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IL33 (NM_033439) Human Untagged Clone
CAT＃: SC100114
IL33 (untagged)-Human interleukin 33 (IL33), transcript variant 1
CNY 3,600.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC100114 sequence for NM_033439 edited (data generated by NextGen Sequencing)
ATGAAGCCTAAAATGAAGTATTCAACCAACAAAATTTCCACAGCAAAGTGGAAGAACACA GCAAGCAAAGCCTTGTGTTTCAAGCTGGGAAAATCCCAACAGAAGGCCAAAGAAGTTTGC CCCATGTACTTTATGAAGCTCCGCTCTGGCCTTATGATAAAAAAGGAGGCCTGTTACTTT AGGAGAGAAACCACCAAAAGGCCTTCACTGAAAACAGGTAGAAAGCACAAAAGACATCTG GTACTCGCTGCCTGTCAACAGCAGTCTACTGTGGAGTGCTTTGCCTTTGGTATATCAGGG GTCCAGAAATATACTAGAGCACTTCATGATTCAAGTATCACAGGAATTTCACCTATTACA GAGTATCTTGCTTCTCTAAGCACATACAATGATCAATCCATTACTTTTGCTTTGGAGGAT GAAAGTTATGAGATATATGTTGAAGACTTGAAAAAAGATGAAAAGAAAGATAAGGTGTTA CTGAGTTACTATGAGTCTCAACACCCCTCAAATGAATCAGGTGACGGTGTTGATGGTAAG ATGTTAATGGTAACCCTGAGTCCTACAAAAGACTTCTGGTTGCATGCCAACAACAAGGAA CACTCTGTGGAGCTCCATAAGTGTGAAAAACCACTGCCAGACCAGGCCTTCTTTGTCCTT CATAATATGCACTCCAACTGTGTTTCATTTGAATGCAAGACTGATCCTGGAGTGTTTATA GGTGTAAAGGATAATCATCTTGCTCTGATTAAAGTAGACTCTTCTGAGAATTTGTGTACT GAAAATATCTTGTTTAAGCTCTCTGAAACTTAG Clone variation with respect to NM_033439.3 >OriGene 5' read for NM_033439 unedited
TATTTTGTAATACGACTCACTATAGGGNCGCGCCGCGCAATTCGGCACGAGGGCACGAGG CAGGGAAGAAATCAAACAGACACAAGATACTGAAAATGAAGCCTAAAATGAAGTATTCAA CCAACAAAATTTCCACAGTCAAAGTGGCAAGAACACAGCAAGCAAAGCCTTGTGTTTCAA GCTGGGCAAAATCCCAACAGAAGGCCAAAGAAGTTTGCCCCATGTACTTTATGAAGCTCC GCTCTGGCCTTATGATAAAAAAGGAGGCCTGTTACTTTAGGAGAGAAACCACCAAAAGGC CTTCGCTGAAAACAGGTACAAAGCACAAAAGACATCTGGTACTCGCTGCCTGTCAACAGC AGTCTACTGTGGAGTGCTTTGCCTTTGGTATATCAGGGGTCCAGAAATATACTAGAGCAC TTCATGATTCAAGTATCACAGGAATTTCACCTATTACAGAGCATCTTGCTTCTCTAAGCA CATACAATGATCAATCCATTACTTTTGCTTTGGAGGATGAAAGTTATGAGATATATGTTG AAGACTTGAAAAAAGATGAAAAGAAAGATAAGGCGCCACTGAGCTACTATGAGTCTCAAC ACCCCCTCAAATGAAATAGGTGACGGTGTTGATGGTAAGATAGTAATGGTAACCCTTGAG TCCTACAACAGACCTCTGGTTGCATGCCAACAACAAGGAAACACTCTGTGGGAGCTTCCT AAGTTGTGAAAACACCACTGTCCACACACAGCCCTTCTTTGTACCTTTATAATATGCACC TCCAACTGTGTTTCATTTGCATGCACGACTGATCCCTGCACGGTCCAAAGGTGTAAAGGA TTATCACTCTTGCTCCGCACCAAAGCACACCCTTCTTGAGAACTCGGGGCCCAGAAAAAA CCTTGTTTGAACCCCTCTTGAACTAACTGCGAGGACACCTGGGAGTCTTGGGTTGAGTAC CCAATGCTCCCCCTCGGAAAGACATCAAGAATAC >OriGene 3' read for NM_033439 unedited
TTAGCTTTGNACCGCGGCCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGGAAAA TATACTTTATTCAATAATATAAACAATGTAGATATATTTGATTATTTAATAATCATTTTA AGTTTATTGCACAGATGCACATGTCAATAATTAGTGTTTTTCAGATGGGATGATATACAT TCTGCTTTTATTTTTATCTCTTTGGTAACAATTATTGACAGAACAATGAAACAAAGATAA ATTGTTTTACAGTTGTAATACCCTTGTATGGTAATTCTCAGCCTCTTTTATCTTATATTC TACTAGCACTTACATCTAATAGGTCTCAATAAAGTAGAAATGTAAAAGTATGTATTTTCA GAAAAGGTCATATTTCATAAAGATTCTGTTACTATGTTAGTCATTTATCATAAGTGTTAA GTCTAAGAAAAGTTGTAATAGAAATTGCTAAGACTTTAAAATAAAAACTACTCCTTTAGT AGTTAAAAAATGTTATTATATGGTTGAGTATAAATTTTATTGCCCTAGTGACAGTAAAAA ACAAAAACGTTTAGCAAAAAAATATTGCCATTAATAGCTTTATCTAAAATTCTACAACAG ACAAAGCAGAATAAACGTTTTGGCATCCAGAGGTCAGGTGATACAGAAATGAAGTTCAGC AGGTGCAAAAGATATATCAAGGGCATGGTAGTTAAAAGAAATGAAAAGAGACAGATGTCA AATGAATATTCCACAGTAAGCAGTGTTATCAGGAAGCTGGAATACAAAAAGACTTGTGCA CATGGAAAAATAAGGATTAGAAAGCACTTTTGCCCAATGTNGACAGTGAGTATTTAAAGA CATANGTCCCTGGAAGCCCCGGTCANAAGGNATGGTANGCCATGGACATGAGGNACAGTC CAGTACTGAAANTTTAATGTNATTCCGNGTCTCATCTAGGCTCTGGTAGTTAAAAGATTN CTGCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033439 |
| Insert Size | 2630 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033439.2, NP_254274.1 |
| RefSeq Size | 2644 bp |
| RefSeq ORF | 813 bp |
| Locus ID | 90865 |
| UniProt ID | O95760 |
| Protein Families | Secreted Protein |
| Protein Pathways | Cytosolic DNA-sensing pathway |
| Gene Summary | The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as 1). Variants 1, 4, and 5 all encode the same isoform (a). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
,De Boeck, A;Ahn, BY;D'Mello, C;Lun, X;Menon, SV;Alshehri, MM;Szulzewsky, F;Shen, Y;Khan, L;Dang, NH;Reichardt, E;Goring, KA;King, J;Grisdale, CJ;Grinshtein, N;Hambardzumyan, D;Reilly, KM;Blough, MD;Cairncross, JG;Yong, VW;Marra, MA;Jones, SJM;Kaplan, DR;McCoy, KD;Holland, EC;Bose, P;Chan, JA;Robbins, SM;Senger, DL;,
Nat Commun
,PubMed ID 33020472
[IL33]
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A functional DC cross talk promotes human ILC homeostasis in humanized mice
,Lopez-Lastra, S;Masse-Ranson, G;Fiquet, O;Darche, S;Serafini, N;Li, Y;Dusséaux, M;Strick-Marchand, H;Santo, JP;,
Blood Advances
[IL33]
|
|
IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis
,Zhang, Y;Davis, C;Shah, S;Hughes, D;Ryan, JC;Altomare, D;Peña, MM;,
Mol. Carcinog.
,PubMed ID 27120577
[IL33]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207989 | IL33 (Myc-DDK-tagged)-Human interleukin 33 (IL33), transcript variant 1 |
CNY 3,600.00 |
|
| RC207989L1 | Lenti ORF clone of Human interleukin 33 (IL33), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC207989L2 | Lenti ORF clone of Human interleukin 33 (IL33), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC207989L3 | Lenti ORF clone of Human interleukin 33 (IL33), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC207989L4 | Lenti ORF clone of Human interleukin 33 (IL33), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG207989 | IL33 (tGFP-tagged) - Human interleukin 33 (IL33), transcript variant 1 |
CNY 5,200.00 |
