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DR6 (TNFRSF21) (NM_014452) Human Untagged Clone
CAT＃: SC114967
TNFRSF21 (untagged)-Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21)
CNY 7,328.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BM-018; CD358; DR6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114967 sequence for NM_014452 edited (data generated by NextGen Sequencing)
ATGGGGACCTCTCCGAGCAGCAGCACCGCCCTCGCCTCCTGCAGCCGCATCGCCCGCCGA GCCACAGCCACGATGATCGCGGGCTCCCTTCTCCTGCTTGGATTCCTTAGCACCACCACA GCTCAGCCAGAACAGAAGGCCTCGAATCTCATTGGCACATACCGCCATGTTGACCGTGCC ACCGGCCAGGTGCTAACCTGTGACAAGTGTCCAGCAGGAACCTATGTCTCTGAGCATTGT ACCAACACAAGCCTGCGCGTCTGCAGCAGTTGCCCTGTGGGGACCTTTACCAGGCATGAG AATGGCATAGAGAAATGCCATGACTGTAGTCAGCCATGCCCATGGCCAATGATTGAGAAA TTACCTTGTGCTGCCTTGACTGACCGAGAATGCACTTGCCCACCTGGCATGTTCCAGTCT AACGCTACCTGTGCCCCCCATACGGTGTGTCCTGTGGGTTGGGGTGTGCGGAAGAAAGGG ACAGAGACTGAGGATGTGCGGTGTAAGCAGTGTGCTCGGGGTACCTTCTCAGATGTGCCT TCTAGTGTGATGAAATGCAAAGCATACACAGACTGTCTGAGTCAGAACCTGGTGGTGATC AAGCCGGGGACCAAGGAGACAGACAACGTCTGTGGCACACTCCCGTCCTTCTCCAGCTCC ACCTCACCTTCCCCTGGCACAGCCATCTTTCCACGCCCTGAGCACATGGAAACCCATGAA GTCCCTTCCTCCACTTATGTTCCCAAAGGCATGAACTCAACAGAATCCAACTCTTCTGCC TCTGTTAGACCAAAGGTACTGAGTAGCATCCAGGAAGGGACAGTCCCTGACAACACAAGC TCAGCAAGGGGGAAGGAAGACGTGAACAAGACCCTCCCAAACCTTCAGGTAGTCAACCAC CAGCAAGGCCCCCACCACAGACACATCCTGAAGCTGCTGCCGTCCATGGAGGCCACTGGG GGCGAGAAGTCCAGCACGCCCATCAAGGGCCCCAAGAGGGGACATCCTAGACAGAACCTA CACAAGCATTTTGACATCAATGAGCATTTGCCCTGGATGATTGTGCTTTTCCTGCTGCTG GTGCTTGTGGTGATTGTGGTGTGCAGTATCCGGAAAAGCTCGAGGACTCTGAAAAAGGGG CCCCGGCAGGATCCCAGTGCCATTGTGGAAAAGGCAGGGCTGAAGAAATCCATGACTCCA ACCCAGAACCGGGAGAAATGGATCTACTACTGCAATGGCCATGGTATCGATATCCTGAAG CTTGTAGCAGCCCAAGTGGGAAGCCAGTGGAAAGATATCTATCAGTTTCTTTGCAATGCC AGTGAGAGGGAGGTTGCTGCTTTCTCCAATGGGTACACAGCCGACCACGAGCGGGCCTAC GCAGCTCTGCAGCACTGGACCATCCGGGGCCCCGAGGCCAGCCTCGCCCAGCTAATTAGC GCCCTGCGCCAGCACCGGAGAAACGATGTTGTGGAGAAGATTCGTGGGCTGATGGAAGAC ACCACCCAGCTGGAAACTGACAAACTAGCTCTCCCGATGAGCCCCAGCCCGCTTAGCCCG AGCCCCATCCCCAGCCCCAACGCGAAACTTGAGAATTCCGCTCTCCTGACGGTGGAGCCT TCCCCACAGGACAAGAACAAGGGCTTCTTCGTGGATGAGTCGGAGCCCCTTCTCCGCTGT GACTCTACATCCAGCGGCTCCTCCGCGCTGAGCAGGAACGGTTCCTTTATTACCAAAGAA AAGAAGGACACAGTGTTGCGGCAGGTACGCCTGGACCCCTGTGACTTGCAGCCTATCTTT GATGACATGCTCCACTTTCTAAATCCTGAGGAGCTGCGGGTGATTGAAGAGATTCCCCAG GCTGAGGACAAACTAGACCGGCTATTCGAAATTATTGGAGTCAAGAGCCAGGAAGCCAGC CAGACCCTCCTGGACTCTGTTTATAGCCATCTTCCTGACCTGCTGTAG Clone variation with respect to NM_014452.3 >OriGene 5' read for NM_014452 unedited
GTTCACATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGCCGGGAGGC GGCGGTGGATGCGGCGCTGGGCAGAAGCAGCCGCCGATTCCAGCTGCCCCGCGCGCCCCG GGCGCCCCTGCGAGTCCCCGGTTCAGCCATGGGGACCTCTCCGAGCAGCAGCACCGCCCT CGCCTCCTGCAGCCGCATCGCCCGCCGAGCCACAGCCACGATGATCGCGGGCTCCCTTCT CCTGCTTGGATTCCTTAGCACCACCACAGCTCAGCCAGAACAGAAGGCCTCGAATCTCAT TGGCACATACCGCCATGTTGACCGTGCCACCGGCCAGGTGCTAACCTGTGACAAGTGTCC AGCAGGAACCTATGTCTCTGAGCATTGTACCAACACAAGCCTGCGCGTCTGCAGCAGTTG CCCTGTGGGGACCTTTACCAGGCATGAGAATGGCATAGAGAAATGCCATGACTGTAGTCA GCCATGCCCATGGCCAATGATTGAGAAATTACCTTGTGCTGCCTTGACTGACCGAGAATG CACTTGCCCACCTGGCATGTTCCAGTCTAACGCTACCTGTGCCCCCCATACGGTGTGTCC TGTGGGTTGGGGTGTGCGGAAGAAAGGGACAGAGACTGAGGATGTGCGGTGTAAGCAGTG TGCTCGGGGTACCTTCTCAGATGTGCCTTCTAGTGTGATGAAATGCAAAGCATACACAGA CTGTCTGAGTCAGAACCTGGTGGTGATCAAGCCGGGGNACCAAGGAGACAGGACACGTCT GTGGCACACTCCCGTCCTTCTCCAGCTCCACCTCACCTTTCCCTGGCACAGCCATCTTTT CACGCCCTGAGCACATGGGAACCCATTGAGTCCCTTCCTCCACTTATGGTCCCAAAGGCA TGAACTCAACAGAATCCAACTT >OriGene 3' read for NM_014452 unedited
GGCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT AACAAACACCTAATGTTTATTAATAAATTAGTACACTTGAAGGCATTTTTCTGATATCGG TCCTTCACCACTACCCACAAACCCCACCCACACAAAGGGAGTCCACGCCACCTTTGCATT GGAACCTGGCAACTGAGCATTAAAAGGTACATTTGTAAATGGGAGCATAGTTGCAAATAT ATCAAACAAGGGTTCTTACAGTTGCAGCCATTTTTAATTAAAGTAATTGGGGAAGGAATC CCACCAGGACCAAGGCCTTGAAAGCAAATTGGACCTATTGATTATGTGTATATAAAAAAC AAAACATCTTTTAAAGCAAAGCTGGGCAAATTCTCTATGGAAAGGGCGCCACTGGCACTT GATTTTGACTTTCCAAAGTGCAGCAATGTGTTCCAAAACAGCTCAAATCCTAAAAGGGGA AGTTCAAGTTCTTTGGTGGCCCAGTTGTCAAGCCACTTAAATAGCAAATCCTGATGGCTT GAGGATTTCATTTCTCCAGCCCAGAGCATATTAGCATAAGAAGAGTACAAGTAATCAAGC ATTCTACACGGTGTCCAGGTGAAAACCATACAATCAGCAATAGTGTGGTCAAGTTTCAGC CATGAATATGAACTATACAAGACATATTTAAAAGATAACTCAAAGTTGAATTGCATTACA GTAACTCAATGGGGTCTTAAATTTTCTTAATCTTTAAGACAATTTTAAAGGACAAACAAT AATAAAAATAGTACTAATCTTTGGTTTTAAAAAGTANGTGTGAATGTTAAGAGACATAAA GACTGCTTATAGGATTACAAGATGCCTTATACTTTTAAGAGTTAAGACCTCACATCCAGG NGTGGNGAAAGCACACTGCTTTATGTNNAGTAGAAAATTAAAGGCCAGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014452 |
| Insert Size | 3630 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014452.3, NP_055267.1 |
| RefSeq Size | 3662 bp |
| RefSeq ORF | 1968 bp |
| Locus ID | 27242 |
| UniProt ID | O75509 |
| Domains | DEATH, TNFR |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
| Gene Summary | This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205864 | TNFRSF21 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21) |
CNY 7,312.00 |
|
| RC205864L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21), Myc-DDK-tagged |
CNY 9,712.00 |
|
| RC205864L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21), mGFP tagged |
CNY 9,712.00 |
|
| RC205864L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21), Myc-DDK-tagged |
CNY 9,712.00 |
|
| RC205864L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21), mGFP tagged |
CNY 5,890.00 |
|
| RG205864 | TNFRSF21 (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 21 (TNFRSF21) |
CNY 8,912.00 |
