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SCO2 (NM_005138) Human Untagged Clone
CAT＃: SC111130
SCO2 (untagged)-Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 2,400.00
CNY 6,270.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CEMCOX1; ECGF1; Gliostatin; MC4DN2; MYP6; PD-ECGF; SCO1L; TdRPase; TP; TYMP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111130 sequence for NM_005138 edited (data generated by NextGen Sequencing)
ATGCTGCTGCTGACTCGGAGCCCCACAGCTTGGCACAGGCTCTCTCAGCTCAAGCCTCCG GTCCTCCCTGGGACCCTGGGAGGCCAGGCCCTGCATCTGAGGTCCTGGCTTTTGTCAAGG CAGGGCCCTGCAGAGACAGGTGGGCAGGGCCAGCCCCAGGGCCCTGGGCTTCGAACCCGG CTGCTGATCACAGGCCTGTTCGGGGCTGGACTCGGTGGGGCCTGGCTGGCCCTGAGGGCT GAGAAGGAGAGGCTGCAGCAGCAAAAGCGAACAGAAGCCCTGCGCCAGGCAGCTGTGGGC CAGGGCGACTTCCACCTGCTGGATCACAGAGGCCGGGCTCGCTGCAAGGCTGACTTCCGG GGCCAGTGGGTGCTGATGTACTTTGGCTTCACTCACTGCCCTGACATCTGCCCAGACGAG CTGGAGAAGCTGGTGCAGGTGGTGCGGCAGCTGGAAGCAGAGCCTGGTTTGCCTCCAGTG CAGCCTGTCTTCATCACTGTGGACCCCGAGCGGGACGACGTTGAAGCCATGGCCCGCTAC GTCCAGGACTTCCACCCAAGACTGTTGGGTCTGACCGGCTCCACCAAACAGGTTGCCCAG GCTAGTCACAGTTACCGCGTGTACTACAATGCCGGCCCCAAGGATGAGGACCAGGACTAC ATCGTGGACCACTCCATTGCCATCTACCTGCTCAACCCTGACGGCCTCTTCACGGATTAC TACGGCCGGAGCAGATCGGCTGAGCAGATCTCAGACAGTGTGCGGCGGCACATGGCGGCT TTCCGCAGTGTCCTGTCTTGA Clone variation with respect to NM_005138.2 59 g=>c;633 a=>c >OriGene 5' read for NM_005138 unedited
CAGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGGCAAATAGA TAACGTGGTTAGTTCAGGCAAGGCATGCACTTGGAATGCTTTCCGTCAGCAAGAGGTTCA CCTTGCTGAGGTGCAGGTGCAGGTGCAGGGCAGGGTGCGGTGACAGGCTGGTGATCCCAG GTAGAGGACAGGAGTGACAGGTGTGGTTGCCCAGGTGTGGATGTTTGGTGGAGGTGGAGT TCTGAGCTCAGGTGAGCAGCTGCAAATGCCTGTTAAGCCTGAACGTGGGCTGGGTACTTC AGATGGGTGGCTGGTCTCAAGTCGCAGGGGCAGCCCAGGCACTGTCCTGGGCCTTCCCTT CTGGCTCCTGACGCCTGTGCTTGTTTCCAGGAGCATCAGATCCATGCTGCTGCTGACTCG GAGCCCCACAGCTTGGCACAGGCTCTCTCAGCTCAAGCCTCCGGTCCTCCCTGGGACCCT GGGAGGCCAGGCCCTGCATCTGAGGTCCTGGCTTTTGTCAAGGCAGGGCCCTGCAGAGAC AGGTGGGCAGGGCCAGCCCCAGGGCCCTGGGCTTCGAACCCGGCTGCTGATCACAGGCCT GTTCGGGGCTGGACTCGGTGGGGCCTGGCTGGCCCTGAGGGCTGAGAAGGAGAGGCTGCA GCAGCAAAAGCGAACAGAAGCCCTGCGCCAGGCAGCTGTGGGCCAGGGCGACTTCCACCT GCTGGNATCACAGAGCCGGGCTCGCTGCAAGGCTGACTTCCGGGGCCAGTGGGTGCTGAT GTACTTTGGCTNACTCACTGCCCTGACATCTGCCCAAACGAGCTGNANAANNCTGTGCAN GTGGTGCCGCANCTGAANCANAGCCTGTNTNGCCTCCAT >OriGene 3' read for NM_005138 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAACGCAGCCCGTTTAAT GATGGGGCCCAGACTGCAGTGGCTCAAGACAGGACACTGCGGAAAGCCGCCATGTGCCGC CGCACACTGTCTGAGATCTGCTCAGCCGATCTGCTCCGGCCGTAGTAATCCGTGAAGAGG CCGTCAGGGTTGAGCAGGTAGATGGCAATGGAGTGGTCCACGATGTAGTCCTGGTCCTCA TCCTTGGGGCCGGCATTGTAGTACACGCGGTAACTGTGACTAGCCTGGGCAACCTGTTTG GTGGAGCCGGTCAGACCCAACAGTCTTGGGTGGAAGTCCTGGACGTACCGGGCCATGGCT TCAACGTCGTCCCGCTCGGGGTCCACAGTGATGAACACAGGCTGCACTTGGAGCAAACCA GGCTCTGCTTCCAGCTGCCGCACCACCTGCACCACTTTTTCCACCTTGCTCTGGCCATAT GTTAGGGGCACTGATGCGACCCTAAGTTCATTCTTCCTCCCCTGATTTCCGGAATTACCT CCTCTTTCACCCCGATCCTTTGCTATCTAATTCCCGCAACCAATAATTCCTCTCTACGCC CCGGATATCGCCCCATTCCCCTTTTCCTTGTCCACATCTTCTCCTCCCCCGCTCTTTTCC CCCTCCATTTCCCTCTCCCCGTATTTCTGTTCCCCCCCCGTTTCGCTCCGGCCTTCCTAG TATACACCCCCTTCTCTCTTCACCTCTCTCCGCCCTCTCGCCCGTCCCCCAACTCTCCCT TACCCACCCATCCCTCCCCTCCTTCCATTCCACCCCCCCCTCCTCCCCCCTTTCCGTCAT CTCCCTCCTTCTCTCTCCTCCCCCTCTTTCTTCCCCCGCCCCACCCTATTCCCGACTTCC CTCCGTCNTATCTCCATCCCTTCTCTCCCCATGTTATTATTTCTCCGACTCCCCTATCTC ATTCTCCCTGACCTCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005138 |
| Insert Size | 1310 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005138.1, NP_005129.1 |
| RefSeq Size | 931 bp |
| RefSeq ORF | 801 bp |
| Locus ID | 9997 |
| UniProt ID | O43819 |
| Domains | SCO1-SenC |
| Protein Families | Druggable Genome |
| Gene Summary | Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014] Transcript Variant: This variant (1) represents the shortest transcript. Variants 1, 2, 3 and 4 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1–Trx Complex
,Esha Madan, Rajan Gogna, Periannan Kuppusamy, Madan Bhatt, Abbas Ali Mahdi, and Uttam Pati,
Mol. Cell. Biol., Apr 2013; 33: 1285 - 1302.
,PubMed ID 23319048
[SCO2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211837 | SCO2 (Myc-DDK-tagged)-Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 2,400.00 |
|
| RC211837L3 | Lenti ORF clone of Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211837L4 | Lenti ORF clone of Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG211837 | SCO2 (tGFP-tagged) - Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 4,000.00 |
