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ELOVL4 (NM_022726) Human Untagged Clone
CAT＃: SC108083
ELOVL4 (untagged)-Human ELOVL fatty acid elongase 4 (ELOVL4)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADMD; CT118; ISQMR; SCA34; STGD2; STGD3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108083 sequence for NM_022726 edited (data generated by NextGen Sequencing)
ATGGGGCTCCTGGACTCGGAGCCGGGTAGTGTCCTAAACGTAGTGTCCACGGCACTCAAC GACACGGTAGAGTTCTACCGCTGGACCTGGTCCATCGCAGATAAGCGTGTGGAAAATTGG CCTCTGATGCAGTCTCCTTGGCCTACACTAAGTATAAGCACTCTTTATCTCCTGTTTGTG TGGCTGGGTCCAAAATGGATGAAGGACCGAGAACCTTTTCAGATGCGTCTAGTGCTCATT ATCTATAATTTTGGGATGGTTTTGCTTAACCTCTTTATCTTCAGAGAGTTATTCATGGGA TCATATAATGCGGGATATAGCTATATTTGCCAGAGTGTGGATTATTCTAATAATGTTCAT GAAGTCAGGATAGCTGCTGCTCTGTGGTGGTACTTTGTATCTAAAGGAGTTGAGTATTTG GACACAGTGTTTTTTATTCTGAGAAAGAAAAACAACCAAGTTTCTTTCCTTCATGTGTAT CATCACTGTACGATGTTTACCTTGTGGTGGATTGGAATTAAGTGGGTTGCAGGAGGACAA GCATTTTTTGGAGTCCAGTTGAATTCCTTTATCCATGTGATTATGTACTCATACTATGGG TTAACTGCATTTGGCCCATGGATTCAGAAATATCTTTGGTGGAAACGATACCTGACTATG TTGCAACTGATTCAATTCCATGTGACCATTGGGCACACGGCACTGTCTCTTTACACTGAC TGCCCCTTCCCCAAATGGATGCACTGGGCTCTAATTGCCTATGCAATCAGCTTCATATTT CTCTTTCTTAACTTCTACATTCGGACATACAAAGAGCCTAAGAAACCAAAAGCTGGAAAA ACAGCCATGAATGGTATTTCAGCAAATGGTGTGAGCAAATCAGAAAAACAACTCATGATA GAAAATGGAAAAAAGCAGAAAAATGGAAAAGCAAAAGGAGATTAA Clone variation with respect to NM_022726.3 554 c=>t >OriGene 5' read for NM_022726 unedited
GCTGGATTTGTAACCGACTTATATAGGCGGCACCGCAATTCGCACGAGGGCGCGAGGCTG CAGACTGGTGCAGCGCACTGTGCTGGCGGCTGGGCCTCCTCCACCTCCTCGTCTTTCTCC CGGGAACCTTGACGACGCCTTCCGCTTGGCCCTGCCTTCTGCCGCATCCCCGCCGCCGCG GCGCCTTGAGGAGCAGGAGAAGACGCAGCCTGTCCGCCGCCGTTAGAGGGGTTCCCGGCC GCCGCTCGCCCCGTCGGCCGCCACCGCCTCCGGGGTCAGCCCTCTCTCTGGGTCTCCGCT TTCTCCTGCCGCCAGCGCCCGCTCATCGCCGCGATGGGGCTCCTGGACTCGGAGCCGGGT AGTGTCCTAAACGTAGTGTCCACGGCACTCAACGACACGGTAGAGTTCTACCGCTGGACC TGGTCCATCGCAGATAAGCGTGTGGAAAATTGGCCTCTGATGCAGTCTCCTTGGCCTACA CTAAGTATAAGCACTCTTTATCTCCTGTTTGTGTGGCTGGGTCCAAAATGGATGAAGGAC CGAGAACCTTTTCAGATGCGTCTAGTGCTCATTATCTATAATTTTGGGATGGTTTTGCTT AACCTCTTTATCTTCAGAGAGTTATTCATGGGATCATATAATGCGGGATATAGCTATATT TGCCAGAGTGTGGATTATTCTAATAATGTTCATGAAGTCAGGATAGCTGCTGCTCTGTGG TGGTACTTTGTATCTAAAGGAGTTGAGTATTTGGCACAGTGTTTTTATTCTGAGAAAGAA AACACCCAAGTTCTTTCCTTCTGTGTATCATCACTGTACGAATGTTACCTTGTGGTGGAT GGAAATAAGTGGGTGCAAGAGGACAGCATTTTTGGAGTCCAGTGAATTCCTTATCATGTG ATATGTACTCTACTATGGTTACTGC >OriGene 3' read for NM_022726 unedited
CGCAATCTAGAGTCGAGNNNTTNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TCCCCCCAGCAAAAGTTTTTTATTGGGCTGAAATCAGGTACCAGGGAATGAATACCTTTT GGGAACCAGTCCAAAATGTTCACAAAGATTTACAAATTTCAGTCTTTACACACTGAGCAA CAAAACAAAGGGGTTGAATCCTTTTAAATCAAACTACTTTATATGTGGCAAATTTTCTGT AATTCTCATGACTGCATGCCTTTGGGGAAAAAGTTTTTAATTTTAATGCACAATAAATAT GTTATAGCTTACAAAATATTCTGAAATAGTTTGTACAAACAGAATACATCCTACACATGC AGTTTTGACATGTTGTTGAAATACTTAAAAAATATTCATGCTTTTTTTTGGCCACATTTT GTCTTTCTTTAGAAATCCCTTTGCAACATCCCTTAAAAAATTACCCTATGTAGTAAAACA TGATACAAATTTTTTCCTACTTTATTTCCAGTGGTTCACTTATATTACATGAAATACTTC ATTTGTAAATAGCAAATTGAATGTTATAGTTCGGACTACTCTCACTTTTATTCATTTGGG GTTTAAACAACACCTTGTAACATCAAGCTTTGAATTTAACATTCTTTACCACCAAGGAGT CAAGATTATTGCACCAAAATGGGTTTATACTTCATACCTAGTTAAAAATAAGATCTTGCA ACTTAGTCCAAGGAAAACGTTTCTCCCAAATAACCACTTTGAAGAGAGGGTNGTTNCACA GAATGTTGGGGTATGCTATTTGNCATAAAAGCAAAAAATTCTGNGGGATTTGAAAGTTAC ATTNAAATTACATTAAAAGACTCTGNTTTTTAATAAANTTTATTATTTTAATGTCCTTCC ACGANAAGTNGTATTTTTCATTTGAAATCGNACGGCTAATCAACANGAAGCTGGTAATAC TTTCTACGCCTANTGACTTCTTAGAGTCTAAAGAAGAGGGGTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_022726 |
| Insert Size | 2940 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022726.2, NP_073563.1 |
| RefSeq Size | 2992 bp |
| RefSeq ORF | 945 bp |
| Locus ID | 6785 |
| UniProt ID | Q9GZR5 |
| Domains | ELO |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Glycocalyx core protein Glypican 1 protects vessel wall endothelial cells from stiffness-mediated dysfunction and disease
,Mahmoud, M;Mayer, M;Cancel, LM;Bartosch, AM;Mathews, R;Tarbell, JM;,
Cardiovasc. Res.
,PubMed ID 32647868
[ELOVL4]
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| RG206248 | ELOVL4 (tGFP-tagged) - Human ELOVL fatty acid elongase 4 (ELOVL4) |
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