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KCNK1 (NM_002245) Human Untagged Clone
CAT＃: SC110937
KCNK1 (untagged)-Human potassium channel, subfamily K, member 1 (KCNK1)
CNY 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110937 sequence for NM_002245 edited (data generated by NextGen Sequencing)
ATGCTGCAGTCCCTGGCCGGCAGCTCGTGCGTGCGCCTGGTGGAGCGGCACCGCTCGGCC TGGTGCTTCGGCTTCCTGGTGCTGGGCTACTTGCTCTACCTGGTCTTCGGCGCAGTGGTC TTCTCCTCGGTGGAGCTGCCCTATGAGGACCTGCTGCGCCAGGAGCTGCGCAAGCTGAAG CGACGCTTCTTGGAGGAGCACGAGTGCCTGTCTGAGCAGCAGCTGGAGCAGTTCCTGGGC CGGGTGCTGGAGGCCAGCAACTACGGCGTGTCGGTGCTCAGCAACGCCTCGGGCAACTGG AACTGGGACTTCACCTCCGCGCTCTTCTTCGCCAGCACCGTGCTCTCCACCACAGGTTAT GGCCACACCGTGCCCTTGTCAGATGGAGGTAAGGCCTTCTGCATCATCTACTCCGTCATT GGCATTCCCTTCACCCTCCTGTTCCTGACGGCTGTGGTCCAGCGCATCACCGTGCACGTC ACCCGCAGGCCGGTCCTCTACTTCCACATCCGCTGGGGCTTCTCCAAGCAGGTGGTGGCC ATCGTCCATGCCGTGCTCCTTGGGTTTGTCACTGTGTCCTGCTTCTTCTTCATCCCGGCC GCTGTCTTCTCAGTCCTGGAGGATGACTGGAACTTCCTGGAATCCTTTTATTTTTGTTTT ATTTCCCTGAGCACCATTGGCCTGGGGGATTATGTGCCTGGGGAAGGCTACAATCAAAAA TTCAGAGAGCTCTATAAGATTGGGATCACGTGTTACCTGCTACTTGGCCTTATTGCCATG TTGGTAGTTCTGGAAACCTTCTGTGAACTCCATGAGCTGAAAAAATTCAGAAAAATGTTC TATGTGAAGAAGGACAAGGACGAGGATCAGGTGCACATCATAGAGCATGACCAACTGTCC TTCTCCTCGATCACAGACCAGGCAGCTGGCATGAAAGAGGACCAGAAGCAAAATGAGCCT TTTGTGGCCACCCAGTCATCTGCCTGCGTGGATGGCCCTGCAAACCATTGA Clone variation with respect to NM_002245.3 >OriGene 5' read for NM_002245 unedited
GTCTTTGGGATTTTGTAACACGATTCACTATAGGGCGGACCGCGAATTCGCACGAGGCGG CGGGCCGCGCTCCGGCCGGTCTGCGGCGTTGGCCTTGGCGGCGGCGGTGGAGAAGATGCT GCAGTCCCTGGCCGGCAGCTCGTGCGTGCGCCTGGTGGAGCGGCACCGCTCGGCCTGGTG CTTCGGCTTCCTGGTGCTGGGCTACTTGCTCTACCTGGTCTTCGGCGCAGTGGTCTTCTC CTCGGTGGAGCTGCCCTATGAGGACCTGCTGCGCCAGGAGCTGCGCAAGCTGAAGCGACG CTTCTTGGAGGAGCACGAGTGCCTGTCTGAGCAGCAGCTGGAGCAGTTCCTGGGCCGGGT GCTGGAGGCCAGCAACTACGGCGTGTCGGTGCTCAGCAACGCCTCGGGCAACTGGAACTG GGACTTCACCTCCGCGCTCTTCTTCGCCAGCACCGTGCTCTCCACCACAGGTTATGGCCA CACCGTGCCCTTGTCAGATGGAGGTAAGGCCTTCTGCATCATCTACTCCGTCATTGGCAT TCCCTTCACCCTCCTGTTCCTGACGGCTGTGGTCCAGCGCATCACCGTGCACGTCACCCG CAGGCCGGTCCTCTACTTCCACATCCGCTGGGGCTTCTCCAAGCAAGTGGTGGCCATCGT CCATGCCGTGCTCCTTGAGTTTGTCACTGTGTCCTGCTTCTTCTCATCCCGGCCGCTGTC TTCTCAGTCCTGGAGGATGACTGGAACTTNCCTGGATCCTTTATTTTAGTTTATTTCCCT GAGCACCATTGGCCTGGGGGATTATGTGCCTGGGGAAAGGCTACATCAAAATTCAGAGAG CTCTATAGATTGGGATCACGTGTTACCTGCTACTTGGCCCTATTGCCTGTTGGTAGTNCT GGAAACCTTCTGTGGACTCATGAGCCTGAAAAATTCAGAAAAATGTCTAGTG >OriGene 3' read for NM_002245 unedited
GAACGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCGCAGAAGGTAGAAA CATTTATTGCAGCAGAATACTATGGTTATTCACTCTCAAGTTTATTATTCCCCTTATTTT ATTGTAGCAACTCTGGATTCTTTAGTATAAAGAGAAATCAAAAGAAACAAAATATCTATA GTCTTAGTTTCAGAACTACACTAGGATCTGGTGACCTAAACCATATGTACAGAATATAAA CATATTTATACTTTATATGTACATAGTTAATGGTTACCTATGCATTATAAATAGTAAGTT TAACTTAAATTCTACAAAAATAATCATTTTGGGTGGGTACATGCAAACCAGTACACATAA ACCTATTTATAAAACACATCTCTATGCTTTTTTTTTTTGCTTCTAAATATAAATTTTGCT ATTTAGCCATCAGCTAAATGATCTAAATGCAAACCCCAAAGTTTCCAGTTAAAAGTATAA AATCTGCTTCTAACCACAGCAGCATACTGCTTCAAGTATTCTCCTCCTATGTAAGGTCGA GATAATTTTGTCACATATGAATTTTAGGTGGACATCTCATTTCCTCACATATTAGACATC CTGCTGGGGTCACAGCTTCTTTGTTCCATTTGGCTTTTTTTGTTGTTTTTTAATAAGACA TTGCAAACAGTAGCTATTTCTTAAAGTGACATAATTTTCGCTTTTGCATTCTGATAAAAA TGAACATACTTAAGCCTCTTCCTTGCACCCTGACCCTGNTGCTCTAGCATAATGCAACAA ATCCTACGCTCAATGGGTTGCAAGGCCATCCAGCAGGCAGATGACTGGGTGGCCACAAAA AGCTCATTTTGCTNCTGGGCCTCTTTCATGCCAACTGGCTGGTCTGTGATCGAGGAAAAG GACAGTTGCCATGCTCTAATGAGGGCACTGAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002245 |
| Insert Size | 1870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002245.2, NP_002236.1 |
| RefSeq Size | 1901 bp |
| RefSeq ORF | 1011 bp |
| Locus ID | 3775 |
| UniProt ID | O00180 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels
,MECHANISMS OF SIGNAL TRANSDUCTION: Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels Zhaoyang Xiao, Pan-Yue Deng, Lalida Rojanathammanee, Chuanxiu Yang, Laurel Grisanti, Kannika Permpoonputtana, David Weinshenker, Van A. Doze, James E. Porter, and Saobo Lei,
J. Biol. Chem., Feb 2009; 10.1074/jbc.M806760200.
[KCNK1]
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Serotonin Inhibits Neuronal Excitability by Activating Two-pore Domain K+ Channels in the Entorhinal Cortex
,Pan-Yue Deng, Shree Kanta Poudel, Lalida Rojanathammanee, James E Porter, and Saobo Lei,
Mol Pharmacol. 2007 Jul;72(1):208-18.
[KCNK1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205321 | KCNK1 (Myc-DDK-tagged)-Human potassium channel, subfamily K, member 1 (KCNK1) |
CNY 3,656.00 |
|
| RC205321L3 | Lenti ORF clone of Human potassium channel, subfamily K, member 1 (KCNK1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205321L4 | Lenti ORF clone of Human potassium channel, subfamily K, member 1 (KCNK1), mGFP tagged |
CNY 5,890.00 |
|
| RG205321 | KCNK1 (tGFP-tagged) - Human potassium channel, subfamily K, member 1 (KCNK1) |
CNY 5,256.00 |
