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TLR5 (NM_003268) Human Untagged Clone
CAT＃: SC112789
TLR5 (untagged)-Human toll-like receptor 5 (TLR5)
CNY 6,288.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MELIOS; SLE1; SLEB1; TIL3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003268 edited
CCTATAGTCTCAGGAACTGAAGTCTTTAAACAACCAGGGACCCTCTGCCCCTAGAATAAG AACATACTAGAAGTCCCTTCTGCTAGGACAACGAGGATCATGGGAGACCACCTGGACCTT CTCCTAGGAGTGGTGCTCATGGCCGGTCCTGTGTTTGGAATTCCTTCCTGCTCCTTTGAT GGCCGAATAGCCTTTTATCGTTTCTGCAACCTCACCCAGGTCCCCCAGGTCCTCAACACC ACTGAGAGGCTCCTGCTGAGCTTCAACTATATCAGGACAGTCACTGCTTCATCCTTCCCC TTTCTGGAACAGCTGCAGCTGCTGGAGCTCGGGAGCCAGTATACCCCCTTGACTATTGAC AAGGAGGCCTTCAGAAACCTGCCCAACCTTAGAATCTTGGACCTGGGAAGTAGTAAGATA TACTTCTTGCATCCAGATGCTTTTCAGGGACTGTTCCATCTGTTTGAACTTAGACTGTAT TTCTGTGGTCTCTCTGATGCTGTATTGAAAGATGGTTATTTCAGAAATTTAAAGGCTTTA ACTCGCTTGGATCTATCCAAAAATCAGATTCGTAGCCTTTACCTTCATCCTTCATTTGGG AAGTTGAATTCCTTAAAGTCCATAGATTTTTCCTCCAACCAAATATTCCTTGTATGTGAA CATGAGCTCGAGCCCCTACAAGGGAAAACGCTCTCCTTTTTTAGCCTCGCAGCTAATAGC TTGTATAGCAGAGTCTCAGTGGACTGGGGAAAATGTATGAACCCATTCAGAAACATGGTG CTGGAGATACTAGATGTTTCTGGAAATGGCTGGACAGTGGACATCACAGGAAACTTTAGC AATGCCATCAGCAAAAGCCAGGCCTTCTCTTTGATTCTTGCCCACCACATCATGGGTGCC GGGTTTGGCTTCCATAACATCAAAGATCCTGACCAGAACACATTTGCTGGCCTGGCCAGA AGTTCAGTGAGACACCTGGATCTTTCACATGGGTTTGTCTTCTCCCTGAACTCACGAGTC TTTGAGACACTCAAGGATTTGAAGGTTCTGAACCTTGCCTACAACAAGATAAATAAGATT GCAGATGAAGCATTTTACGGACTTGACAACCTCCAAGTTCTCAATTTGTCATATAACCTT CTGGGGGAACTTTACAGTTCGAATTTCTATGGACTACCTAAGGTAGCCTACATTGATTTG CAAAAGAATCACATTGCAATAATTCAAGACCAAACATTCAAATTCCTGGAAAAATTACAG ACCTTGGATCTCCGAGACAATGCTCTTACAACCATTCATTTTATTCCAAGCATACCCGAT ATCTTCTTGAGTGGCAATAAACTAGTGACTTTGCCAAAGATCAACCTTACAGCGAACCTC ATCCACTTATCAGAAAACAGGCTAGAAAATCTAGATATTCTCTACTTTCTCCTACGGGTA CCTCATCTCCAGATTCTCATTTTAAATCAAAATCGCTTCTCCTCCTGTAGTGGAGATCAA ACCCCTTCAGAGAATCCCAGCTTAGAACAGCTTTTCCTTGGAGAAAATATGTTGCAACTT GCCTGGGAAACTGAGCTCTGTTGGGATGTTTTTGAGGGACTTTCTCATCTTCAAGTTCTG TATTTGAATCATAACTATCTTAATTCCCTTCCACCAGGAGTATTTAGCCATCTGACTGCA TTAAGGGGACTAAGCCTCAACTCCAACAGGCTGACAGTTCTTTCTCACAATGATTTACCT