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Aldolase (ALDOA) (NM_000034) Human Untagged Clone
CAT＃: SC108418
ALDOA (untagged)-Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALDA; GSD12; HEL-S-87p |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108418 sequence for NM_000034 edited (data generated by NextGen Sequencing)
ATGCCCTACCAATATCCAGCACTGACCCCGGAGCAGAAGAAGGAGCTGTCTGACATCGCT CACCGCATCGTGGCACCTGGCAAGGGCATCCTGGCTGCAGATGAGTCCACTGGGAGCATT GCCAAGCGGCTGCAGTCCATTGGCACCGAGAACACCGAGGAGAACCGGCGCTTCTACCGC CAGCTGCTGCTGACAGCTGACGACCGCGTGAACCCCTGCATTGGGGGTGTCATCCTCTTC CATGAGACACTCTACCAGAAGGCGGATGATGGGCGTCCCTTCCCCCAAGTTATCAAATCC AAGGGCGGTGTTGTGGGCATCAAGGTAGACAAGGGCGTGGTCCCCCTGGCAGGGACAAAT GGCGAGACTACCACCCAAGGGTTGGATGGGCTGTCTGAGCGCTGTGCCCAGTACAAGAAG GACGGAGCTGACTTCGCCAAGTGGCGTTGTGTGCTGAAGATTGGGGAACACACCCCCTCA GCCCTCGCCATCATGGAAAATGCCAATGTTCTGGCCCGTTATGCCAGTATCTGCCAGCAG AATGGCATTGTGCCCATCGTGGAGCCTGAGATCCTCCCTGATGGGGACCATGACTTGAAG CGCTGCCAGTATGTGACCGAGAAGGTGCTGGCTGCTGTCTACAAGGCTCTGAGTGACCAC CACATCTACCTGGAAGGCACCTTGCTGAAGCCCAACATGGTCACCCCAGGCCATGCTTGC ACTCAGAAGTTTTCTCATGAGGAGATTGCCATGGCGACCGTCACAGCGCTGCGCCGCACA GTGCCCCCCGCTGTCACTGGGATCACCTTCCTGTCTGGAGGCCAGAGTGAGGAGGAGGCG TCCATCAACCTCAATGCCATTAACAAGTGCCCCCTGCTGAAGCCCTGGGCCCTGACCTTC TCCTACGGCCGAGCCCTGCAGGCCTCTGCCCTGAAGGCCTGGGGCGGGAAGAAGGAGAAC CTGAAGGCTGCGCAGGAGGAGTATGTCAAGCGAGCCCTGGCCAACAGCCTTGCCTGTCAA GGAAAGTACACTCCGAGCGGTCAGGCTGGGGCTGCTGCCAGCGAGTCCCTCTTCGTCTCT AACCACGCCTATTAA Clone variation with respect to NM_000034.3 >OriGene 5' read for NM_000034 unedited
NTTGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGATTTATT TCTCTTGCAACCAAGGCCTCCGTCTGGATTTCCAAGGAAGAATTTCCTCTGAAGCACCGG AACTTGCTACTACCAGCACCATGCCCTACCAATATCCAGCACTGACCCCGGAGCAGAAGA AGGAGCTGTCTGACATCGCTCACCGCATCGTGGCACCTGGCAAGGGCATCCTGGCTGCAG ATGAGTCCACTGGGAGCATTGCCAAGCGGCTGCAGTCCATTGGCACCGAGAACACCGAGG AGAACCGGCGCTTCTACCGCCAGCTGCTGCTGACAGCTGACGACCGCGTGAACCCCTGCA TTGGGGGTGTCATCCTCTTCCATGAGACACTCTACCAGAAGGCGGATGATGGGCGTCCCT TCCCCCAAGTTATCAAATCCAAGGGCGGTGTTGTGGGCATCAAGGTAGACAAGGGCGTGG TCCCCCTGGCAGGGACAAATGGCGAGACTACCACCCAAGGGTTGGATGGGCTGTCTGAGC GCTGTGCCCAGTACAAGAAGGACGGAGCTGACTTCGCCAAGTGGCGTTGTGTGCTGAAGA TTGGGGAACACACCCCCTCAGCCCTCGCCATCATGGAAAATGCCAATGTTCTGGCCCGTT ATGCCAGTATCTGCCAGCAGAATGGCATTGTGCCCATCGTGGAGCCTGAGATCCTCCCTG ATGGGGACCATGACTTGAAGCGCTGCCAGTATGTGACCGAGAAGGTGCTGGCTGCTGTCT ACAAGGCTCTGAGTGACCACCACATCTACCTGGAAGGCACCTTGCTGAAGCCCACATGGG TCACCCAGCCATGCTGCCTTTCANAAGTTTCTCATGAGAGATGCCATGGCGACCGTCAAG CGCTGCGCCGACAGTGCCCCGCTGTACTGGGACACCTTCTGTCTGAGCAGAGGN >OriGene 3' read for NM_000034 unedited
