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MKRN1 (NM_013446) Human Untagged Clone
CAT＃: SC115218
MKRN1 (untagged)-Human makorin ring finger protein 1 (MKRN1), transcript variant 1
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RNF61 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_013446 edited
GAATTCGGCACGAGGGTAATGGCGGAGGCTGCAACTCCCGGAACAACAGCCACAACATCA GGAGCAGGAGCGGCAGCGGCGACGGCGGCAGCAGCCTCCCCCACCCCGATCCCCACAGTC ACCGCCCCGTCCCTGGGGGCGGGCGGAGGGGGCGGCGGCAGCGACGGCAGCGGCGGCGGC TGGACTAAACAGGTCACCTGCAGGTATTTTATGCATGGGGTTTGTAAGGAAGGAGACAAC TGTCGCTACTCGCATGACCTCTCTGACAGTCCGTATAGTGTAGTGTGCAAGTATTTTCAG CGAGGGTACTGTATTTATGGAGACCGCTGCAGATATGAACATAGCAAACCATTGAAACAG GAAGAAGCAACTGCTACAGAGCTAACTACAAAGTCATCCCTTGCTGCTTCCTCAAGTCTC TCATCGATAGTTGGACCACTTGTTGAAATGAATACAGGCGAAGCTGAGTCAAGAAATTCA AACTTTGCAACTGTAGGAGCAGGTTCAGAGGACTGGGTGAATGCTATTGAGTTTGTTCCT GGGCAACCCTACTGTGGCCGTACTGCGCCTTCCTGCACTGAAGCACCCCTGCAGGGCTCA GTGACCAAGGAAGAATCAGAGAAAGAGCAAACCGCCGTGGAGACAAAGAAGCAGCTGTGC CCCTATGCTGCAGTGGGAGAGTGCCGATACGGGGAGAACTGTGTGTATCTCCACGGAGAT TCTTGTGACATGTGTGGGCTGCAGCTCCTGCATCCAATGGATGCTGCCCAGAGATCGCAG CATATCAAATCGTGCATTGAGGCCCATGAGAAGGACATGGAGCTCTCATTTGCCGTGCAG CGCAGCAAGGACATGGTGTGTGGGATCTGCATGGAGGTGGTCTATGAGAAAGCCAACCCC AGTGAGCGCCGCTTCGGGATCCTCTCCAACTGCAACCACACCTACTGTCTCAAGTGCATT CGCAAGTGGAGGAGTGCTAAGCAATTTGAGAGCAAGATCATAAAGTCCTGCCCAGAATGC CGGATCACATCTAACTTTGTCATTCCAAGTGAGTACTGGGTGGAGGAGAAAGAAGAGAAG CAGAAACTCATTCTGAAATACAAGGAGGCAATGAGCAACAAGGCGTGCAGGTATTTTGAT GAAGGACGTGGGAGCTGCCCATTTGGAGGGAACTGTTTTTACAAGCATGCGTACCCTGAT GGCCGTAGAGAGGAGCCACAGAGACAGAAAGTGGGAACATCAAGCAGATACCGGGCCCAA CGAAGGAACCACTTCTGGGAACTCATTGAGGAAAGAGAGAACAGCAACCCCTTTGACAAC GATGAAGAAGAGGTTGTCACCTTTGAGCTGGGCGAGATGTTGCTTATGCTTTTGGCTGCA GGTGGGGACGACGAACTAACAGACTCTGAAGATGAGTGGGACTTGTTTCATGATGAGCTG GAAGATTTTTATGACTTGGATCTATAGCAACCTTGCGTGGCGTGTGAACTGGTCTGCTGA CCTCAGACAGCAGCTGTCCCCTGTGGTGGTGTGGCAGTGCCTGTGTTCTCTCCTAGGCAG GCCTCTCAACTCCAGGTGCTGTCCTAAGAATTTTTACCCAGGGCCTGTCTTCTCAACCCC TCACCTTTCCCTGAGGAGTGTGTTGTTTTCCCTGTTGAAAAAAGTTACAAAAATAAATCT TAAAGTTAGTTTTTTGTAACACGAATTTAACTGTCAGACAGTTAGTGTAGGTGTGTTGCG