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EGLN2 (NM_080732) Human Untagged Clone
CAT＃: SC110740
EGLN2 (untagged)-Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3
CNY 1,200.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EIT-6; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_080732, the custom clone sequence may differ by one or more nucleotides
ATGGACAGCCCGTGCCAGCCGCAGCCCCTAAGTCAGGCTCTCCCTCAGTTACCAGGGTCTTCGTCAGAGC CCTTGGAGCCTGAGCCTGGCCGGGCCAGGATGGGAGTGGAGAGTTACCTGCCCTGTCCCCTGCTCCCCTC CTACCACTGTCCAGGAGTGCCTAGTGAGGCCTCGGCAGGGAGTGGGACCCCCAGAGCCACAGCCACCTCT ACCACTGCCAGCCCTCTTCGGGACGGTTTTGGCGGGCAGGATGGTGGTGAGCTGCGGCCGCTGCAGAGTG AAGGCGCTGCAGCGCTGGTCACCAAGGGGTGCCAGCGATTGGCAGCCCAGGGCGCACGGCCTGAGGCCCC CAAACGGAAATGGGCCGAGGATGGTGGGGATGCCCCTTCACCCAGCAAACGGCCCTGGGCCAGGCAAGAG AACCAGGAGGCAGAGCGGGAGGGTGGCATGAGCTGCAGCTGCAGCAGTGGCAGTGGTGAGGCCAGTGCTG GGCTGATGGAGGAGGCGCTGCCCTCTGCGCCCGAGCGCCTGGCCCTGGACTATATCGTGCCCTGCATGCG GTACTACGGCATCTGCGTCAAGGACAGCTTCCTGGGGGCAGCACTGGGCGGTCGCGTGCTGGCCGAGGTG GAGGCCCTCAAACGGGGTGGGCGCCTGCGAGACGGGCAGCTAGTGAGCCAGAGGGCGATCCCGCCGCGCA GCATCCGTGGGGACCAGATTGCCTGGGTGGAAGGCCATGAACCAGGCTGTCGAAGCATTGGTGCCCTCAT GGCCCATGTGGACGCCGTCATCCGCCACTGCGCAGGGCGGCTGGGCAGCTATGTCATCAACGGGCGCACC AAGGCCATGGTGGCGTGTTACCCAGGCAACGGGCTCGGGTACGTAAGGCACGTTGACAATCCCCACGGCG ATGGGCGCTGCATCACCTGTATCTATTACCTGAATCAGAACTGGGACGTTAAGGTGCATGGCGGCCTGCT GCAGATCTTCCCTGAGGGCCGGCCCGTGGTAGCCAACATCGAGCCACTCTTTGACCGGTTGCTCATTTTC TGGTCTGACCGGCGGAACCCCCACGAGGTGAAGCCAGCCTATGCCACCAGGTACGCCATCACTGTCTGGT ATTTTGATGCCAAGGAGCGGGCAGCAGCCAAAGACAAGTATCAGCTAGCATCAGGACAGAAAGGTGTCCA AGTACCTGTATCACAGCCGCCTACGCCCACCTAG >OriGene 5' read for NM_080732 unedited
TAATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGGGCCGGAG GAAAAACTCGCCACCCTGAAGGTCCCTTCCCAAGCCCTTAGGGACCGCAGAGGACTTGGG GACCAGCAAGCAACCCCCAGGGCACGAGAAGAGCTCTTGCTGTCTGCCCTGCCTCACCCT GCCCCACGCCAGGCCCGGTGGCCCCCAGCTGCATCAAGTGGAGGCGGAGGAGGAGGCGGA GGAGGGTGGCACCATGGGCCCGGGCGGTGCCCTCCATGCCCGGGGGATGAAGACACTGCT GCCATGGACAGCCCGTGCCAGCCGCAGCCCCTAAGTCAGGCTCTCCCTCAGTTACCAGGG TCTTCGTCAGAGCCCTTGGAGCCTGAGCCTGGCCGGGCCAGGATGGGAGTGGAGAGTTAC CTGCCCTGTCCCCTGCTCCCCTCCTACCACTGTCCAGGAGTGCCTAGTGAGGCCTCGGCA GGGAGTGGGACCCCCAGAGCCACAGCCACCTCTACCACTGCCAGCCCTCTTCGGGACGGT TTTGGCGGGCAGGATGGTGGTGAGCTGCGGCCGCTGCAGAGTGAAGGCGCTGCAGCGCTG GTCACCAAGGGGTGCCAGCGATTGGCAGCCCAGGGCGCACGGGCCTGAGCCCCCAAACGG AAATGGGCCGANGATGGTGGGGATGCCCCTTCACCAGCAAACGGCCCTGGGCCAGGCAAG AGAACCANGANGCANAGCGGGAGGGTGGCATGAGCTGCAGCTGCAGCAGTGGCAGTGGTG AAGCCAGNNTGCTGGCTGATGGAGAAGCGCTGNCCTCTGCGCCCGAGCGCCTGCCCTGGA CTATATCGTGCCCTGCATGCNGTACTACNGCATCTGCGTCAAGGACAGCTTNCTGGGGGC ANCACTGGNCNGTTCNCGTGCTTGGCCGAGGTGNAGGCCCTCAAAACGGGTGTGCCGCCT GCNAAACCGGCANCTAGTGAGGCANATGGCGATCCNGNCGNGCAGCATCCGTGGGGACC >OriGene 3' read for NM_080732 unedited
TGAACCGCCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGAGTGTGCAGC TCTGAGGTAAACTTTTATTTCTTGGCTGACAGGACTTCCACACCCATGCTCCTCCTGGCA CCTTTTACTCTGCCCAAGCAGTGGCAGCCCAGTCCAAAAGGTGCCTGCCATGGCCAAAGG GGTTGGGGAGTCACTTCACATTCCAGGCTGGAGGAGTGAGAGGACTTGGGGGTACTCCTC CCACCCCATTGCCAGCAAGAGGCCATGACTCACCTCAACCCCAAGTCCTGCATCCTGGTG GGAAGTGACAATGCCTCCTCCCAGCTCTCCATACCTAATGGGGTCATGACCAGACAGGGT AGGACCCAGGCCCCCAGCTTCAGTTGGTAACGGTGGCCTCCACGGCTGCCCCCTGTCCAG GTGACAACCCCAGCCCCCATGATGGGGCAGCAAAGGTCTCTTCTCCTCCTTGGTCCTCAG CAACAGACAGAGCCCTCCACACCAGGCAGGACAGAGGCAAAGTCAGAAGCAGCAGCGGTG GCAGGGAAGGAGCAGCCAGCACAGGCCCAGGGCTCTCCTGAAGTCATTTAAGCTGTCTGC CATGCGGCTCTGGGACTGGCCACTAGGTGGGCGTAGGCGGCTGTGATACAGGTACTTGGA CACCTTTCTGTCCTGATGCTAGCTGATACTTGTCTTTGGCTGCTGCCCGCTCCTTGGCAT CAAAATACCAGACAGTGATGGCGTACCTGGTGGCATANGCTGGCTTCACCTCGTGGGGGT TCCGCCGGTCAGACCCAAAATGAGCAACCCGTCAAAGATGGCTCGATGTGGCTACACGGG CCGGCCCTCAGGGAAGATCTGAGCAGGCCGCCTGCACCTTACGTCCCATTTCTGATCAGG TATAAATACGGTGATGCAACCCCCATTCCCTGGGGATTGTAACGTGCCTTAGTACCCAAG CCGTTGCCTGGTTAACACCACCAGGCCTGGTGCCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_080732 |
| Insert Size | 1750 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080732.1, NP_542770.1 |
| RefSeq Size | 2174 bp |
| RefSeq ORF | 378 bp |
| Locus ID | 112398 |
| UniProt ID | Q96KS0 |
| Domains | 2OG-FeII_Oxy, P4Hc |
| Protein Families | Druggable Genome |
| Protein Pathways | Pathways in cancer, Renal cell carcinoma |
| Gene Summary | The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (3) represents the longer transcript. Both variants 1 and 3 utilize alternative start codons that result in expression of two isoforms known as PHD1p43 and PHD1p40. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219191 | EGLN2 (Myc-DDK-tagged)-Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3 |
CNY 3,656.00 |
|
| RC219191L3 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219191L4 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3, mGFP tagged |
CNY 6,056.00 |
|
| RG219191 | EGLN2 (tGFP-tagged) - Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3 |
CNY 5,256.00 |
|
| SC317651 | EGLN2 (untagged)-Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 3 |
CNY 7,220.00 |
