Fkbp4 (NM_001191863) Rat Untagged Clone

Specifications

Product Data
Type	Rat Untagged Clone
Tag	Tag Free
Synonyms	FKBP-4; FKBP-52; p59
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >RN216713 representing NM_001191863 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCGCCGAGGAGATGAAGGTGGCGGAGAACGGGGCGCAATCGGCGCCCCTGCCTCTCGAAGGAGTGG ACATCAGCCCCAAGCAGGACGAGGGCGTGCTCAAGGTCATCAAGAGAGAGGGTACAGGCACAGAGACAGC CATGATTGGGGACCGAGTCTTTGTCCACTACACTGGCTGGCTGCTAGATGGCACAAAGTTTGACTCCAGT TTGGACCGCAAGGACAAATTCTCCTTTGACCTGGGAAAAGGGGAGGTCATCAAGGCTTGGGATATTGCTG TGGCAACCATGAAAGTGGGGGAAGTGTGCCACATCACCTGCAAGCCAGAATACGCCTACGGTTCAGCAGG CAGCCCTCCAAAGATTCCCCCAAATGCCACACTTGTATTTGAGGTGGAGCTGTTTGAGTTCAAAGGAGAA GATCTTACAGAAGATGAAGATGGTGGGATCATCCGCAGAATACGGACTCGGGGGGAAGGCTATGCCAGGC CCAATGATGGCGCTATGGTAGAAGTGGCACTAGAAGGCTACTATAATGACCGGCTGTTTGACCAGCGGGA GCTCTGCTTTGAAGTCGGGGAAGGGGAAAGCCTGGATCTGCCCTGTGGGCTGGAGGAGGCCATTCAGCGC ATGGAGAAAGGAGAACATTCCATTGTGTACCTCAAACCTAGCTATGCTTTTGGCAGTGTTGGGAAGGAAA GGTTCCAGATCCCACCACATGCTGAGCTGAGGTATGAAGTACATCTGAAGAGTTTTGAGAAGGCCAAGGC ATCTTGGGAGATGAACTCTGAGGAGAAGCTGGAGCAGAGCAACATAGTGAAAGAAAGGGGCACCGTGTAC TTCAAGGAAGGCAAGTACAAGCAAGCCTTACTGCAGTACAAGAAGATTGTGTCTTGGCTAGAATACGAGT CTAGTTTTTCCGGTGAGGAAATGCAAAAGGTCCATGCGCTCCGACTGGCCTCACATCTCAATCTGGCCAT GTGTCACCTGAAACTGCAGGCCTTCTCAGCTGCCATCGAAAGCTGTAACAAGGCCTTGGAGCTGGACAGC AACAATGAGAAGGGCCTGTTTCGCCGGGGAGAGGCACACCTGGCCGTGAATGACTTTGACCTGGCACGAG CTGACTTCCAAAAGGTCCTGCAGCTCTATCCCAGCAACAAAGCCGCCAAGACCCAGCTGGCTGTGTGCCA GCAGCGGACCCGCAGGCAGCTTGCCCGGGAAAAGAAGCTCTATGCCAACATGTTTGAGAGGCTGGCTGAG GAGGAACATAAGGCCAAGACAGAAGTGGCTGCAGGAGACCATCCCACTGATGCTGAGATGAAGGGTGAGC CGAACAATGTGGCAGGCAACCAGGCTCAGGTGAAGACAGAAGCATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001191863
Insert Size	1377 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001191863.1, NP_001178792.1
RefSeq Size	2845 bp
RefSeq ORF	1377 bp
Locus ID	260321
UniProt ID	Q9QVC8
Gene Summary	Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. May have a protective role against oxidative stress in mitochondria (By similarity). Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. The PPIase activity controls neuronal growth cones via regulation of TRPC1 channel opening.[UniProtKB/Swiss-Prot Function]

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