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ADAM28 (NM_021777) Human Untagged Clone
CAT＃: SC112924
ADAM28 (untagged)-Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3
CNY 6,040.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAM 28; eMDC II; eMDCII; MDC-L; MDCL |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112924 sequence for NM_021777 edited (data generated by NextGen Sequencing)
ATGTTGCAAGGTCTCCTGCCAGTCAGTCTCCTCCTCTCTGTTGCAGTAAGTGCTATAAAA GAACTCCCTGGGGTGAAGAAGTATGAAGTGGTTTATCCTATAAGACTTCATCCACTGCAT AAAAGAGAGGCCAAAGAGCCAGAGCAACAGGAACAATTTGAAACTGAATTAAAGTATAAA ATGACAATTAATGGAAAAATTGCAGTGCTTTATTTGAAAAAAAACAAGAACCTCCTTGCA CCAGGCTACACGGAAACATATTATAATTCCACTGGAAAGGAGATCACCACAAGCCCACAA ATTATGGATGATTGTTATTATCAAGGACATATTCTTAATGAAAAGGTTTCTGACGCTAGC ATCAGCACATGTAGGGGTCTAAGGGGCTACTTCAGTCAGGGGGATCAAAGATACTTTATT GAACCTTTAAGCCCCATACATCGGGATGGACAGGAGCATGCACTCTTCAAGTATAACCCT GATGAAAAGAATTATGACAGCACCTGTGGGATGGATGGTGTGTTGTGGGCCCACGATTTG CAGCAGAACATTGCCCTACCTGCCACCAAACTAGTAAAATTGAAAGACAGGAAGGTTCAG GAACATGAGAAATACATAGAATATTATTTGGTCCTGGATAATGGTGAGTTTAAAAGGTAC AATGAGAATCAAGATGAGATCAGAAAGAGGGTATTTGAGATGGCTAATTATGTCAACATG CTTTATAAAAAGCTCAATACTCATGTGGCCTTAGTTGGTATGGAAATCTGGACTGACAAG GATAAGATAAAGATAACCCCAAATGCAAGCTTCACCTTGGAGAATTTTTCTAAATGGAGG GGGAGTGTTCTCTCAAGAAGAAAGCGTCATGATATTGCTCAGTTAATCACAGCAACAGAA CTTGCTGGAACGACTGTGGGTCTTGCATTTATGTCTACAATGTGTTCTCCTTATTCTGTT GGCGTTGTTCAGGACCACAGCGATAATCTTCTTAGAGTTGCAGGGACAATGGCACATGAA ATGGGCCACAACTTTGGAATGTTTCATGACGACTATTCTTGCAAGTGTCCTTCTACAATA TGTGTGATGGACAAAGCACTGAGCTTCTATATACCCACAGACTTCAGTTCCTGCAGCCGT CTCAGCTATGACAAGTTTTTTGAAGATAAATTATCAAATTGCCTCTTTAATGCTCCATTG CCTACAGATATCATATCCACTCCAATTTGTGGGAACCAGTTGGTGGAAATGGGAGAGGAC TGTGATTGTGGGACATCTGAGGAATGTACCAATATTTGCTGTGATGCTAAGACATGTAAA ATCAAAGCAACTTTTCAATGTGCATTAGGAGAATGTTGTGAAAAATGCCAATTTAAAAAG GCTGGGATGGTGTGCAGACCAGCAAAAGATGAGTGCGACCTGCCTGAAATGTGTAATGGT AAATCTGGTAATTGTCCTGATGATAGATTCCAAGTCAATGGCTTCCCTTGCCATCACGGG AAGGGCCACTGCTTGATGGGGACATGCCCCACACTGCAGGAGCAGTGCACAGAGCTGTGG GGACCAGGTAGGAGGACAAATCCTTTCCCCTGTGCATGTGCGAAGGAAAATCATTTCAGA TGA Clone variation with respect to NM_021777.3 >OriGene 5' read for NM_021777 unedited
TGTTANATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCCACCTGAG CGAGAAGAGCAGACACCGTGCTCCTGGAATCACCCAGCATGTTGCAAGGTCTCCTGCCAG TCAGTCTCCTCCTCTCTGTTGCAGTAAGTGCTATAAAAGAACTCCCTGGGGTGAAGAAGT ATGAAGTGGTTTATCCTATAAGACTTCATCCACTGCATAAAAGAGAGGCCAAAGAGCCAG AGCAACAGGAACAATTTGAAACTGAATTAAAGTATAAAATGACAATTAATGGAAAAATTG CAGTGCTTTATTTGAAAAAAAACAAGAACCTCCTTGCACCAGGCTACACGGAAACATATT ATAATTCCACTGGAAAGGAGATCACCACAAGCCCACAAATTATGGATGATTGTTATTATC AAGGACATATTCTTAATGAAAAGGTTTCTGACGCTAGCATCAGCACATGTAGGGGTCTAA