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hnRNP K (HNRNPK) (NM_031262) Human Untagged Clone
CAT＃: SC107869
HNRNPK (untagged)-Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 3
CNY 3,656.00
| Cited in 3 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AUKS; CSBP; HNRPK; TUNP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_031262, the custom clone sequence may differ by one or more nucleotides
ATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCAATGGTGAATTTGGTAAACGCCCTG CAGAAGATATGGAAGAGGAACAAGCATTTAAAAGATCTAGAAACACTGATGAGATGGTTGAATTACGCAT TCTGCTTCAGAGCAAGAATGCTGGGGCAGTGATTGGAAAAGGAGGCAAGAATATTAAGGCTCTCCGTACA GACTACAATGCCAGTGTTTCAGTCCCAGACAGCAGTGGCCCCGAGCGCATATTGAGTATCAGTGCTGATA TTGAAACAATTGGAGAAATTCTGAAGAAAATCATCCCTACCTTGGAAGAGGGCCTGCAGTTGCCATCACC CACTGCAACCAGCCAGCTCCCGCTCGAATCTGATGCTGTGGAATGCTTAAATTACCAACACTATAAAGGA AGTGACTTTGACTGCGAGTTGAGGCTGTTGATTCATCAGAGTCTAGCAGGAGGAATTATTGGGGTCAAAG GTGCTAAAATCAAAGAACTTCGAGAGAACACTCAAACCACCATCAAGCTTTTCCAGGAATGCTGTCCTCA TTCCACTGACAGAGTTGTTCTTATTGGAGGAAAACCCGATAGGGTTGTAGAGTGCATAAAGATCATCCTT GATCTTATATCTGAGTCTCCCATCAAAGGACGTGCACAGCCTTATGATCCCAATTTTTACGATGAAACCT ATGATTATGGTGGTTTTACAATGATGTTTGATGACCGTCGCGGACGCCCAGTGGGATTTCCCATGCGGGG AAGAGGTGGTTTTGACAGAATGCCTCCTGGTCGGGGTGGGCGTCCCATGCCTCCATCTAGAAGAGATTAT GATGATATGAGCCCTCGTCGAGGACCACCTCCCCCTCCTCCCGGACGAGGCGGCCGGGGTGGTAGCAGAG CTCGGAATCTTCCTCTTCCTCCACCACCACCACCTAGAGGGGGAGACCTCATGGCCTATGACAGAAGAGG GAGACCTGGAGACCGTTACGACGGCATGGTTGGTTTCAGTGCTGATGAAACTTGGGACTCTGCAATAGAT ACATGGAGCCCATCAGAATGGCAGATGGCTTATGAACCACAGGGTGGCTCCGGATATGATTATTCCTATG CAGGGGGTCGTGGCTCATATGGTGATCTTGGTGGACCTATTATTACTACACAAGTAACTATTCCCAAAGA TTTGGCTGGATCTATTATTGGCAAAGGTGGTCAGCGGATTAAACAAATCCGTCATGAGTCGGGAGCTTCG ATCAAAATTGATGAGCCTTTAGAAGGATCCGAAGATCGGATCATTACCATTACAGGAACACAGGACCAGA TACAGAATGCACAGTATTTGCTGCAGAACAGTGTGAAGCAGTATTCTGGAAAGTTTTTCTAA >OriGene 5' read for NM_031262 unedited
GGAATTTGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGAGGCGGCGCG GCAGCGGAGGGACGGCAGTCTCGCGCGGCTACTGCAGCACTGGGGTGTCAGTTGTTGGTC CGACCCAGAACGCTTCAGTTCTGCTCTGCAAGGATATATAATAACTGATTGGTGTGCCCG TTTAATAAAAGAATATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCA ATGGTGAATTTGGTAAACGCCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAGAT CTAGAAACACTGATGAGATGGTTGAATTACGCATTCTGCTTCAGAGCAAGAATGCTGGGG CAGTGATTGGAAAAGGAGGCAAGAATATTAAGGCTCTCCGTACAGACTACAATGCCAGTG TTTCAGTCCCAGACAGCAGTGGCCCCGAGCGCATATTGAGTATCAGTGCTGATATTGAAA CAATTGGAGAAATTCTGAAGAAAATCATCCCTACCTTGGAAGAGGGCCTGCAGTTGCCAT CACCCACTGCAACCAGCCAGCTCCCGCTCGAATCTGATGCTGTGGAATGCTTAAATTACC AACACTATAAAGGAAGTGACTTTGACTGCGAGTTGAGGCTGTTGATTCATCAGAGTCTAG CAGGAGGAATTATTGNNGGTCAAAGTGCTAAAATCAAAGAACTTCGAGAGAACACTCAAA CCACCATCAAGCTTTTNNCAGAATGCTGTCCTCATTCCCACTGACAGANTGTTCTTATTG GAGGAAAAACCCGATAGGNTGGTANAGTGCATAAAGATCTNCCTTGATCTTATATCTGAG TCTCCATCAAAAGACGTGCACAGCCTTATGATCCCCATTTTTACGATGAACTATGAAATA TGGGG >OriGene 3' read for NM_031262 unedited
