gamma Catenin (JUP) (NM_021991) Human Untagged Clone
CAT#: SC112564
JUP (untagged)-Human junction plakoglobin (JUP), transcript variant 2
CNY 5,464.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CTNNG; DP3; DPIII; PDGB; PG; PKGB |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC112564 sequence for NM_021991 edited (data generated by NextGen Sequencing)
ATGGAGGTGATGAACCTGATGGAGCAGCCTATCAAGGTGACTGAGTGGCAGCAGACATAC ACCTACGACTCGGGTATCCACTCGGGCGCCAACACCTGCGTGCCCTCCGTCAGCAGCAAG GGCATCATGGAGGAGGATGAGGCCTGCGGGCGCCAGTACACGCTCAAGAAAACCACCACT TACACCCAGGGGGTGCCCCCCAGCCAAGGTGATCTGGAGTACCAGATGTCCACAACAGCC AGGGCCAAACGGGTGCGGGAGGCCATGTGCCCTGGTGTGTCAGGCGAGGACAGCTCGCTT CTGCTGGCCACCCAGGTGGAGGGGCAGGCCACCAACCTGCAGCGACTGGCCGAGCCGTCC CAGCTGCTCAAGTCGGCCATTGTGCATCTCATCAACTACCAGGACGATGCCGAGCTGGCC ACTCGCGCCCTGCCCGAGCTCACCAAACTGCTCAACGACGAGGACCCGGTGGTGGTGACC AAGGCGGCCATGATTGTGAACCAGCTGTCGAAGAAGGAGGCGTCGCGGCGGGCCCTGATG GGCTCGCCCCAGCTGGTGGCCGCTGTCGTGCGTACCATGCAGAATACCAGCGACCTGGAC ACAGCCCGCTGCACCACCAGCATCCTGCACAACCTCTCCCACCACCGGGAGGGGCTGCTC GCCATCTTCAAGTCGGGTGGCATCCCTGCTCTGGTCCGCATGCTCAGCTCCCCTGTGGAG TCGGTCCTGTTCTATGCCATCACCACGCTGCACAACCTGCTCCTGTACCAGGAGGGCGCC AAGATGGCCGTGCGCCTGGCCGACGGGCTGCAAAAGATGGTGCCCCTGCTCAACAAGAAC AACCCCAAGTTCCTGGCCATCACCACCGACTGCCTGCAGCTCCTGGCCTACGGCAACCAG GAGAGCAAGCTGATCATCCTGGCCAATGGTGGGCCCCAGGCCCTCGTGCAGATCATGCGT AACTACAGTTATGAAAAGCTGCTCTGGACCACCAGTCGTGTGCTCAAGGTGCTATCCGTG TGTCCCAGCAATAAGCCTGCCATTGTGGAGGCTGGTGGGATGCAGGCCCTGGGCAAGCAC CTGACCAGCAACAGCCCCCGCCTGGTGCAGAACTGCCTGTGGACCCTGCGCAACCTCTCA GATGTGGCCACCAAGCAGGAGGGCCTGGAGAGTGTGCTGAAGATTCTGGTGAATCAGCTG AGTGTGGATGACGTCAACGTCCTCACCTGTGCCACGGGCACACTCTCCAACCTGACATGC AACAACAGCAAGAACAAGACGCTGGTGACACAGAACAGCGGTGTGGAGGCTCTCATCCAT GCCATCCTGCGTGCTGGTGACAAGGACGACATCACGGAGCCTGCCGTCTGCGCTCTGCGC CACCTCACTAGCCGCCACCCTGAGGCCGAGATGGCCCAGAACTCTGTGCGTCTCAACTAT GGCATCCCAGCCATCGTGAAGCTGCTCAACCAGCCCAACCAGTGGCCACTGGTCAAGGCA ACCATCGGCTTGATCAGGAATCTGGCCCTGTGCCCAGCCAACCATGCCCCGCTGCAGGAG GCAGCGGTCATCCCCCGCCTCGTCCAACTGCTGGTGAAGGCCCACCAGGATGCCCAGCGC CACGTAGCTGCAGGCACACAGCAGCCCTACACGGATGGTGTGAGGATGGAGGAGNNNNTG GAGGGCTGCACCGGAGCACTGCACATCCTCGCCCGGGACCCCATGAACCGCATGGAGATC TTCCGGCTCAACACCATTCCCCTGTTTGTGCAGCTCCTGTACTCGTCGGTGGAGAACATC CAGCGCGTGGCTGCCGGGGTGCTGTGTGAGCTGGCCCAGGACAAGGAGGCGGCCGACGCC ATTGATGCAGAGGGGGCCTCGGCCCCACTCATGGAGTTGCTGCACTCCCGCAACGAGGGC ACTGCCACCTACGCTGCTGCCGTCCTGTTCCGCATCTCCGAGGACAAGAACCCAGACTAC CGGAAGCGCGTGTCCGTGGAGCTCACCAACTCCCTCTTCAAGCATGACCCGGCTGCCTGG GAGGCTGCCCAGAGCATGATTCCCATCAATGAGCCCTATGGAGATGACTTGGATGCCACC TACCGCCCCATGTACTCCAGCGATGTGCCCCTTGACCCGCTGGAGATGCACATGGACATG GATGGAGACTACCCCATCGACACCTACAGCGACGGCCTCAGGCCCCCGTACCCCACTGCA GACCACATGCTGGCCTAG Clone variation with respect to NM_021991.2 1675 a=>n;1676 t=>n;1677 t=>n;1678 g=>n;2089 a=>t >OriGene 5' read for NM_021991 unedited
CTATCACCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCG AATTCGGCACGAGGGTCCGGAGCAGCCGCCGCCCGACCGCGCCGAGCTCAGTTCGCTGTC CGCGCCGGCTCCCACCCCGGCCCGACCCCGACCCGGCCCGGTCAGGCCCCATACTCAGTA GCCACGATGGAGGTGATGAACCTGATGGAGCAGCCTATCAAGGTGACTGAGTGGCAGCAG ACATACACCTACGACTCGGGTATCCACTCGGGCGCCAACACCTGCGTGCCCTCCGTCAGC AGCAAGGGCATCATGGAGGAGGATGAGGCCTGCGGGCGCCAGTACACGCTCAAGAAAACC ACCACTTACACCCAGGGGGTGCCCCCCAGCCAAGGTGACCTGGAGTACCAGATGTCCACA ACAGCCAGGGCCAAACGGGTGCGGGAGGCCATGTGCCCTGGTGTGTCAGGCGAGGACAGC TCGCTTCTGCTGGCCACCCAGGTGGAGGGGCAGGCCACCAACCTGCAGCGACTGGCCGAG CCGTCCCAGCTGCTCAAGTCGGCCATTGTGCATCTCATCAACTACCAGGACGATGCCGAG CTGGCCACTCGCGCCCTGCCCGAGCTCACCAAACTGCTCAACGACGAGGACCCGGTGGTG GTGACCAANGCGGCCATGATTGTGAACCAGCTGTCGAAGAAGGAGCGTCGCGGCGGGCCC TGATGGGCTCGCCCCAGCTGGTGGCCGCTGTCGTGCGTACCATGCAGAATACCAGCGACC TGGACACAGNCCGCTGCACAACAGCATCCTGCACACCTCTCCCACACCGGGAGGGGCTGC TCGCCATCTTCAAGTCGA >OriGene 3' read for NM_021991 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCATCTGTGTTATTTTTATTTTC TTTGCTTTGGTCTATACAAAAAAACCAATAACCAAAAACATAAAGCGATAATAATAAAAC ACTCTGCTTGGACCTCCCCCAGCCCCCCACACCATGTGCGGGAAATGGGGGGGTCTGAAA CAGGAAGGGGAAGAGAAAGCCCCTCACCACACACCAGAGGGGTCAGCCAAGAGCACTTCT CGGGGTCAGCTAGGGCAGCTGTGTGGGTGGGACAGGGGTGTGAGGAAGCTGTCCCCAGAG CTCCCTGGGGAGTGAGGGGTGGGCAAAGCCAACTAAGCACCCTGGAGAGAGAAGCTGGCA TCTTCTGGAGCAGGTGACTCACTCCATATCTCCTCCCCATCTCCCCTGGACGGTCCCTGA ACTTTTCAAGAGAAGTTTTGGATTTTGGGGGTTTGGGTCTCGAACCTGGGCCCTGGAGGC CCTGAGGGCTTAGGGCAGTTGGTCGGTGGAGTTCAGTGAGAAAATCAGACCCAGAGAAGG AACCAAAGCCCTTCCGGGGCCCAGGCAGCTGGAGACAGGGAGGCTGGAGGTTTGNAGGGG CGTTGCTGGGGGAAACAGAATGGTACTTGAGTCTGAAGCTTTATTGCCCAGGCCCAGGGG CGGGGAGGGGGGTGCATGCCCTGGCCCCTGCCCAGACAGAAAACAGGACAGACCCTTTCC CAGAAAGACCCTCGGAGACCCTTGAAGCCCAGGTGCACCAGAATTACACCCCGTTCCCCA GCTAGCATTTTTTGCTTGCCCTTGCCTGGACGAAACCTTTAAAGAGGAACGCACTGGGCC ACGCCCCTAGCCACTTGTGGTTTCAATGGGGTCCCGGGCCCCGAGCCCCCCTTTTGGGTC CAAGGGGGGACCCTCTCCTTTGCCGTGTTTTTCCC |
Restriction Sites | NotI-NotI |
ACCN | NM_021991 |
Insert Size | 3240 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_021991.1, NP_068831.1 |
RefSeq Size | 3192 bp |
RefSeq ORF | 2238 bp |
Locus ID | 3728 |
UniProt ID | P14923 |
Domains | Armadillo_seg |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer |
Gene Summary | This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate segment in the 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219207 | JUP (Myc-DDK-tagged)-Human junction plakoglobin (JUP), transcript variant 2 |
CNY 5,456.00 |
|
RC219207L3 | Lenti ORF clone of Human junction plakoglobin (JUP), transcript variant 2, Myc-DDK-tagged |
CNY 7,700.00 |
|
RC219207L4 | Lenti ORF clone of Human junction plakoglobin (JUP), transcript variant 2, mGFP tagged |
CNY 7,700.00 |
|
RG219207 | JUP (tGFP-tagged) - Human junction plakoglobin (JUP), transcript variant 2 |
CNY 6,370.00 |
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