United States
Germany
Japan
United Kingdom
China
PDCD4 (NM_014456) Human Untagged Clone
CAT＃: SC111794
PDCD4 (untagged)-Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1
CNY 3,656.00
| Cited in 2 publications. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | H731 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111794 sequence for NM_014456 edited (data generated by NextGen Sequencing)
ATGGATGTAGAAAATGAGCAGATACTGAATGTAAACCCTGCAGATCCTGATAACTTAAGT GACTCTCTCTTTTCCGGTGATGAAGAAAATGCTGGGACTGAGGAAGTAAAGAATGAAATA AATGGAAATTGGATTTCAGCATCCTCCATTAACGAAGCTAGAATTAATGCCAAGGCAAAA AGGCGACTAAGGAAAAACTCATCCCGGGACTCTGGCAGAGGCGATTCGGTCAGCGACAGT GGGAGTGACGCCCTTAGAAGTGGATTAACTGTGCCAACCAGTCCAAAGGGAAGGTTGCTG GATAGGCGATCCAGATCTGGGAAAGGAAGGGGACTACCAAAGAAAGGTGGTGCAGGAGGC AAAGGTGTCTGGGGTACACCTGGACAGGTGTATGATGTGGAGGAGGTGGATGTGAAAGAT CCTAACTATGATGATGACCAGGAGAACTGTGTTTATGAAACTGTAGTTTTGCCTTTGGAT GAAAGGGCATTTGAGAAGACTTTAACACCAATCATACAGGAATATTTTGAGCATGGAGAT ACTAATGAAGTTGCGGAAATGTTAAGAGATTTAAATCTTGGTGAAATGAAAAGTGGAGTA CCAGTGTTGGCAGTATCCTTAGCATTGGAGGGGAAGGCTAGTCATAGAGAGATGACATCT AAGCTTCTTTCTGACCTTTGTGGGACAGTAATGAGCACAACTGATGTGGAAAAATCATTT GATAAATTGTTGAAAGATCTACCTGAATTAGCACTGGATACTCCTAGAGCACCACAGTTG GTGGGCCAGTTTATTGCTAGAGCTGTTGGAGATGGAATTTTATGTAATACCTATATTGAT AGTTACAAAGGAACTGTAGATTGTGTGCAGGCTAGAGCTGCTCTGGATAAGGCTACCGTG CTTCTGAGTATGTCTAAAGGTGGAAAGCGTAAAGATAGTGTGTGGGGCTCTGGAGGTGGG CAGCAATCTGTCAATCACCTTGTTAAAGAGATTGATATGCTGCTGAAAGAATATTTACTC TCTGGAGACATATCTGAAGCTGAACATTGCCTTAAGGAACTGGAAGTACCTCATTTTCAC CATGAGCTTGTATATGAAGCTATTATAATGGTTTTAGAGTCAACTGGAGAAAGTACATTT AAGATGATTTTGGATTTATTAAAGTCCCTTTGGAAGTCTTCTACCATTACTGTAGACCAA ATGAAAAGAGGTTATGAGAGAATTTACAATGAAATTCCGGACATTAATCTGGATGTCCCA CATTCATACTCTGTGCTGGAGCGGTTTGTAGAAGAATGTTTTCAGGCTGGAATAATTTCC AAACAACTCAGAGATCTTTGTCCTTCAAGGGGCAGAAAGCGTTTTGTAAGCGAAGGAGAT GGAGGTCGTCTTAAACCAGAGAGCTACTGA Clone variation with respect to NM_014456.4 106 a=>g >OriGene 5' read for NM_014456 unedited
TTGATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGAGAGACTCT CCGAGGCGGCGGCAGAGACAGAAGAGCGGGGTCGGGGCCGGCTGACCAGGAACCTGGGCG AGCAGCGGCGGGGGCCCGAGGGATTCTGAAGGAAGATTTCCATTAGGTAATTTGTTTAAT CAGTGCAAGCGAAATTAAGGGAAAATGGATGTAGAAAATGAGCAGATACTGAATGTAAAC CCTGCAGATCCTGATAACTTAAGTGACTCTCTCTTTTCCGGTGATGAAGAAAATGCTGGG ACTGAGGAAGTAAAGAATGAAATAAATGGAAATTGGATTTCAGCATCCTCCATTAACGAA GCTAGAATTAATGCCAAGGCAAAAAGGCGACTAAGGAAAAACTCATCCCGGGACTCTGGC AGAGGCGATTCGGTCAGCGACAGTGGGAGTGACGCCCTTAGAAGTGGATTAACTGTGCCA ACCAGTCCAAAGGGAAGGTTGCTGGATAGGCGATCCAGATCTGGGAAAGGAAGGGGACTA CCAAAGAAAGGTGGTGCATGAGGCAAAGGTGTCTGGGGTACACCTGGACAGGTGTATGAT GTGGAGGAGGTGGATGTGAAAGATCCTAACTATGATGATGACCAGGAGAACTGTGTTTAT GAAACTGTAGTTNTGCCTTTGGATGAAAGGGCATTTGAGAAGACTTTAACACCAATCATA CAGGAATATTTTGAGCATGGAGATACCTAATGAAGNTGCNGAAATGTTAANAGATTTAAA TCTTGGTGAAATGAANAGTGGAGTACCAGTGTTGGGCAGTATCCCTTANCATTGGAGGGG AANNGGCTAGTCATAGAGAGATGACATCTAAAGCTCTTTTCTGACCTTTGTGGNNACAGT ATGAGCACCACTGATGTGGGAAAATCATTTGATAAANTGTGGAAGGACTACCTGAATTAC ACTGGAACTCCTANACACCACAGTTGGTGGCCATTATGGCTANACTGGTGA >OriGene 3' read for NM_014456 unedited
