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USP2 (NM_004205) Human Untagged Clone
CAT＃: SC108156
USP2 (untagged)-Human ubiquitin specific peptidase 2 (USP2), transcript variant 1
CNY 4,512.00
CNY 9,790.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | UBP41; USP9 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108156 sequence for NM_004205 edited (data generated by NextGen Sequencing)
ATGTCCCAGCTCTCCTCCACCCTGAAGCGCTACACAGAATCGGCCCGCTACACAGATGCC CACTATGCCAAGTCGGGCTATGGTGCCTACACCCCGTCCTCCTATGGGGCCAATCTGGCT GCCTCCTTACTGGAGAAGGAGAAACTTGGTTTCAAGCCGGTCCCCACCAGCAGCTTCCTC ACCCGTCCCCGTACCTATGGCCCCTCCTCCCTCCTGGACTATGACCGGGGCCGCCCCCTG CTGAGACCCGACATCACTGGGGGTGGTAAGCGGGCAGAGAGCCAGACCCGGGGTACTGAG CGGCCTTTAGGCAGTGGCCTCAGCGGGGGCAGCGGATTCCCTTATGGAGTGACCAACAAC TGCCTCAGCTACCTGCCCATCAATGCCTATGACCAGGGGGTGACCCTAACCCAGAAGCTG GACAGCCAATCAGACCTGGCCCGGGATTTCTCCAGCCTCCGGACCTCAGATAGCTACCGG ATAGACCCCAGGAACCTGGGCCGCAGCCCCATGCTGGCCCGGACGCGCAAGGAGCTCTGC ACCCTGCAGGGGCTCTACCAGACAGCCAGCTGCCCTGAATACCTGGTCGACTACCTGGAG AACTATGGTCGCAAGGGCAGTGCATCTCAGGTGCCCTCCCAGGCCCCTCCCTCACGAGTC CCTGAAATCATCAGCCCAACCTACCGACCCATTGGCCGCTACACGCTGTGGGAGACGGGA AAGGGTCAGGCCCCTGGGCCCAGCCGCTCCAGCTCCCCGGGAAGAGACGGCATGAATTCT AAGAGTGCCCAGGGTCTGGCTGGTCTTCGAAACCTTGGGAACACGTGCTTCATGAACTCA ATTCTGCAGTGCCTGAGCAACACTCGGGAGTTGAGAGATTACTGCCTCCAGAGGCTCTAC ATGCGGGACCTGCACCACGGCAGCAATGCACACACAGCCCTCGTGGAAGAGTTTGCAAAA CTAATTCAGACCATATGGACTTCATCCCCCAATGATGTGGTGAGCCCATCTGAGTTCAAG ACCCAGATCCAGAGATACGCACCGCGCTTTGTTGGCTATAATCAGCAGGATGCTCAGGAG TTCCTTCGCTTTCTTCTGGATGGGCTCCATAACGAGGTGAACCGAGTGACACTGAGACCT AAGTCCAACCCTGAGAACCTCGATCATCTTCCTGATGACGAGAAAGGCCGACAGATGTGG AGAAAATATCTAGAACGGGAAGACAGTAGGATCGGGGATCTCTTTGTTGGGCAGCTAAAG AGCTCGCTGACGTGTACAGATTGTGGTTACTGTTCTACGGTCTTCGACCCCTTCTGGGAC CTCTCACTGCCCATTGCTAAGCGAGGTTATCCTGAGGTGACATTAATGGACTGCATGAGG CTCTTCACCAAAGAGGATGTGCTTGATGGAGATGAAAAGCCAACATGCTGTCGCTGCCGA GGCAGAAAACGGTGTATAAAGAAGTTCTCCATCCAGAGGTTCCCAAAGATCTTGGTGCTC CATCTGAAGCGGTTCTCAGAATCCAGGATCCGAACCAGCAAGCTCACAACATTTGTGAAC TTCCCCCTAAGAGACCTGGACTTAAGAGAATTTGCCTCAGAAAACACCAACCATGCTGTT TACAACCTGTACGCTGTGTCCAATCACTCCGGAACCACCATGGGTGGCCACTATACAGCC TACTGTCGCAGTCCAGGGACAGGAGAATGGCACACTTTCAACGACTCCAGCGTCACTCCC ATGTCCTCCAGCCAAGTGCGCACCAGCGACGCCTACCTGCTCTTCTACGAACTGGCCAGC CCGCCCTCCCGAATGTAG Clone variation with respect to NM_004205.4 >OriGene 5' read for NM_004205 unedited
AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGGTGGGAGA GAGTCAGGCAGGAGCCGAGGCCGGGGAGCCCTCTTCGTCAGCTGGTGCTCACTGCGCCGC GCCAGCGCCAGCCGGGACTCACCCGCAGCTCCATGCTTGTGCCCGGTTCGACTCGTCCAT CCTCCAAGAAGAGGCAGCCCATGAGGCTCCCAGTCCCCACTGAGTGCCACCCTGAAGGAT GTCCCAGCTCTCCTCCACCCTGAAGCGCTACACAGAATCGGCCCGCTACACAGATGCCCA CTATGCCAAGTCGGGCTATGGTGCCTACACCCCGTCCTCCTATGGGGCCAATCTGGCTGC CTCCTTACTGGAGAAGGAGAAACTTGGTTTCAAGCCGGTCCCCACCAGCAGCTTCCTCAC CCGTCCCCGTACCTATGGCCCCTCCTCCCTCCTGGACTATGACCGGGGCCGCCCCCTGCT GAGACCCGACATCACTGGGGGTGGTAAGCGGGCAGAGAGCCAGACCCGGGGTACTGAGCG GCCTTTAGGCAGTGGCCTCAGCGGGGGCAGCGGATTCCCTTATGGAGTGACCAACAACTG