SNAP23 (NM_003825) Human Untagged Clone

CAT#: SC111720

SNAP23 (untagged)-Human synaptosomal-associated protein, 23kDa (SNAP23), transcript variant 1



  "NM_003825" in other vectors (7)

CNY 2,400.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-SNAP23 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms HsT17016; SNAP-23; SNAP23A; SNAP23B
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC111720 sequence for NM_003825 edited (data generated by NextGen Sequencing)
ATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCT
CTGGAAAGTACGAGGAGAATCCTGGGTTTAGCCATTGAGTCTCAGGATGCAGGAATCAAG
ACCATCACTATGCTGGATGAACAAAAGGAACAACTAAACCGCATAGAAGAAGGCTTGGAC
CAAATAAATAAGGACATGAGAGAGACAGAGAAGACTTTAACAGAACTCAACAAATGCTGT
GGCCTTTGTGTCTGCCCATGTAATAGAACAAAGAACTTTGAGTCTGGCAAGGCTTATAAG
ACAACATGGGGAGATGGTGGAGAAAACTCACCTTGCAATGTAGTATCTAAACAGCCAGGC
CCGGTGACAAATGGTCAGCTTCAGCAACCAACAACGGGAGCAGCCAGTGGTGGATACATT
AAACGCATAACTAATGATGCCAGAGAAGATGAAATGGAAGAGAACCTGACTCAAGTGGGC
AGTATCCTGGGAAATCTAAAAGACATGGCCCTGAACATAGGCAATGAGATTGATGCTCAA
AATCCACAAATAAAACGAATCACAGACAAGGCTGACACCAACAGAGATCGTATTGATATT
GCCAATGCCAGAGCAAAGAAACTCATTGACAGCTAA

Clone variation with respect to NM_003825.3
>OriGene 5' read for NM_003825 unedited
GTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGAGTTGCCGCCGGAGA
GGAGTGGCCTCGCCCGCTTGAGTTTTGATTCATCATGGATAATCTGTCATCAGAAGAAAT
TCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGG
TTTAGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAA
GGAACAACTAAACCGCATAGAAGAAGGCTTGGACCAAATAAATAAGGACATGAGAGAGAC
AGAGAAGACTTTAACAGAACTCAACAAATGCTGTGGCCTTTGTGTCTGCCCATGTAATAG
AACAAAGAACTTTGAGTCTGGCAAGGCTTATAAGACAACATGGGGAGATGGTGGAGAAAA
CTCACCTTGCAATGTAGTATCTAAACAGCCAGGCCCGGTGACAAATGGTCAGCTTCAGCA
ACCAACAACGGGAGCAGCCAGTGGTGGATACATTAAACGCATAACTAATGATGCCAGAGA
AGATGAAATGGAAGAGAACCTGACTCAAGTGGGCAGTATCCTGGGAAATCTAAAAGACAT
GGCCCTGAACATAGGCAATGAGATTGATGCTCAAAATCCACAAATAAAACGAATCACAGA
CAAGGCTGACACCAACAGAGATCGTATTGATATTGCCAATGCCAGAGCATAGAAACTATT
GACAGCTAAAGCTACTGCTGGTCCTTCTTATCATTTATTCACCTCCGTACCTCCTCCTTG
CAAGTTATTACCTTTTCAGAGTTTAAGTTTTCCGGTTCACGCTCCTCCTATCGGCAGATA
TATTGAAGAAAGGCCAGAGCAGTCCCAGCCTCCTTTTTTTTGTTTCTGTTGAGGCCGCCG
CTGCCTGCCTTCTCTANATTTNCTTCCCATCCACCCTAAATGGTTTC
>OriGene 3' read for NM_003825 unedited
GGGGGGCACCCNCCNCNTCTTTTNNANNNNAATCTTGNACGCGGCCGCATTCTANATCGA
GTTTTTTTTTTTTTTTTTTGTTAGTTAAAAAATTAATTGTAAGGATCAAGCAGTGGTTAT
TGGTGAAACCAATACACACTGACAGCTTTGAAGTGTTCAGATGCTAATTTTAAAATAAAT
GTGACAAATACCAATCAGATGTTCATAACACTTTTCAGGATCCACATCAACTTGATTATG
GACATAGTTCAATACACAAGGGTAAGAGAAAGAGTGTGTAATCACCAATAATTAAACCAG
AGGCATAATTTTTTCAAATAATTTTTAGTTACAGAATAAATTCTAACTTTTTAAAGTCTA
AAGCTACATAAAACTCAAAGCAATCTATTTTTCTACCTGAGGTCAAAATGACTTTCCTTT
TTCCTAACTAAACATAATTCTTAGCATTGAGGTAAATCTGAATTCATGTGGTATGCTTTG
TCAAACTTTTCCAAAAAATTTTAAGCCCTGCTTTAGAGAGAAATTCTCATGTTACACATA
TATATTTACATATTTTTTCNTCAAAGACTAATGANCATGTATGATGTTAATAGGCCTGTA
ATGGAACCATGATACTACTAATAATATGAAATANAAAGCCACTCATTTATATAAAGTGTT
CCTGAATGGTGCANNTAGAAATGGGATCACAGAATTATGTACATATATGAAATCACTTAG
AGTCAGAAATAAGCTCACTTTAAGAAAACTCAGCCAGGCACAGTGGCTACGCCTTGTATC
CAGTACTTTGGAAGGCCAGGCCGGTTGATCACGACGTCAGGAGTCCACGACCACTTGACA
TGGTGAACCCTGTTTTTACTAAAAAACAAAAATTACCCGACGGTGTGGACCACGCCTGTG
AATCCACCTCCTCAGGAGGCAGGGCAGAAAATTGCTGTGACCAGAGGCGGAGGTTCAATG
ACCCCAATCCCCCATGGGCCTCCAAACTGACAAAGAGGGAAACTTGACTCCN
Restriction Sites NotI-NotI     
ACCN NM_003825
Insert Size 2390 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003825.2, NP_003816.2
RefSeq Size 2307 bp
RefSeq ORF 636 bp
Locus ID 8773
UniProt ID O00161
Domains t_SNARE, SNAP-25
Protein Families Druggable Genome
Protein Pathways SNARE interactions in vesicular transport
Gene Summary Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) is the longer transcript, containing eight exons and encoding the full-length isoform (SNAP23A).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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