GGGGCTACTTCAGTCAGGGGGATCAAAGATACTTTATTGAACCTTTAAGCCCCATACATC GGGATGGACAGGAGCATGCACTCTTCAAGTATAACCCTGATGAAAAGAATTATGACAGCA CCTGTGGGATGGATGGTGTGTTGTGGGCCCACGATTTGCAGCAGAACATTGCCCTACCTG CCACCAAACTAGTAAAATTGAAAGACAGGAAGGTTCAGGAACATGAGAAATACATAGAAT ATTATTTGGTCCTGGATAATGGTGAGTTTAAAAGGTACAATGAGAATCAAGATGAGATCA GANAGAGGGTATTTGAGATGGCTAATTATGTCAACATGCTNNTATAAAAGCTCAATACTC ATGTGGCCCTAGTTGGTATGGAAATCTGGNACTGACAGGGATAGATAAGATAACCCAAAT GCAGCTTCACCTTGGAGAATTTTCTA >OriGene 3' read for NM_021777 unedited
TTGCTATGCCACGCGGCACGCATTCTAAGATCGGTTTTTTTTTTTTTTTTTTCTTTTTTT TTTTTTTTTTTTGGAGACGGAGTCTGGCTTTGTCACCCAGGCTGGAGTGCAGTGGCACGA TCTCTGCTGACGGCAAGCTCCGCCTCCTGGGTTCAGGCCCTTCTCCTGCCTCAGCCTCCC GAGTAGCTGGGACAGGCGCCCACTAGCACGCCCGGCTAATTTTTTGGATTTTTAGTAGAG ACGGGGTTTCACCGTGTTAGCCAGGATGGGCTTGATCTCCTGACCTCGTGATCCGCCCGC CTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCTGGCCAAAGTTATT TAATACTATACAAATTGCTGTTTAAATTTTCGGATATCTCTTTAAACTTTTATTTTTCAA GTTTTCTTGGTGAAATTAGAGAATATGGTCTCTAAAATTTTGGCATTATGGACAAAGCGA CCATTTAAGAACTTTCACTTTTCTTTATTGGCTTTCTGCATTTCCAGAGTTCTTTTCTTT TTTCCATCTTTTCTTATTTCTGGCCCATCCCACAGTACTTCTGCCACCCCTGCACACACA CACACACACACACACCCGGACACACACAGATTTCCAAGGGTTTATGATCTTAATAGGGTT GCCAGATGAAAAGAAAAAGACACCCCAGTTTAATTTGAATTTCAGAAACACAAATAATTT TAGTATGAGCACACCTCATATATTGCATGGGATATACTGATGCTGAGACAAAAACATAAA TTACAAAAACTTGTAATTTTAGTTAAAATTAACGGGCCATCCTTATTTTACTGCTAAACT AGCACCCTAAACCACCTCAACCTAAACCTTCCATGATTGAATCGAGCTCTAGAAGATAGA CGATGGCCTTGACTGGTAACATGCATCTGAAGATTTCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021777 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021777.2, NP_068547.2 |
| RefSeq Size | 2076 bp |
| RefSeq ORF | 1623 bp |
| Locus ID | 10863 |
| UniProt ID | Q9UKQ2 |
| Domains | Reprolysin, DISIN, Pep_M12B_propep, ACR |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (3, also known as MDC-Ls) lacks several exons and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 3 which is shorter and has a distinct C-terminus, compared to isoform 1. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217827 | ADAM28 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3 |
CNY 6,032.00 |
|
| RC217827L1 | Lenti ORF clone of Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, Myc-DDK-tagged |
CNY 6,650.00 |
|
| RC217827L2 | Lenti ORF clone of Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, mGFP tagged |
CNY 6,650.00 |
|
| RC217827L3 | Lenti ORF clone of Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, Myc-DDK-tagged |
CNY 6,650.00 |
|
| RC217827L4 | Lenti ORF clone of Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, mGFP tagged |
CNY 6,650.00 |
|
| RG217827 | ADAM28 (tGFP-tagged) - Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3 |
CNY 7,632.00 |
