XYLT2 (NM_022167) Human Untagged Clone
CAT#: SC112785
XYLT2 (untagged)-Human xylosyltransferase II (XYLT2)
CNY 6,344.00
CNY 7,220.00
Cited in 1 publication. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | PXYLT2; SOS; XT-II; XT2; xylT-II |
Vector | pCMV6-XL6 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC112785 sequence for NM_022167 edited (data generated by NextGen Sequencing)
ATGGTGGCGAGCGCGCGAGTGCAGAAGCTGGTGCGGCGCTACAAGCTGGCGATTGCCACG GCGCTGGCCATCCTGCTGCTGCAGGGCCTGGTAGTGTGGAGCTTCAGCGGCCTGGAGGAG GACGAGGCGGGCGAGAAAGGAAGGCAGAGGAAGCCACGGCCACTGGACCCTGGCGAAGGT TCCAAGGACACAGACAGTTCAGCAGGGCGACGGGGCAGCACAGGCAGAAGGCATGGGCGC TGGCGGGGCCGTGCTGAGAGCCCAGGAGTGCCCGTGGCCAAGGTGGTACGGGCAGTAACC AGCCGGCAGAGAGCCAGCCGGCGGGTCCCACCTGCCCCACCTCCGGAAGCCCCAGGCCGC CAGAACCTGAGTGGGGCAGCAGCTGGGGAGGCGCTGGTAGGGGCAGCTGGCTTCCCACCA CACGGAGATACAGGGAGCGTGGAGGGCGCCCCCCAGCCCACGGACAATGGCTTCACCCCC AAGTGCGAGATCGTGGGCAAGGACGCACTGTCTGCACTGGCCCGGGCCAGCACCAAGCAG TGCCAGCAGGAGATCGCCAATGTGGTGTGCCTGCACCAGGCTGGGAGCCTCATGCCCAAG GCTGTGCCCCGGCACTGTCAGCTGACTGGGAAGATGAGCCCCGGCATCCAGTGGGATGAG AGCCAAGCCCAGCAGCCCATGGATGGCCCCCCGGTGCGAATCGCCTACATGCTGGTGGTT CACGGCCGCGCCATCCGCCAGCTGAAGCGTCTCCTCAAGGCCGTTTATCACGAGCAGCAC TTCTTTTACATCCATGTGGACAAGCGTTCCGACTACCTGCACCGGGAGGTGGTGGAGCTG GCCCAGGGCTATGATAACGTGCGGGTGACGCCCTGGCGCATGGTTACCATCTGGGGCGGG GCCAGCCTCCTGACGATGTACCTGCGGAGCATGCGGGACCTGCTAGAGGTGCCTGGCTGG GCCTGGGACTTCTTCATCAACCTCAGTGCCACTGACTATCCAACCAGGACCAATGAGGAG CTGGTGGCATTCCTATCCAAGAACCGGGACAAGAATTTCCTCAAGTCACATGGCCGGGAC AACTCCAGGTTCATCAAGAAACAGGGCCTGGACCGGCTCTTCCATGAGTGCGACTCACAC ATGTGGCGCCTGGGCGAGCGGCAGATCCCAGCAGGCATTGTGGTGGATGGCGGTTCTGAC TGGTTCGTGCTGACACGCAGCTTTGTGGAGTATGTGGTGTACACAGATGACCCGCTTGTG GCCCAGCTGCGCCAGTTCTACACATACACACTGCTCCCAGCCGAGTCCTTCTTCCACACG GTGCTGGAGAACAGCCTGGCCTGTGAGACCCTCGTGGACAACAACCTGCGGGTCACCAAC TGGAACCGCAAGCTGGGCTGCAAGTGCCAGTACAAGCACATTGTGGACTGGTGTGGCTGC TCCCCCAACGACTTCAAGCCACAGGACTTCCTCCGGCTGCAGCAAGTCTCCAGACCCACC TTCTTCGCCCGGAAGTTCGAGTCGACTGTGAACCAGGAGGTGCTGGAAATCCTGGACTTC CACCTGTACGGCAGCTACCCCCCCGGCACGCCAGCCCTCAAGGCCTACTGGGAGAACACC TACGACGCGGCTGATGGCCCCAGTGGGCTCAGTGATGTCATGCTCACTGCTTACACAGCC TTCGCCCGCCTCAGCCTGCACCATGCCGCCACTGCTGCACCCCCAATGGGCACCCCACTC TGCAGGTTTGAGCCCAGGGGCTTGCCGTCCAGCGTGCACCTGTATTTCTATGACGACCAT