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CD40L (CD40LG) (NM_000074) Human Untagged Clone
CAT＃: SC112886
CD40LG (untagged)-Human CD40 ligand (CD40LG)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 2,600.00
CNY 3,600.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD40L; CD154; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000074 edited
ATGATCGAAACATACAACCAAACTTCTCCCCGATCTGCGGCCACTGGACTGCCCATCAGC ATGAAAATTTTTATGTATTTACTTACTGTTTTTCTTATCACCCAGATGATTGGGTCAGCA CTTTTTGCTGTGTATCTTCATAGAAGGTTGGACAAGATAGAAGATGAAAGGAATCTTCAT GAAGATTTTGTATTCATGAAAATGATACAGAGATGCAACACAGGAGAAAGATCCTTATCC TTACTGAACTGTGAGGAGATTAAAAGCCAGTTTGAAGGCTTTGTGAAGGATATAATGTTA AACAAAGAGGAGACGAAGAAAGAAAACAGCTTTGAAATGCAAAAAGGTGATCAGAATCCT CAAATTGCGGCACATGTCATAAGTGAGGCCAGCAGTAAAACAACATCTGTGTTACAGTGG GCTGAAAAAGGATACTACACCATGAGCAACAACTTGGTAACCCTGGAAAATGGGAAACAG CTGACCGTTAAAAGACAAGGACTCTATTATATCTATGCCCAAGTCACCTTCTGTTCCAAT CGGGAAGCTTCGAGTCAAGCTCCATTTATAGCCAGCCTCTGCCTAAAGTCCCCCGGTAGA TTCGAGAGAATCTTACTCAGAGCTGCAAATACCCACAGTTCCGCCAAACCTTGCGGGCAA CAATCCATTCACTTGGGAGGAGTATTTGAATTGCAACCAGGTGCTTCGGTGTTTGTCAAT GTGACTGATCCAAGCCAAGTGAGCCATGGCACTGGCTTCACGTCCTTTGGCTTACTCAAA CTCTGA >OriGene 5' read for NM_000074 unedited
NGGGTGCGCATTTGTATACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGTAACGTT TTTGCTGGGAGAGAAGACTACGAAGCACATTTTCCAGGAAGTGTGGGCTGCAACGATTGT GCGCTCTTAACTAATCCTGAGTAAGGTGGCCACTTTGACAGTCTTCTCATGCTGCCTCTG CCACCTTCTCTGCCAGAAGATACCATTTCAACTTTAACACAGCATGATCGAAACATACAA CCAAACTTCTCCCCGATCTGCGGCCACTGGACTGCCCATCAGCATGAAAATTTTTATGTA TTTACTTACTGTTTTTCTTATCACCCAGATGATTGGGTCAGCACTTTTTGCTGTGTATCT TCATAGAAGGTTGGACAAGATAGAAGATGAAAGGAATCTTCATGAAGATTTTGTATTCAT GAAAATGATACAGAGATGCAACACAGGAGAAAGATCCTTATCCTTACTGAACTGTGAGGA GATTAAAAGCCAGTTTGAAGGCTTTGTGAAGGATATAATGTTAAACAAAGAGGAGACGAA GAAAGAAAACAGCTTTGAAATGCAAAAAGGTGATCAGAATCCTCAAATTGCGGCACATGT CATAAGTGAGGCCAGCAGTAAAACAACATCTGTGTTACAGTGGGCTGAAAAAGGATACTA CACCATGAGCAACAACTTGGTAACCCTGGAAAATGGGAAACAGCTGACCGTTAANAGACA GGGACTCTATTATATCTATGCCCAAGTCACCTTCTGTTCCAAATCGGAAGCTTCGAGTCA AGCTCCATTTATAGCCAGCCTCTGCCTAAAGTCCCCCGGTAGATTCGAGAGAAATCTACT CAGAGCTGCAAATACCCACAGTTNCGCCAAACCTTTGCGGNNCACATNCATTC >OriGene 3' read for NM_000074 unedited
CGGCACGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTAATGTTAAAAGGTCTTTA TTATTCAAAAAATAAATAACAAGATAATTACAAGTTCACTCTGGAAACAATGGAGACTGC AGGTAGATACAATAGATTTCCTTTAAATACAGTCATTTCGTAATGAGGAGTGGGCAGGCT CAGGGCTGCACTCCCTACTCCTCACCCTCATCTATAGTGGTAGAGATAGGGACAGGGTGG AAAGAAGAGAACTGACTAGCAACGGCCTGACTCTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAAGGGGGATTGAGAAGAGAGACTGGG GGAGGGAAGAGACTGACAAAGGGAAACAGAGAGATTGAGAAAGAGAGATTGGAAGAAAGA GGTTGAGAGAGAGAGACTGAAAGAGAGAGATGGAGAGAGAGAGATTGAAAGAGAATGAAT AACTGTCCGAGAGGGTGGCGGGGGGGGGGGGGTTTCGGTTCTCCACTGTGTTAGACGTTC TAGAGCCTGGCCCCCTCCAACAAGGCCATAGGAACCCAGAGTCAACCATAACTGAATGTG AGCTGAGGCTCCCCATTTCCCTTCTGCATCTTCACTGATAAATCAAATGCATTATCCATG GAAAGACACTGCACGCAAAGAAACAAAACTGAACTTGGCAAGTTATCTGCTGTTTACTCA GAATTCAACCTGTGCATAATGGCCCTGTCTTTTCATAGGACTCTCTGGAAGTCTGCATCA GAGGGGTTGCTGCTTCAAAATATAACCCTTTAGGAGCAAGGCCCGTTTTGCTTCATGTGA CCTGTAATCCATTTATTACGGTTCACATGCCCTGGAAAGGATAATAAATAGTCCTCCATA AGGAGGACCCAGGGTTATAAAAAGCAGTTAACGGGGGGGGGCCTAACCCTCGGGCTCGTT TAAAGAAACCCCACGCCAACTCTCACCCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000074 |
| Insert Size | 2070 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000074.2, NP_000065.1 |
| RefSeq Size | 1834 bp |
| RefSeq ORF | 786 bp |
| Locus ID | 959 |
| UniProt ID | P29965 |
| Domains | TNF |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Viral myocarditis |
| Gene Summary | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes
,Xin M. Luo, Emily Maarschalk, Ryan M. O'Connell, Pin Wang, Lili Yang, and David Baltimore,
Blood, Feb 2009; 113: 1422 - 1431.
[CD40LG]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210004 | CD40LG (Myc-DDK-tagged)-Human CD40 ligand (CD40LG) |
CNY 2,400.00 |
|
| RC210004L1 | Lenti ORF clone of Human CD40 ligand (CD40LG), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210004L2 | Lenti ORF clone of Human CD40 ligand (CD40LG), mGFP tagged |
CNY 5,890.00 |
|
| RC210004L3 | Lenti ORF clone of Human CD40 ligand (CD40LG), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210004L4 | Lenti ORF clone of Human CD40 ligand (CD40LG), mGFP tagged |
CNY 5,890.00 |
|
| RG210004 | CD40LG (tGFP-tagged) - Human CD40 ligand (CD40LG) |
CNY 4,000.00 |
|
| SC338162 | CD40LG (untagged)-Human CD40 ligand (CD40LG) |
CNY 2,850.00 |
