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Inosine triphosphate pyrophosphatase (ITPA) (NM_033453) Human Untagged Clone
CAT＃: SC100225
ITPA (untagged)-Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C20orf37; DEE35; dJ794I6.3; HLC14-06-P; ITPase; My049; NTPase |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC100225 sequence for NM_033453 edited (data generated by NextGen Sequencing)
ATGGCGGCCTCATTGGTGGGGAAGAAGATCGTGTTTGTAACGGGGAACGCCAAGAAGCTG GAGGAGGTCGTTCAGATTCTAGGAGATAAGTTTCCATGCACTTTGGTGGCACAGAAAATT GACCTGCCGGAGTACCAGGGGGAGCCGGATGAGATTTCCATACAGAAATGTCAGGAGGCA GTTCGCCAGGTACAGGGGCCCGTGCTGGTTGAGGACACTTGTCTGTGCTTCAATGCCCTT GGAGGGCTCCCCGGCCCCTACATAAAGTGGTTTCTGGAGAAGTTAAAGCCTGAAGGTCTC CACCAGCTCCTGGCCGGGTTCGAGGACAAGTCAGCCTATGCGCTCTGCACGTTTGCACTC AGCACCGGGGACCCAAGCCAGCCCGTGCGCCTGTTCAGGGGCCGGACCTCGGGCCGGATC GTGGCACCCAGAGGCTGCCAGGACTTTGGCTGGGACCCCTGCTTTCAGCCTGATGGATAT GAGCAGACGTACGCAGAGATGCCTAAGGCGGAGAAGAACGCTGTCTCCCATCGCTTCCGG GCCCTGCTGGAGCTGCAGGAGTACTTTGGCAGTTTGGCAGCTTGA Clone variation with respect to NM_033453.2 >OriGene 5' read for NM_033453 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTTTTCGGTGGCTCAG CTGGGTAACCGGGGATCACCATGGCGGCCTCATTGGTGGGGAAGAAGATCGTGTTTGTAA CGGGGAACGCCAAGAAGCTGGAGGAGGTCGTTCAGATTCTAGGAGATAAGTTTCCATGCA CTTTGGTGGCACAGAAAATTGACCTGCCGGAGTACCAGGGGGAGCCGGATGAGATTTCCA TACAGAAATGTCAGGAGGCAGTTCGCCAGGTACAGGGGCCCGTGCTGGTTGAGGACACTT GTCTGTGCTTCAATGCCCTTGGAGGGCTCCCCGGCCCCTACATAAAGTGGTTTCTGGAGA AGTTAAAGCCTGAAGGTCTCCACCAGCTCCTGGCCGGGTTCGAGGACAAGTCAGCCTATG CGCTCTGCACGTTTGCACTCAGCACCGGGGACCCAAGCCAGCCCGTGCGCCTGTTCAGGG GCCGGACCTCGGGCCGGATCGTGGCACCCAGAGGCTGCCAGGACTTTGGCTGGGACCCCT GCTTTCAGCCTGATGGATATGAGCAGACGTACGCAGAGATGCCTAAGGCGGAGAAGAACG CTGTCTCCCATCGCTTCCGGGCCCTGCTGGAGCTGCAAGAGTACTTTGGCAGTTTGGCAG CTTGACTTCTGCAGCTGGAGGAGGCNNCCTCAGCCCGNNGATCTGGGAGGGCTACCCCAA ACCTCCCGCATCGGGCAGGCACCCCCCTGAGTACTTCCTTCAGGGTTCCCCTTGTGAGGT GTCGAGTACCTCACCGCCCTTCTGGAGGACACCTGGTCTGCTCTGAAAACTCTGCGAGTG CACCCCTCTCTGCCCTTAGATCACTGTTTCTCTAAACCCCAGCCTGGGTCTGAAAGACCT TGGGGGAAACTTACTCGGGG >OriGene 3' read for NM_033453 unedited
CTTGGACGCGGCCGCTATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAAAACAAATATA GCTGGTTTATTTTGGAAACAAGTCTCATCCAAAAATGTTATTTACTGCATTTAAAAACCA TGGAAGGCGATTTGCATGGTTCCTCCCCACGCCCTCACTCCCACCAAGTACAGCTTTACC ACCCAAGGTCCTTTCAGGACCCCAGGCCTGGCGGCTGTAGGAAAGAGCAGTGAATCCTAA GGGCAAGAGAATGGCGTCCACTTGCCAAAGTTTCTCAAAGCAGAGCCAGCTGCTCCTCCA GACAGGCCGGTGAGGCTACTCGACACCCTCACAAAGGGGAAACCCTGAAGGAAGTACTTC AGGGGGTGCCTGCCCGATGCGGGAGGTTTTGGGCTAGCCCTCCCCAGATCCCCGGCCTGA GGGGCCTCCTCCAGCTGCAGAAGTCAAGCTGCCAAACTGCCAAAGTACTCCTGCAGCTCC AGCAGGGCCCGGAAGCGATGGGAGACAGCGTTCTTCTCCGCCTTAGGCATCTCTGCGTAC GTCTGCTCATATCCATCAGGCTGAAAGCAGGGGTCCCAGCCAAAGTCCTGGCAGCCTCTG GGTGCCACGATCCGGCCCGAGGTCCGGCCCCTGAACAGGCGCACGGGCTGGCTTGGGTCC CCGGTGCTGAGTGCAAACGTGCAGAGCGCATAGGCTGACTTGTCCTCGAACCCGGCCAGG AGCTTGTGGAGACCTTCAGGCTTTAACTTCTCCAGAAACCACTTTATGTAGGGGCCGGCG AGCCCTCCAAGGGCATCGAAAGCCAGAAAAGGTGTCCTTAACCACCACCGGCCCCCTGTC CTTGACGAACTGCCTCCTGCCCTTTCTGTACGGAAAATCCACTCGGCTCCCTCTGGTACT CCGGCAGGTCCATTTTCGGTCCACCAAACCGCTCGCAAACTTATTTCGTATACCCGAACG ACCTCCTCCCGCTTTCGCCCTCCCCGCCAATCCCATC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033453 |
| Insert Size | 1070 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033453.2, NP_258412.1 |
| RefSeq Size | 1206 bp |
| RefSeq ORF | 585 bp |
| Locus ID | 3704 |
| UniProt ID | Q9BY32 |
| Domains | Ham1p_like |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
| Gene Summary | This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204021 | ITPA (Myc-DDK-tagged)-Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1 |
CNY 2,400.00 |
|
| RC204021L1 | Lenti ORF clone of Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204021L2 | Lenti ORF clone of Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC204021L3 | Lenti ORF clone of Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204021L4 | Lenti ORF clone of Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG204021 | ITPA (tGFP-tagged) - Human inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1 |
CNY 4,000.00 |
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