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ACKR3 (NM_020311) Human Untagged Clone
CAT＃: SC112665
CXCR7 (untagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7)
CNY 3,656.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112665 sequence for NM_020311 edited (data generated by NextGen Sequencing)
ATGGATCTGCATCTCTTCGACTACTCAGAGCCAGGGAACTTCTCGGACATCAGCTGGCCA TGCAACAGCAGCGACTGCATCGTGGTGGACACGGTGATGTGTCCCAACATGCCCAACAAA AGCGTCCTGCTCTACACGCTCTCCTTCATTTACATTTTCATTTTCGTCATCGGCATGATT GCCAACTCCGTGGTGGTCTGGGTGAATATCCAGGCCAAGACCACAGGCTATGACACGCAC TGCTACATCTTGAACCTGGCCATTGCCGACCTGTGGGTTGTCCTCACCATCCCAGTCTGG GTGGTCAGTCTCGTGCAGCACAACCAGTGGCCCATGGGCGAGCTCACGTGCAAAGTCACA CACCTCATCTTCTCCATCAACCTCTTCGGCAGCATTTTCTTCCTCACGTGCATGAGCGTG GACCGCTACCTCTCCATCACCTACTTCACCAACACCCCCAGCAGCAGGAAGAAGATGGTA CGCCGTGTCGTCTGCATCCTGGTGTGGCTGCTGGCCTTCTGCGTGTCTCTGCCTGACACC TACTACCTGAAGACCGTCACGTCTGCGTCCAACAATGAGACCTACTGCCGGTCCTTCTAC CCCGAGCACAGCATCAAGGAGTGGCTGATCGGCATGGAGCTGGTCTCCGTTGTCTTGGGC TTTGCCGTTCCCTTCTCCATTATCGCTGTCTTCTACTTCCTGCTGGCCAGAGCCATCTCG GCGTCCAGTGACCAGGAGAAGCACAGCAGCCGGAAGATCATCTTCTCCTACGTGGTGGTC TTCCTTGTCTGCTGGCTGCCCTACCACGTGGCGGTGCTGCTGGACATCTTCTCCATCCTG CACTACATCCCTTTCACCTGCCGGCTGGAGCACGCCCTCTTCACGGCCCTGCATGTCACA CAGTGCCTGTCGCTGGTGCACTGCTGCGTCAACCCTGTCCTCTACAGCTTCATCAATCGC AACTACAGGTACGAGCTGATGAAGGCCTTCATCTTCAAGTACTCGGCCAAAACAGGGCTC ACCAAGCTCATCGATGCCTCCAGAGTCTCAGAGACGGAGTACTCTGCCTTGGAGCAGAGC ACCAAATGA Clone variation with respect to NM_020311.2 162 c=>t >OriGene 5' read for NM_020311 unedited
NTTGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGAAGGGAG CCAGCGCACAGCACAGCCAGGAAGGCGAGCGAGCCCAGCCAGCCCAGCCAGCCCAGCCAG CCCGGAGGTCATTTGATTGCCCGCCTCAGAACGATGGATCTGCATCTCTTCGACTACTCA GAGCCAGGGAACTTCTCGGACATCAGCTGGCCATGCAACAGCAGCGACTGCATCGTGGTG GACACGGTGATGTGTCCCAACATGCCCAACAAAAGCGTCCTGCTCTACACGCTCTCCTTC ATTTACATTTTCATTTTCGTCATCGGCATGATTGCCAACTCCGTGGTGGTCTGGGTGAAT ATCCAGGCCAAGACCACAGGCTATGACACGCACTGCTACATCTTGAACCTGGCCATTGCC GACCTGTGGGTTGTCCTCACCATCCCAGTCTGGGTGGTCAGTCTCGTGCAGCACAACCAG TGGCCCATGGGCGAGCTCACGTGCAAAGTCACACACCTCATCTTCTCCATCAACCTCTTC GGCAGCATTTTCTTCCTCACGTGCATGAGCGTGGACCGCTACCTCTCCATCACCTACTTC ACCAACACCCCCAGCAGCAGGAAGAAGATGGTACGCCGTGTCGTCTGCATCCTGGTGTGG CTGCTGGCCTTCTGCGTGTCTCTGCCTGACACCTACTACCTGAAGACCGTCACGTCTGCG TCCAACAATGAGACCTACTGCCGGTCCTTCTACCCCGAGCACAGCATCAAGGAGTGGCTG ATCGGCATGGAGCTGGTCTNCGTTGTCTTGGGCTNTGCCGTTCCCTTCTNCTTATCGCTG TCTTCTACTTNCTGCTGGCCAGAGCCATCTCGCGTCCAGTGACCCAGAGAGCACAGCAGC CGGAGACATCTCNTCTACGTGGTGGGCTTCCTTG >OriGene 3' read for NM_020311 unedited