GCTAATTTAGAGATCCTGGACATATCCAGGAACCAGCTCCTAGCTCCTAATCCTGATGTA TTTGTATCACTTAGTGTCTTGGATATAACTCATAACAAGTTCATTTGTGAATGTGAACTT AGCACTTTTATCAATTGGCTTAATCACACCAATGTCACTATAGCTGGGCCTCCTGCAGAC ATATATTGTGTGTACCCTGACTCGCTCTCTGGGGTTTCCCTCTTCTCTCTTTCCACGGAA GGTTGTGATGAAGAGGAAGTCTTAAAGTCCCTAAAGTTCTCCCTTTTCATTGTATGCACT GTCACTCTGACTCTGTTCCTCATGACCATCCTCACAGTCACAAAGTTCCGGGGCTTCTGT TTTATCTGTTATAAGACAGCCCAGAGACTGGTGTTCAAGGACCATCCCCAGGGCACAGAA CCTGATATGTACAAATATGATGCCTATTTGTGCTTCAGCAGCAAAGACTTCACATGGGTG CAGAATGCTTTGCTCAAACACCTGGACACTCAATACAGTGACCAAAACAGATTCAACCTG TGCTTTGAAGAAAGAGACTTTGTCCCAGGAGAAAACCGCATTGCCAATATCCAGGATGCC ATCTGGAACAGTAGAAAGATCGTTTGTCTTGTGAGCAGACACTTCCTTAGAGATGGCTGG TGCCTTGAAGCCTTCAGTTATGCCCAGGGCAGGTGCTTATCTGACCTTAACAGTGCTCTC ATCATGGTGGTGGTTGGGTCCTTGTCCCAGTACCAGTTGATGAAACATCAATCCATCAGA GGCTTTGTACAGAAACAGCAGTATTTGAGGTGGCCTGAGGATCTCCAGGATGTTGGCTGG TTTCTTCATAAACTCTCTCAACAGATACTAAAGAAAGAAAAAGAAAAGAAGAAAGACAAT AACATTCCGTTGCAAACTGTAGCAACCATCTCCTAATCAAAGGAGCAATTTCCAACTTAT CTCAAGCCACAAATAACTCTTCACTTTGTATTTGCACCAAGTTATCATTTTGGGGTCCTC TCTGGAGGTTTTTTTT >OriGene 5' read for NM_003268 unedited
GGATTTTGGTATACGACTCACTATAGGGCGGCCCGCGAATCGGCACGAGGCCCAGAGTCT CACTCTGCCGCCCAGGCTGGACTGCAGTGACACAATCTCGGCTGACTGCAACCACTGCCT CCAGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGATTGATG TTCATGTTCCTGACACTACTACAAGATTCATACTCCTGATGCTACTGACAACGTGGCTTC TCCACAGTCACCAAACCAGGGATGCTATACTGGACTTCCCTACTCTCATCTGCTCCAGCC CCCTGACCTTATAGTTGCCCAGCTTTCCTGGCAATTGACTTTGCCCATCAATACACAGGA TTTAGCATCCAGGGAAGATGTCGGAGCCTCAGATGTTAATTTTCTAATTGAGAATGTTGG CGCTGTCCGAACCTGGAGACAGAGTATCAGCGCCTTTGCTTGCTGCTGTTTTTGCTGTTT TTTGATGCTGGGAACCACCACCTAAAGATAGTAAAGAAAACACAGGAAGCTTTCCGGAAA ACAAAAAGTCCTTTCTCCTGATTCACCAAAAAATAAAATACTGACTACCATCACTGTGAT GAGATTCCTATAGTCTCAGGAACTGAAGTCTTTAAACAACCAGGGACCCTCTGCCCCTAG AATAAGAACATACTAGAAGTCCCTTCTGCTAGGACAACGAGGATCATGGGAGACCACCTG GACCTTCTCCTAGGAGTGGTGCTCATGGCCGGTCCTGTGTTTGGGATTCCTTCCTGCTCC TTTGATGGCCGAATAGCCTTNTATCGNTTCTGNCACCTCNACCCAGTCCCNCCAGTCCTC ACACCACTGAGAGGCTCCTGCTGAGCTTCACTATATCCAGACAGTCACTGCTTCATCCTT CCCTTTTCTGNACAGCTGCAGCTGCTGGAGCTCGGNAGCCATATACCCCCTTGACTATGC ACAGGNNAGGCTN >OriGene 3' read for NM_003268 unedited
GCCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGGCAGTTGCAATTTTCT AGATCTATTATTTTCCATTTGGAGGTTAGTGAGACAGAACATGGTGTTGATACGAAAATT GAGAGATTTATGTTGTTTTCATAGTAGCAAAAAGAAAAAAAAAACCTCCAGAGAGGACCC CAAAATGATAACTTGGTGCAAATACAAAGTGAAGAGTTATTTGTGGCTTGAGATAAGTTG GAAATTGCTCCTTTGATTAGGAGATGGTTGCTACAGTTTGCAACGGAATGTTATTGGCTT TCTTCTTTTCTTTTTCTTTCTTTAGTATCTGTTGAGAGAGTTTATGAAGAAACCAGCCAA CATCCTGGAGATCCTCAGGCCACCTCAAATACTGCTGTTTCTGTACAAAGCCTCTGATGG ATTGATGTTTCATCAACTGGTACTGGGACAAGGACCCAACCACCACCATGATGAGAGCAC TGTTAAGGTCAGATAAGCACCTGCCCTGGGCATAACTGAAGGCTTCAAGGCACCAGCCAT CTCTAAGGAAGTGTCTGCTCACAAGACAAACGATCTTTCTACTGTTCCAGATGGCATCCT GGATATTGGCAATGCGGTTTTCTCCTGGGACAAAGTCTCTTTCTTCAAAGCACAGGTTGA ATCTGTTTTGGTCACTGTATTGAGTGTCCAGGTGTTTGAGCAAGCATTCTGCACCCATGT GAAGTCTTTGCTGCTNGAGCACAATAGGCATCATATTTGTACTATCANGGNTCTGTGCCC TGGGGATGGTCTTTGACACCAGTCTCTGGGCTGTCTTATACAAATAAACAGAGCCCCGGG ACTTTGTGACTGTGAGGATGGTCATGAGGAACAGAGTCANATGACAGTGCATACATGAAA AGGAGAACTTTAGACTTTAAGACTTCTCTCATACAACCTTCGGGAAAGAGAAAAGGAACC CCNAGGCGGTCGGGTCCCCAATATGTTGGAGGAGCCCCCTTATGACATGGGGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003268 |
| Insert Size | 3600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003268.3, NP_003259.2 |
| RefSeq Size | 3369 bp |
| RefSeq ORF | 2577 bp |
| Locus ID | 7100 |
| UniProt ID | O60602 |
| Domains | TIR, LRRCT, LRR, LRR_TYP, LRR_SD22, LRR_PS |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway |
| Gene Summary | This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215293 | TLR5 (Myc-DDK-tagged)-Human toll-like receptor 5 (TLR5) |
CNY 6,288.00 |
|
| RC215293L1 | Lenti ORF clone of Human toll-like receptor 5 (TLR5), Myc-DDK-tagged |
CNY 8,688.00 |
|
| RC215293L2 | Lenti ORF clone of Human toll-like receptor 5 (TLR5), mGFP tagged |
CNY 5,890.00 |
|
| RC215293L3 | Lenti ORF clone of Human toll-like receptor 5 (TLR5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215293L4 | Lenti ORF clone of Human toll-like receptor 5 (TLR5), mGFP tagged |
CNY 8,688.00 |
|
| RG215293 | TLR5 (tGFP-tagged) - Human toll-like receptor 5 (TLR5) |
CNY 7,888.00 |