TTCCAGGGCTACCTGGTGACGCAGGCGGTGCAGCCCTCAGCCCAGGGGCCGGCAGAGACG CTTGAGATGTGGCTGATGCCCCAAGGGTCGCTGAAGCTGTTGGGGCGCAGTGACCAGGCC AGCCGGCTCCAGAGTCTGGAGGTTGGCACTGATTGGGACCCCAAAGAGCGTCTTTTCCGG AACTTTGGGGGGTTACTGGGGCCGCTGGACGAGCCTGTGGCCGTGCAGCGCTGGGCCCGG GGCCCCAACCTCACAGCCACAGTGGTCTGGATCGACCCAACCTATGTGGTGGCCACATCT TATGACATCACAGTAGATACGGAGACTGAGGTCACGCAATACAAGCCCCCACTGAGCCGG CCCCTGCGGCCAGGGCCCTGGACTGTTCGACTCCTTCAGTTCTGGGAACCGCTGGGTGAG ACCCGCTTCCTTGTGCTGCCCTTGACCTTCAACCGCAAACTACCTCTCAGGAAAGATGAT GCCAGCTGGCTGCACGCAGGGCCACCCCACAACGAGTACATGGAGCAGAGTTTCCAGGGC CTGAGTAGCATCCTGAACCTGCCTCAGCCGGAGCTCGCGGAGGAGGCTGCCCAGCGGCAC ACACAGCTCACAGGCCCTGCGCTCGAGGCCTGGACAGACAGGGAACTGAGCAGCTTCTGG TCCGTGGCTGGACTGTGTGCCATAGGCCCCTCTCCCTGCCCCTCCCTGGAGCCCTGCAGA CTGACCAGCTGGAGCTCTCTGTCCCCCGACCCCAAATCAGAGCTGGGGCCTGTCAAAGCA GACGGGCGACTCAGGTAG Clone variation with respect to NM_022167.2 177 g=>a;342 c=>t;914 g=>c;1569 t=>c >OriGene 5' read for NM_022167 unedited
TATAACCCCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG CGAATTCGGCACGAGGGTTGCAGGGCTGGGCGCGCGCCCCGCGTCCCGGGCAGGAAGATG GTGGCGAGCGCGCGAGTGCAGAAGCTGGTGCGGCGCTACAAGCTGGCGATTGCCACGGCG CTGGCCATCCTGCTGCTGCAGGGCCTGGTAGTGTGGAGCTTCAGCGGCCTGGAGGAGGAC GAGGCGGGCGAGAAAGGAAGGCAGAGGAAGCCACGGCCACTGGACCCTGGCGAAGGTTCC AAGGACACAGACAGTTCAGCAGGGCGACGGGGCAGCACAGGCAGAAGGCATGGGCGCTGG CGGGGCCGTGCTGAGAGCCCAGGAGTGCCCGTGGCCAAGGTGGTACGGGCAGTAACCAGC CGGCAGAGAGCCAGCCGGCGGGTCCCACCTGCCCCACCTCCGGAAGCCCCAGGCCGCCAG AACCTGAGTGGGGCAGCAGCTGGGGAGGCGCTGGTAGGGGCAGCTGGCTTCCCACCACAC GGAGATACAGGGAGCGTGGAGGGCGCCCCCCAGCCCACGGACAATGGCTTCACCCCCAAG TGCGAGATCGTGGGCAAGGACGCACTGTCTGCACTGGCCCGGGCCAGCACCAAGCAGTGC CAGCAGGAGATCGCCAATGTGGTGTGCCTGCACCAGGCTGGGAGCCTCATGCCCAAGGCT GTGCCCCGGCACTGTCAGCTGACTGGGAAGATGAGCCCCGGCATCCAGTGGGATGAGAGC CAAGCCCAGCAGCCCATGGATGGCCCCNCGGTGCGAATCGNCTCATGCTGGTGGTTCACG GCCGCGCCATCCGCCAGCTGGAGCGTCTNCTCAAGGCCT >OriGene 3' read for NM_022167 unedited