CCTTTTTAACTATGNACCGCGGCNCGTATTCTCATGATCGGTCCTTTTTTTTTTTTTTTT AGGAAACAAAAATTTTTATTAAAAAACTTCACTTACACATTGCGTAGAATATCTGAAATG CAACTGCTCGTTGCGTGTGCAGATCCGTAGTTTCAGCAACAGCCCCCCCCGCGATCGCTA AATGTACCTTTACACTACTATTAATGTGACAAACTGCATTACACAGCAGTTCTCGCTTCA TATCCCGCGCCGGTACAACCCACCACACATCTTTTCAACCATGGTCCATAACACATCGCA GCCTCCCACTGCTATCCATCTCCCTCCTCCCTTACTCCCACTCCTACCTCCTTGTTCCCC TCCTCTCTCGTCTCTGTCATTCTTCCCCCCATTTCCACGTTTTGCCCACCCTCAAAACCA CACCCACTCTGAATATATGCTAGCATTTATGTCTGTGTTACAATACCCACCATATAGTTA CACCCCCCACTCCTCTCACCAGGCCCACCTATTCTGCATAACTACCGCGCTCATCCCTAC TCCCTTCGCCCCTCGCCAATCCTTTGCCCCCTTGACTTCCCCACCTTCCCGTATCTTCAG TTTTCGTCTGCCCTCCCCCTCGCCTCTGACTCATTTTCTTGTCGGTGTACCCAAGCGCCG ACTGCCGATAACCTGTCGCGCCGTTAAGTCCAATGTAAGCCTGGGCCCTTCCAAAACGTA AGTACGTTCGCACCCCCCCCCCGTCGCCCTTACCTTCACGCGGCCTGAACTATGGGGGCA CTTCGTTTGTCTTATTCCCCCCCGGCTTCTTCCGTGCTTGTACCCAACCATACTTTCCTT TATTTTCTTTCGCATTACCATCCGGGGCCTGTTCCAGTTTCCACCCCCCTCCTTTCAACC TGTAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_020311 |
| Insert Size | 2090 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020311.1, NP_064707.1 |
| RefSeq Size | 2064 bp |
| RefSeq ORF | 1089 bp |
| Locus ID | 57007 |
| UniProt ID | P25106 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Gene Summary | This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans
,Whitman, MC;Miyake, N;Nguyen, EH;Bell, JL;Matos Ruiz, PM;Chan, WM;Di Gioia, SA;Mukherjee, N;Barry, BJ;Bosley, TM;Khan, AO;Engle, EC;,
Hum. Mol. Genet.
,PubMed ID 31211835
[ACKR3]
|
|
Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12
,Del Molino Del Barrio, I;Wilkins, GC;Meeson, A;Ali, S;Kirby, JA;,
Int J Mol Sci
,PubMed ID 30441765
[ACKR3]
|
|
The IL-8–Regulated Chemokine Receptor CXCR7 Stimulates EGFR Signaling to Promote Prostate Cancer Growth
,Rajendra Kumar Singh and Bal L. Lokeshwar,
Cancer Res., May 2011; 71: 3268 - 3277
[ACKR3]
|
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Resources
Other Versions
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| RC206092L2 | Lenti-ORF clone of CXCR7 (mGFP-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7) |
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| RC206092L3 | Lenti-ORF clone of CXCR7 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7) |
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| RC206092L4 | Lenti-ORF clone of CXCR7 (mGFP-tagged)-Human chemokine (C-X-C motif) receptor 7 (CXCR7) |
CNY 7,888.00 |
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| RG206092 | CXCR7 (tGFP-tagged) - Human chemokine (C-X-C motif) receptor 7 (CXCR7) |
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