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PTP alpha (PTPRA) (NM_002836) Human Untagged Clone
CAT＃: SC109671
PTPRA (untagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1
CNY 5,880.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109671 sequence for NM_002836 edited (data generated by NextGen Sequencing)
ATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAAC AATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCAACGGCA GAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCT GTGGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACTGTCAAT TCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACA ATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCC TGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCAGGTAAT TCTGACTCGAAGGACAGAAGAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCC TCTCTGCTAGTGATCGTGTTTATTATCATAGTTTTGTACATGTTAAGGTTTAAGAAATAC AAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCTTATCCAACGGCCGCACTGAGGATGTG GAGCCCCAGAGTGTGCCACTTCTGGCCAGATCCCCAAGCACCAACAGGAAATACCCACCC CTGCCCGTGGACAAGCTGGAAGAGGAAATTAACCGGAGAATGGCAGACGACAATAAGCTC TTCAGGGAGGAATTCAACGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCT TCCAAGGAGGAAAACAAGGAAAAAAATCGATATGTAAACATCTTGCCTTATGACCACTCT AGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTCATTC ATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACG GTGAATGATTTCTGGCGGATGATCTGGGAACAAAACACAGCCACCATCGTCATGGTTACC AACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTGCTGG ACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTA CGGAAGTTCTGCATCCAGCAGGTGGGCGACATGACCAACAGAAAGCCACAGCGCCTCATC ACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGGCATG CTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTC CACTGCAGTGCAGGTGTAGGGCGTACAGGTACCTTTGTCGTCATTGATGCCATGCTGGAC ATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGCACAG CGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAG CATTATCTCTATGGAGATACAGAACTGGAAGTGACCTCTCTAGAAACCCACCTGCAGAAA ATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAAGTTA ACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAG AAGAACCGTGTTTTACAGATCATTCCATATGAATTCAACAGAGTGATCATTCCAGTTAAG CGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCAGAAG GACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATG ATCTGGGAGTGGAAATCCTGCTCTATCGTGATGCTAACAGAACTGGAGGAGAGAGGCCAG GAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTACAGTG GAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAAC ACCAGGGAGAATAAGAGCCGGCAGATCCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTG GGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCAGCAG CAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGG ACCTTCTGTGCCCTGAGCACCGTCCTGGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTC TTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGAACAG TATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAAC TTCAAGTAA Clone variation with respect to NM_002836.3 >OriGene 5' read for NM_002836 unedited
AATACGACTCACTATAGGGCGGCCGCGACATTCGCACGAGGGCAGTTCAAATAACTAAGG ACACATGTTCAAAGAGCATAATTAACTTTTTAAAAGAAGCTAATAAGCATGGATTCCTGG TTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAACAATGCTACCACA GTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCAACGGCAGAACCAGTTAAA GAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCTGTGGCACCAACA TTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACTGTCAATTCTTCAGACTCT GACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACAATTTCACCAAAT GGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAAT TCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCAGGTAATTCTGACTCGAAG GACAGAAGAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGTAGTGA TCGTGTTATTATCATAGTTTTGTACATGTTAAGGTTTAAGAAATACAGCAGCTGGGAGCC TTCCAATTCTTTTCGCTTATCCAACGCCGACTGAAGATGTGGAGCCCCAAATGTGCCACT TCTGGCCAGATCCNCAGCACCACAGAANTACCCACCTTGCCCGTGACAGCTGGAAGAAGA AATAACCGAGAATGGCGACGACATAGCTCTCAGGNAGGATTCACGCTCTCCTGATGTCTA TCAGCCACTGGAAGCTGTTCCAGGGAGAAAACAGAAAAACGTTGTAACATCTGCTTTGAC ACTTTAAGCACTGACGNGGGGGGC >OriGene 3' read for NM_002836 unedited
NGGAATTACTGACACTTTTAATTCTCCATAAAACATGGNAAAAGGACTATCAGTGCTAAC ACATTTACATATAAAATTTCCACCTAATAGGTAATAGAAGCCTATGTACCAATTTCTAAA ACAGTTATAAGATATATACACAATTTGGGGTATATTAACAAAACAGAATATTACAAAATA TTAAAGGCAATCCTCCTGGTCCACGGACCCTTGTTGCCGCTTACTTGAAGTTGGCATAAT CTGAGAATGCATCAATATACTCCTGCACCACCTTGTAGCAGAACTCATACTGTTCCAGTG TCTGGACCATGTGTGGCCTCTGTAGCCGCAGGCTCTTGACAGTCTGGAAGACATCCAAAA TCCCCTCTGCTTTCACACGCTCCAGGACGGTGCTCAGGGCACAGAAGGTCCCCGTCCTTC CTGCCCCGGCGCTGCAGTGCACGGTGATGGGGTGGTTCCCTGACTGCTGCTGCTGCTTCT GCACGGCGGCGATGATGCTGATCATGCCCTTTCCGTCACTGGGGATGCCCACTTCAGGCC AGCCATGGAAGTGGAACTGCCGGATCTGCCGGCTCTTATTCTCCCTGGTGTTGGTGACCA GGAGGTCTCGGACGGTGTAGCTCTCACATTCCTCCTCCTTCTTCAGTTCCACTGTAATAT CTCCATAGGACACCAGTCCATCAGATGGCCAGTACTGGGCACACTTCTCCTGGCCTCTCT CCTTCAGTTCTGTTAGCATCACGATAGAGCAGGATTTCCACTCCCAGATCATTCGCCAGA AGTCCTCAATTGTGTGGGAGAGAAGGGCCCTGNCTGGCGATATANNGAGNCCTTCTGNCG GTAGCCATCAATAAGGNATGCGTCACATAGTCTGTATTCTCTTCGCCCCGCTTTACTGGA ATGATCACTCTGNTGAATNCATATGGATGATCTGTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002836 |
| Insert Size | 2820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002836.2, NP_002827.1 |
| RefSeq Size | 3643 bp |
| RefSeq ORF | 2409 bp |
| Locus ID | 5786 |
| UniProt ID | P18433 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222592 | PTPRA (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1 |
CNY 5,872.00 |
|
| RC222592L1 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, Myc-DDK-tagged |
CNY 8,272.00 |
|
| RC222592L2 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, mGFP tagged |
CNY 10,360.00 |
|
| RC222592L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, Myc-DDK-tagged |
CNY 10,360.00 |
|
| RC222592L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, mGFP tagged |
CNY 10,360.00 |
|
| RG222592 | PTPRA (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1 |
CNY 7,472.00 |
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