CCTCAGCTACCTGCCCATCAATGCCTATGACCACGGGGTGACCCTAACCCAGAAGCTGGA CAGCCAATCAGACCTGGCCCGGGATTTCTCCAGCCTCCGGACCTCATATAGCTACCGGAT AGACCCCAGGAACCTGGGCCGCAGCCCCATGCTGGCCCGGACGCGCCAAGAGCTCTGCAC CCTGGCAGGGCTCTACCANACAGCCAGCTGCCCTGAATACCTGGTCGACTACCTGGAGAA CTTGGGGCGCCAGGGCAGTGCATCTACAGTGCCCTCCCAGGCCCCCTCCCTCACGAGTCC CTGAAATCATTAGCCCAACCTACCGACCCATTTGGCCGCGTCCCCCTGTGGGGAGACCGG GAAAGGGTCATGCCCCTGGGCCCAGCCCCTCCACCTTCCGGGAAGGAACGCTTGGATTT >OriGene 3' genomic read for NM_004205 unedited
NCAACTATGNAACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTGATTT CTCAAANCTATTATTTATTCTGTACAAGGTTCCACTGTACATTAGACATTCTTCTACTCT TGCTTACACAGTAAACAAGTGTACACTTGCCCTTGGGCTCAGGTTCACAGGTCTTCTCTG GAGAAGGGTGTCAGGCCAGTAAAACTCAGGGTGTCTTTCTCTGATGCCTCCTCCTAGGAG CCTGGAATGTGCCAGGCTCCACGGGGCACAAGCCGGGCCCAGCTGTGTGGGTGAACAGCT TTACTCTCCAGGACAGCACAGAGTTTTATCCAACTATGTAGGGCAAAATTGAGCCCACAG GAAAGAACCATACAACTGAGGCAAGATGTCCCCAAATACCCAGGCTCCAGCTCCCAGGGC AGGACTGGAGACCAGCGCTAAGAAGAGCTGAGGGGTGGCCTGGGCATCCCTGAGAAACTC GGTCCAAAGGGCCTATTGTCTAGGAGGCTCTGAGAAGGGGGCGGGGGCAGGAAGGCCAGG GGGAAAGGGATGTTAAGAGAATAAATAAAAGGGAGAGAAGCTCTAGGGACGAGGGGCTTG TGCTATCCTTCAAACAGCTGGGGAGCAGACCANGGGTGGGCTAGAGGACGTGGGCGGGAA AGACTTGATGCCCTGTCNGAAGGAATCTACCTGCTTTCTTCTTTGCCTCACTGCAATGCA CAACGAGCCAAGGCTAAAGGCAGGATTCCCTTTCCCAGGCCGGTTTGAACAGAGCACTGG GGGAAAAAGGAAAAAGCTTGAGGGAAATTTTCGGGAGGGGCCAGTTACCCCCTGGGTCCC CAAATGCTTTAAAGCAACAATTCTGGGAGGCCACTTAATTTCCCTTCCAAACTTTAAAAA AAAAAAAAAAAAACCCCCACCCCCCAAAAAGAAACTTGGTTTAAATTCCAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004205 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004205.3, NP_004196.3 |
| RefSeq Size | 2633 bp |
| RefSeq ORF | 1818 bp |
| Locus ID | 9099 |
| UniProt ID | O75604 |
| Domains | UCH |
| Protein Families | Protease |
| Gene Summary | This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Ubiquitin-specific Cysteine Protease 2a (USP2a) Regulates the Stability of Aurora-A
,Yan Shi, Larry R. Solomon, Ana Pereda-Lopez, Vincent L. Giranda, Yan Luo, Eric F. Johnson, Alexander R. Shoemaker, Joel Leverson, and Xuesong Liu,
J. Biol. Chem., Nov 2011; 286: 38960 - 38968.
[USP2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200273 | USP2 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 2 (USP2), transcript variant 1 |
CNY 6,752.00 |
|
| RC200273L1 | Lenti ORF clone of Human ubiquitin specific peptidase 2 (USP2), transcript variant 1, Myc-DDK-tagged |
CNY 9,152.00 |
|
| RC200273L2 | Lenti ORF clone of Human ubiquitin specific peptidase 2 (USP2), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC200273L3 | Lenti ORF clone of Human ubiquitin specific peptidase 2 (USP2), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC200273L4 | Lenti ORF clone of Human ubiquitin specific peptidase 2 (USP2), transcript variant 1, mGFP tagged |
CNY 9,152.00 |
|
| RG200273 | USP2 (tGFP-tagged) - Human ubiquitin specific peptidase 2 (USP2), transcript variant 1 |
CNY 8,352.00 |
