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MTRR (NM_002454) Human Untagged Clone
CAT＃: SC109461
MTRR (untagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1
CNY 5,120.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | cblE; MSR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109461 sequence for NM_002454 edited (data generated by NextGen Sequencing)
ATGAGGAGGTTTCTGTTACTATATGCTACACAGCAGGGACAGGCAAAGGCCATCGCAGAAGAAATATGTG AGCAAGCTGTGGTACATGGATTTTCTGCAGATCTTCACTGTATTAGTGAATCCGATAAGTATGACCTAAA AACCGAAACAGCTCCTCTTGTTGTTGTGGTTTCTACCACGGGCACCGGAGACCCACCCGACACAGCCCGC AAGTTTGTTAAGGAAATACAGAACCAAACACTGCCGGTTGATTTCTTTGCTCACCTGCGGTATGGGTTAC TGGGTCTCGGTGATTCAGAATACACCTACTTTTGCAATGGGGGGAAGATAATTGATAAACGACTTCAAGA GCTTGGAGCCCGGCATTTCTATGACACTGGACATGCAGATGACTGTGTAGGTTTAGAACTTGTGGTTGAG CCGTGGATTGCTGGACTCTGGCCAGCCCTCAGAAAGCATTTTAGGTCAAGCAGAGGACAAGAGGAGATAA GTGGCGCACTCCCGGTGGCATCACCTGCATCCTCGAGGACAGACCTTGTGAAGTCAGAGCTGCTACACAT TGAATCTCAAGTCGAGCTTCTGAGATTCGATGATTCAGGAAGAAAGGATTCTGAGGTTTTGAAGCAAAAT GCAGTGAACAGCAACCAATCCAATGTTGTAATTGAAGACTTTGAGTCCTCACTTACCCGTTCGGTACCCC CACTCTCACAAGCCTCTCTGAATATTCCTGGTTTACCCCCAGAATATTTACAGGTACATCTGCAGGAGTC TCTTGGCCAGGAGGAAAGCCAAGTATCTGTGACTTCAGCAGATCCAGTTTTTCAAGTGCCAATTTCAAAG GCAGTTCAACTTACTACGAATGATGCCATAAAAACCACTCTGCTGGTAGAATTGGACATTTCAAATACAG ACTTTTCCTATCAGCCTGGAGATGCCTTCAGCGTGATCTGCCCTAACAGTGATTCTGAGGTACAAAGCCT ACTCCAAAGACTGCAGCTTGAAGATAAAAGAGAGCACTGCGTCCTTTTGAAAATAAAGGCAGACACAAAG AAGAAAGGAGCTACCTTACCCCAGCATATACCTGCGGGATGTTCTCTCCAGTTCATTTTTACCTGGTGTC TTGAAATCCGAGCAATTCCTAAAAAGGCATTTTTGCGAGCCCTTGTGGACTATACCAGTGACAGTGCTGA AAAGCGCAGGCTACAGGAGCTGTGCAGTAAACAAGGGGCAGCCGATTATAGCCGCTTTGTACGAGATGCC TGTGCCTGCTTGTTGGATCTCCTCCTCGCTTTCCCTTCTTGCCAGCCACCACTCAGTCTCCTGCTCGAAC ATCTTCCTAAACTTCAACCCAGACCATATTCGTGTGCAAGCTCAAGTTTATTTCACCCAGGAAAGCTCCA TTTTGTCTTCAACATTGTGGAATTTCTGTCTACTGCCACAACAGAGGTTCTGCGGAAGGGAGTATGTACA GGCTGGCTGGCCTTGTTGGTTGCTTCAGTTCTTCAGCCAAACATACATGCATCCCATGAAGACAGCGGGA AAGCCCTGGCTCCTAAGATATCCATCTCTCCTCGAACAACAAATTCTTTCCACTTACCAGATGACCCCTC AATCCCCATCATAATGGTGGGTCCAGGAACCGGCATAGCCCCGTTTATTGGGTTCCTACAACATAGAGAG AAACTCCAAGAACAACACCCAGATGGAAATTTTGGAGCAATGTGGTTGTTTTTTGGCTGCAGGCATAAGG ATAGGGATTATCTATTCAGAAAAGAGCTCAGACATTTCCTTAAGCATGGGATCTTAACTCATCTAAAGGT TTCCTTCTCAAGAGATGCTCCTGTTGGGGAGGAGGAAGCCCCAGCAAAGTATGTGCAAGACAACATCCAG CTTCATGGCCAGCAGGTGGCGAGAATCCTCCTCCAGGAGAACGGCCATATTTATGTGTGTGGAGATGCAA AGAATATGGCCAAGGATGTACATGATGCCCTTGTGCAAATAATAAGCAAAGAGGTTGGAGTTGAAAAACT AGAAGCAATGAAAACCCTGGCCACTTTAAAAGAAGAAAAACGCTACCTTCAGGATATTTGGTCATAA Clone variation with respect to NM_002454.2 >OriGene 5' read for NM_002454 unedited