CGGGGAAATACTATGTACGCGGCCGCTTTCTANGATCGATTTTTTTTTTTTTTTTTTAGA GGAGAAGAGATATATTTCTTCTGTTGCATATTTCAGACTTCACGCTGAGCTTCAGGCACA ATTACTCCAGGTTCTTCTGAGAGTCTTGACAGAGTCTTCTTCCCACGCTGCTCATGTGAC CTCACTTCCAGTGCACACCTGGAAACTCTGCATGGGTCTCATTGGGCCCTGACCCTGCCT TTCCCATCCAGGGGCAGGGTATGCTGGAAAGCCCTGGAGCCGCCCCACCCCACTTCTAGG GTCCCCTGGCTACAAAAGAACTGTCCTGCTAGAGCCCAGCTCTGCAGCGCCCCCGATATC ACCTGTTCTTCGGGCCTTAGAGCCTGGCAGGGCACTTGCAGCCCTGTGGAGCCTCAGCCA CGAGCACCACAGGCCCAGAATGGGGCATGAGGCCCTGGAGAGTGAGGCAAGCCCAGCCTC GTGCAGAACAATAGCAGGTGGGCTCAACAAGCCCCTGCTCCCCACAGACATGGCCCACTT CCTGGGGCTGCTCTGAGCCCTATTGCACATCTTCTGGTCTAGTTTCTCTCCCAACCACCC ATTTTCCTTTTTAAATTTAAAACAAAAAAAGAAAAAGAAAAAAAAGAAATTCCCACTATA CCGGAAGGTGAAGAAGAACTGGGGGTGGAATGCTGCTGTGCCCCTTTTGGGTTTCCGCCA GCCCTCTGGATCCCCACAAAAAACTCAGCAGTAGTTTATAATGGGGCCACCTTTCCTGGC CCCTGTGTGGGGTTCTTGAAGGGTCAAAAGGGGGGGCAACCCTGGGCCCCTGGTTTCTTG CCCGGTGGGAGAGGAGAACCCCTCCCCTGGGTTGA |
Restriction Sites | NotI-NotI |
ACCN | NM_022167 |
Insert Size | 3700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_022167.1, NP_071450.1 |
RefSeq Size | 3568 bp |
RefSeq ORF | 2598 bp |
Locus ID | 64132 |
UniProt ID | Q9H1B5 |
Domains | Branch |
Protein Families | Transmembrane |
Protein Pathways | Chondroitin sulfate biosynthesis, Heparan sulfate biosynthesis, Metabolic pathways |
Gene Summary | The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] Transcript Variant: This variant (1) represents the protein-coding transcript. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
---|
Human Xylosyltransferase II Is Involved in the Biosynthesis of the Uniform Tetrasaccharide Linkage Region in Chondroitin Sulfate and Heparan Sulfate Proteoglycans
,Claudia Ponighaus, Michael Ambrosius, Javier Carrera Casanova, Christian Prante, Joachim Kuhn, Jeffrey D. Esko, Knut Kleesiek, Christian Gotting,
J Biol Chem. 2007 Feb 23;282(8):5201-6.
[XYLT2]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208572 | XYLT2 (Myc-DDK-tagged)-Human xylosyltransferase II (XYLT2) |
CNY 6,336.00 |
|
RC208572L1 | Lenti ORF clone of Human xylosyltransferase II (XYLT2), Myc-DDK-tagged |
CNY 8,736.00 |
|
RC208572L2 | Lenti ORF clone of Human xylosyltransferase II (XYLT2), mGFP tagged |
CNY 5,890.00 |
|
RC208572L3 | Lenti ORF clone of Human xylosyltransferase II (XYLT2), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC208572L4 | Lenti ORF clone of Human xylosyltransferase II (XYLT2), mGFP tagged |
CNY 8,736.00 |
|
RG208572 | XYLT2 (tGFP-tagged) - Human xylosyltransferase II (XYLT2) |
CNY 7,936.00 |