TTTGAATACTGTTTATTTGGCTGTGTGCCGGAAAGGTGATGGACTTAGCATTCACATACG ACACCACACACCACTGTCACGAGGGAAGAAAGAGCGCGGGCAAGCCAGCCTGGAGCCCCG AGGAGGCGGCCTCCTCTTCAAGAGTGGGAGGGGGCAGGGCCTGGAGTGTTGGGGGCAGCC TGGGAACACCTCCGCTTAATAGGCGTGGTTAGAGACGAAGAGGGACTCGCTGGCAGCAGC CCCAGCCTGACCGCTCGGAGTGTACTTTCCTTGACAGGCAAGGCTGTTGGCCAGGGCTTC GCTTGACATACTCCTCCTGCGCAGCCTTCAGGTTCTCCTTCTTCCCGCCCCAGGCCTTCA GGGCAGAGGCCTGCAGGGCTCGGCCGTAGGAGAAGGTCAGGGCCCAGGGCTTCAGCAGGG GGCACTTGTTAATGGCATTGAGGTTGATGGACGCCTCCTCCTCACTCTGGCCTCCAGACA GGAAGGTGATCCCAGTGACAGCGGGGGGCACTGTGCGGCGCATCGCTGTGACGGTCGCCA TGGCAATCTCCTCATGAGAAAACTTCTGAGTGCAAGCATGGCCTGGGGTGACCATGTTGG GCTTCAGCAAGGTGCCTTCCAGGTAGATGTGGTGGTCACTCAGAGCCTTGTAGACAGCAG CCAGCACCTTCTCGGTCACATACTGGCAGCGCTTCAAGTCATGGTCCCCATCAGGGAGGA TCTCATGGCTCACGATGGGCACAATGCCATTCTGCTGGCAGATACTGGCATAACGGGCCA GAACATTGGCATTTTCCATGATGGCGATGGCTGAGGGGGTGTGTTCCCCCAATCTCAGCA CACAACGCCACTTGGCGAAAGTCAGCTCGTCCTTTCTGTACTGGGCACAGCGCTCAGACA GNCCATCCNACCCTTGGGTGGTAGTCTCGCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000034 |
| Insert Size | 1530 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000034.2, NP_000025.1 |
| RefSeq Size | 2353 bp |
| RefSeq ORF | 1095 bp |
| Locus ID | 226 |
| UniProt ID | P04075 |
| Domains | glycolytic_enzy |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway |
| Gene Summary | This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017] Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 2, 3, 4, 7, 8, 9, and 10 encode the same isoform. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis
,Kawai, K;Uemura, M;Munakata, K;Takahashi, H;Haraguchi, N;Nishimura, J;Hata, T;Matsuda, C;Ikenaga, M;Murata, K;Mizushima, T;Yamamoto, H;Doki, Y;Mori, M;,
Int. J. Oncol
,PubMed ID 28000858
[ALDOA]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202576 | ALDOA (Myc-DDK-tagged)-Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1 |
CNY 3,656.00 |
|
| RC202576L1 | Lenti ORF clone of Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202576L2 | Lenti ORF clone of Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC202576L3 | Lenti ORF clone of Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202576L4 | Lenti ORF clone of Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG202576 | ALDOA (tGFP-tagged) - Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1 |
CNY 5,256.00 |
|
| SC320738 | ALDOA (untagged)-Human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1 |
CNY 3,656.00 |
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