) Rat Untagged Clone

Specifications

Product Data
Type	Rat Untagged Clone
Tag	Tag Free
Synonyms	Obfc2b; RGD1308158
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >RN216054 representing NM_001244819 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACGACCGAGACCTTCGTGAAGGATATCAAGCCCGGGCTCAAGAATCTGAACCTTATCTTCATTGTAC TGGAGACAGGTCGGGTGACCAAGACAAAGGATGGGCACGAGGTTCGGACTTGTAAAGTGGCAGACAAAAC GGGCAGCATCAACATCTCAGTGTGGGACGATGTGGGCAACCTAATCCAACCCGGGGACATTATCCGACTC ACCAAAGGGTACGCCTCAGTGTTCAAAGGTTGTCTGACACTATACACTGGCCGTGGGGGCGATCTGCAAA AGATTGGAGAATTCTGCATGGTTTATTCTGAAGTTCCTAATTTCAGCGAGCCCAATCCAGAGTATAACAC CCAGCAGGCATCCAACAAATCGGTGCAGAATGACAGCAGCCCTACTGCCCCACAAGCTACCACAGGACCC CCTGCCGCCTCTCCAGCTTCCGAGAGCCAGAACGGGAATGGACTGAGCACCCAGCCAGGTCCTGTTGGTG GCCCCCATCCCTCTCACGCCCCCTCACATCCCCCCAGCACCCGAATCACTCGAAGCCAGCCCAACCACAC GCCTTCTGGCCCTCCTGGCCCCTCCAGCAGCCCTGTCAGCAACGGCAAAGAAACCCGCAGGAGCAGCAAG AGATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001244819
Insert Size	636 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001244819.1, NP_001231748.1
RefSeq Size	1111 bp
RefSeq ORF	636 bp
Locus ID	362813
UniProt ID	Q3SWT1
Gene Summary	Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) contains different sequence for its 5' end, which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.

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