GAGTCGAGTTTTTTTTTTTTTTTTTTTAGCATCATGGGTGTTTTATTTATTTGGAAGTGA ATTTTAACTATCAATACAAATGCCAAGATACTACACAAAACATCCACAGGAACTTTTTTC ATCTTTTTTTTTTTTGAATTGTACACAAACATTTCCTACATAATCCAACATACAACAGAG AAATGGTACATCTTTTTCTTTCAATTTGCATACAATGGAAAAACAAGTATATATATATTT TACAAAGTTTAACTAATAAGACACTAGAGCAAATTGACAGTTTAAGTCTATAGGTGAGAA ATTATCTAATAAAAATAATCAATTTTTTCAGCATTAGTCACTTCCATAACCAAGTGTTAT TCTGATTAATAAAACTTGCTGCCAATCAGAATTCTGGTATATACTCATACCATTACTCAA CTTGTAGTACTGCTCCCCACCTTAGTTCTTCACAACTAACATAGAAAATTGTTGAAAAGT AGGGGCAAGCATTTGCAAAAACAAACAAAAAATCCCCAGCTTATTATAAGCATGAATATG TATGATGGAATTTCTTCCCAGCAATAGACTTCCCCAACCATCAGAAATCACCAGAACTAA AGTTGCCAAGTTATTTTGCCTATGTCCAACAAGAGATGCACTTATATGTCCAACAGAGGA GCTGAAAATAAACTTAGTGTTTAGTTGGGGGGTGGGTTGGGAAATNCAGCAACATTTTAA ATGACTGTCTTAAAAAAAAATGACCCCCAAAATAGGTTCACTAAATTTATTTAAAAATCA TAAAACGTTTCTTACAAAGAAGCATACATTTCTGCACACTGCTCTGAACAGATGCAGGAA CATGGGGCCATTTGTACTTTTCCTCCTGTCCCACCCCCAATGTTCAAGTGACCCAAAGCA AGGGGTTAAATAATTACCTGGGGGGGATTTTTTAAACACCACCACTACCGAAAATAAATC CCCTCCTCTGCCGTGTTNAAAATTCAATGTAGTTTTTGCCGCCCTCCCCCCCCACCTGTT GTTAGAACAAACTTCCTTGTGACACCAAGTTTCTCACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_031262 |
| Insert Size | 2840 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_031262.1, NP_112552.1 |
| RefSeq Size | 2770 bp |
| RefSeq ORF | 1392 bp |
| Locus ID | 3190 |
| UniProt ID | P61978 |
| Domains | KH |
| Protein Pathways | Spliceosome |
| Gene Summary | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) uses an alternate acceptor splice site at the last coding exon compared to transcript variant 1. This results in a frame-shift and an isoform (b) with a distinct C-terminus compared to isoform a. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies
,Toki, N;Takahashi, H;Zucchelli, S;Gustincich, S;,
BioRxiv
[HNRNPK]
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Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression
,null,
Oncotarget
,PubMed ID 26317903
[HNRNPK]
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The Importance of Heterogeneous Nuclear Ribonucleoprotein K on Cytochrome P450 2D2 Gene Regulation: Its Binding Is Reduced in Dark Agouti Rats
,Noriaki Sakai, Kentaro Q. Sakamoto, Shoichi Fujita, and Mayumi Ishizuka,
Drug Metab. Dispos., Aug 2009; 37: 1703 - 1710.
[HNRNPK]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204921 | HNRNPK (Myc-DDK-tagged)-Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 3 |
CNY 3,656.00 |
|
| RC204921L3 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204921L4 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG204921 | HNRNPK (tGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 3 |
CNY 4,370.00 |
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