CAAACCCATTCGGCACGAGGGGAAGTCGCGTTGTGCAGGTTCGTGCCCGGCTGGCGCGGC GTGGTTTCACTGTTACATGCCTTGAAGTGATGAGGAGGTTTCTGTTACTATATGCTACAC AGCAGGGACAGGCAAAGGCCATCGCAGAAGAAATATGTGAGCAAGCTGTGGTACATGGAT TTTCTGCAGATCTTCACTGTATTAGTGAATCCGATAAGTATGACCTAAAAACCGAAACAG CTCCTCTTGTTGTTGTGGTTTCTACCACGGGCACCGGAGACCCACCCGACACAGCCCGCA AGTTTGTTAAGGAAATACAGAACCAAACACTGCCGGTTGATTTCTTTGCTCACCTGCGGT ATGGGTTACTGGGTCTCGGTGATTCAGAATACACCTACTTTTGCAATGGGGGGAAGATAA TTGATAAACGACTTCAAGAGCTTGGAGCCCGGCATTTCTATGACACTGGACATGCAGATG ACTGTGTAGGTTTAGAACTTGTGGTTGAGCCGTGGATTGCTGGACTCTGGCCAGCCCTCA GAAAGCATTTTAGGTCAAGCAGAGGACAAGAGGAGATAAGTGGCGCACTCCCGGTGGCAT CACCTGCATCCTCGAGGACAGACCTTGTGAAGTCAGAGCTGCTACACATTGAATCTCAAG TCGAGCTTCTGAGATTCGATGATTCAGGAAGAAAGGATTCTGAGGTTTTGAAGCANAATG CAGTGAACAGCAACCAATCCAATGTTGTAATTGAAGACTTTGAGTCCTCACTTACCCGTT CGGTACCCCCACTCTCACAAGCCTCTCTGAATATTCCTGGTTTACCCCCAGAATATTTAC AGGTACATCTGCAAGAGTC >OriGene 3' read for NM_002454 unedited
AAGCGCTGTTTTCATACCTTTTTTCAAAAGACAAAGCCTTCAACANANAGTTTTAAATCC CAAGCTATCAAATAAAAATACAATATATTATTAGAACAGTGNGAGAAAGATTATCATAAC ATTTTGTTTTGTTTGTGCAAATTATAACAGGGAATTAGACACTGGGAATCTAAAAATCCA AGGATACTAACTAAAGTCAGTATTTTAGGTCCAGCACACTGCTTGAGTGGTATCATGGAG ACAAATAATGTGGGAAAACTCAAAAATGTGCCAAGCAGCAGAAATAAAAGGAGTGAAAAT AAAAAGGTTGTATCTTTCTATTAAAATATGTACGTACTGGTACCTGTAAATTGAATGCAA ATGTCCCAAAATTCTGAAATTGTGACTTAAAAAAAAGTAATGGTGATAGATAAATCATAT GCCAGAGTGAAATTTTAAAATACATTTCATATTTCCAGCATCATAAAAATAAATCCCTCT GTAGGCAATTATCCTAAAATATTTTTTATCAGAAATATAGCTTTAGTAACAAATAACCAT TTGATAGTTACATAAACATATAACAGATATGCTCTACATGTGTAATTTAAGTACATTAAT ATGAGCATTCTTTATGGGTATACATCATATANAAATAAATCATTTTCATACTTTTTTAAA TGTTGGCACTGTTAGTCACAAGAATGAGCTACTCAGTCAGTCTCCCTATTTCAGGAAGCC CTTGCATGGNAAGACAGAGTCTCTGTGAAGTTCTCTGGGGAGTAAAGGAAGCGCTGATAG GGACTGAAGGCTGCCCTAGCTCAGAAGAGCTCAAGGCACAGGGCATTTGGGGAAGATCAC AAGCCCCAGGAAGGCGTAGATTGAAGATCCGTAAATCAAATCAGGAAATTTTGTTTAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002454 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002454.1, NP_002445.1 |
| RefSeq Size | 3317 bp |
| RefSeq ORF | 2097 bp |
| Locus ID | 4552 |
| UniProt ID | Q9UBK8 |
| Domains | flavodoxin, NAD_binding_1, FAD_binding_1 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208784 | MTRR (Myc-DDK-tagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1 |
CNY 3,990.00 |
|
| RC208784L3 | Lenti-ORF clone of MTRR (Myc-DDK-tagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1 |
CNY 5,890.00 |
|
| RC208784L4 | Lenti-ORF clone of MTRR (mGFP-tagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1 |
CNY 5,890.00 |
|
| RG208784 | MTRR (tGFP-tagged) - Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1 |
CNY 4,370.00 |