GTACGCGGCCGCAATCTACAGTCGAGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAA AAATCAATACTGCTTCACATGTTTTATTTTGGGGCACATTCTTCTAAAACCAGGTTCATT TTTCCAGTTTTGTACAAAAATAGATGTTCCAGCCACCTTTTACTTAACTGGCTACCCTTT TAAAACCAATCATTATGTCCCCTGGAAAGATGAATAAGTCTCATGACTAATTTTTTAAAA ATTCTTTACGACAAAGAAATAACTTTCTTTTTTTACTCCCAAAGCACAGGTTCTCAACAG CAGCAGCCAACATGGGGTTTTATAAGTTTAACTTTACCCCCTAAATAAAGCCTTTGTATA AACCACGGATTTTACTACAAAAAACACTGTCCTTGAAAGAAAGGAGTGGCACTCAGACAT CAATGCAAAACTTGGAATGATTCGATCATAAACATGGCACTTACAAAAGGTAGCTTATTA AAATATCCCACTTAAAAAGAGGTCTACCTCTCTGGCCCTCCTTGCCCCCTCGAAACCCAA CCAACCCACAAACATTTCCTTTTAAAATTCCCCTTAAATGTGGCTTATAAAATGTCAGAA ATGCCTTGCCCCCAATACAACTGCTTTAAAAAAAAAAAAAAAACCCTGGGCCACACCCCT TTTCCCCTTCAAATTCTTATTTTCTATTACCACCCACAATCGGACGAGTTTCCTATTCTC AACTCCTCTCTCGGTCACACACAAACCTCACTCCTCCTTCATTCACAAATAGTTTTCTTC GCCCCTTCACAGGTACCAAATATTTCGTGGACCGCCTGGGGAAATTATTCCACTCGCGAG AAATCTTNTTTCCCAACAACCCGTTCCACGCCAGAACAGTTCAATGTGGGCCCCTTCAAC ATATTCTGGCCCCGATATTCTTTTGTTCATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014456 |
| Insert Size | 2640 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014456.3, NP_055271.2 |
| RefSeq Size | 3591 bp |
| RefSeq ORF | 1410 bp |
| Locus ID | 27250 |
| UniProt ID | Q53EL6 |
| Domains | MA3 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PDCD4 is an androgen-repressed tumor suppressor that regulates prostate cancer growth and castration resistance
,Zennami, K;Choi, SM;Liao, R;Li, Y;Dinalankara, W;Marchionni, L;Rafiqi, FH;Kurozumi, A;Hatano, K;Lupold, SE;,
Mol. Cancer Res.
,PubMed ID 30518628
[PDCD4]
|
|
CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation
,Pisano, A;Ceglia, S;Palmieri, C;Vecchio, E;Fiume, G;De Laurentiis, A;Mimmi, S;Falcone, C;Iaccino, E;Scialdone, A;Pontoriero, M;Fasanella Masci, F;Valea, R;Krishnan, S;Gaspari, M;Cuda, G;Scala, G;Quinto, I;,
J. Biol. Chem.
,PubMed ID 25882842
[PDCD4]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206016 | PDCD4 (Myc-DDK-tagged)-Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1 |
CNY 3,990.00 |
|
| RC206016L1 | Lenti ORF clone of Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC206016L2 | Lenti ORF clone of Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206016L3 | Lenti ORF clone of Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC206016L4 | Lenti ORF clone of Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG206016 | PDCD4 (tGFP-tagged) - Human programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1 |
CNY 4,370.00 |