TCATCTGTTTTCAACCAGATTGCATTTATGGACTTTTCACACACTCATTTTGAGGACCCC AGGTTCAAAAGTAAAAGCAGTGGCCCTGCTTTGGGGTCCAAGAATAGGAGTGATGGGTGA AGGGACCTAAGCTGGCCAATAGCCCTCTGCCCCAGACATGGGATGTGGATCCTTGAGGTT TCTGGTGAAATCTGCACATCTGTGTTTTTATATCTGTTCCCTACCCTGTAATCCCTACCA CGTGCACTTGTTCTGTGGTTTTGGTCTCTTGTTTAATTGCACACAAGTAATACTACTGGG TAACCAGAATCAGGTGTGAATGTGTTGAGATTTTTTACTGTTTTGCATGATAGGAAAATT GAGAAAGAATACGTATAAAAGATAGAGAGGCATAACATCAATGCAGAGTTGGAAGTTGGC TCCCAAGGGCTGACATGGTGTGAGTGTGTGGGTGTGTGATAAGCTTCTCATCCCTGCATA GATGCAGTATTCTTAGCCTTAGTAGAAAAACCTGGTTTAGTGGTTTAAGCCTTGTGTGGC AGATAGATCTTAAAGGGCAAAGCAGTATATTGGTAGTTGTCAATATAGCAGTGCTAGCTC TGTCTATATAAATAGAGAAATGGGGTTAGCCATAGAGGTTAAAACTACCTGGTTATCCCA TATAATAACACAAACTGGGTCTTGGATACACAGTTGTATTTAATGTTTTACGATCTAGCC TTTCCAGTACAGGCACTTTCTGAGAAACCTTTGTCCTCACTTGAGGCATTTTGTTGTCGG GTTTTTGTGTTTGTTTTTGTGGGTATTTGCCTCATTCCACCCCTGAGCTTTCAGGTAGAC AGACGTGATTCAAAACTCTGTTCTAAGGTGTTTATTGTAGTGGAGTAATGGGTTTGCAGT GATAAGTCATACTTTTCCACCGAAAGGGAGGGCTTGGGAATCCCTGAGATTAGCTAAAGT TAAGTTGTTGGAAGAATTCCTTGATTGGAAATTGTACCTTTGTGTTTTGTTGCTCTGTTT CCTGAAAATAACTCGGGGATGCTCCTGGTTTGTCCATCTACTGCTTTGATTCCTTGGATC CCACCCATTCTTTCACTTTAAGAAAAAACAAATAATTGTTGCAGAGGTCTCTGTATTTTG CAGCTGCCCTTTTGTAAGAAGCACTTTTCCCAAATAAAACAATTAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_013446 unedited
GGGTTTAAATTTGTAAACGACTCATATAGGCGGCCCGCGAATCGGCAGGAGGGTAATGGC GGAGGCTGCAACTCCCGGNACAACAGCCACAACATCAGGAGCAGGAGCGGCAGCGGCGAC GGCGGCAGCAGCCTCCCCCACCCCGATCCCCACAGTCACCGCCCCGTCCCTGGGGGCGGG CGGAGGGGGCGGCGGCAGCGACGGCAGCGGCGGCGGCTGGACTAAACAGGTCACCTGCAG GTATTTTATGCATGGGGTTTGTAAGGAAGGAGACAACTGTCGCTACTCGCATGACCTCTC TGACAGTCCGTATAGTGTAGTGTGCAAGTATTTTCAGCGAGGGTACTGTATTTATGGAGA CCGCTGCAGATATGAACATAGCAAACCATTGAAACAGGAAGAAGCAACTGCTACAGAGCT AACTACAAAGTCATCCCTTGCTGCTTCCTCAAGTCTCTCATCGATAGTTGGACCACTTGT TGAAATGAATACAGGCGAAGCCTGAGTCAAGAAATTCAAACTTTGCAACTGTAGGAGCAG GTTCAGAGGACTGGGTGAATGCCTATTGAGTTTGTTCCTGTGCAACCCTACTGTGGCCGT ACTGCGCCTTCCTGCACTGAAGCACCCCTGCAGGGCCTCACTGACCACAGGAAGAATCAG AGAAAGAGCAAACCCGCCGCTGGAGACCAAAGAACCAGCTGTGCCCCCTCATGCTGCAGT GGGGAGAGTGCCCGATACCCGGGAGAACTGTGTGCATCTCCACGGCAGATTCTTGTGAAC ATGTGTGGGGCTGCAGGTCCTGCATTCCAAGGGATGCTGCCCCAAAGACCGCAGCATCAT CAAATCCTGCATTGAAGCCCCATGAGAAAGACATGAAGCCCTCATTTGCCCGGGCACAGC ACCAAGCACAGGGA >OriGene 3' read for NM_013446 unedited
CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTAATCGTTTTATTTGGGAAAAAGTGCTTCTTACAAAAGGGCAGCTGCAAAATACAAA AACCTCTGCAACAATTATTTGTTTTTTCTTAAAGGGAAAAAATGGGTGGGATCCAAGGAA TCAAAGCAGTAGATGGACAAACCAGGAGCCTCCCCGAGTTATTTTCAGGAAACAGACCAA CAAAACACAAAGGTCCAATTCCCAATCAAGGAATTCTTCCAACAACTTAACTTTATCTAA TCTCAGGGATTCCCAACCCCTCCCTTTCGGTGGAAAAGTATGACTTATCACTGCAAACCC ATTACTCCACTACAATAAACACCTTAAAACAAAGCTTTGAATCACGTCTGTCTACCTGAA CGCCTAGGGGCGGCATGAGGCAAATCCCCACCAAACCAAACACAAAAACCCCACCACAAA ATGCCTTAAGCGAGGACAAAGGTTTCCCAAAAAGTGCCTGTCCTGCAAAGGCCTACACCC CAAAACCTTAAACACAACTGGGTTTTCAAAACCCCATTTGTGCTATCATATGGGACAACC CAGTCACTCTAACCTTTATGGTTCACCCCCATTTGTCTCTTTCCTATAAACAAACCTACC TACTGTCTATTTGCAAATTAACAACCTACTGGCTCGCCCTTTAAAATCCTCCTGCCACAC AGGCTTAACTTCTTACACCGTCCTTTTTCTAAGGCCAAAATCTGCCTCCTCTCGGGATGA AAACTTACTAACACCCCCCATTTCTCCTTGCCCTCCTTGGAGACACTTCCACTTTCATTG CGCCCTGCCCCTTCCCTTTACCCCTTCTTTTCCCTCTCCTTCGCACAAACTTAAATTGTA CTTTCCCCCCGTTTGGCCCCCCCCCTTACTTGCGCCCCCAACCTAACCCCCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_013446 |
| Insert Size | 3070 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013446.2, NP_038474.1 |
| RefSeq Size | 3116 bp |
| RefSeq ORF | 1449 bp |
| Locus ID | 23608 |
| UniProt ID | Q9UHC7 |
| Domains | zf-CCCH, RING |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206848 | MKRN1 (Myc-DDK-tagged)-Human makorin ring finger protein 1 (MKRN1), transcript variant 1 |
CNY 3,656.00 |
|
| RC206848L1 | Lenti ORF clone of Human makorin ring finger protein 1 (MKRN1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC206848L2 | Lenti ORF clone of Human makorin ring finger protein 1 (MKRN1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206848L3 | Lenti ORF clone of Human makorin ring finger protein 1 (MKRN1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206848L4 | Lenti ORF clone of Human makorin ring finger protein 1 (MKRN1), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG206848 | MKRN1 (tGFP-tagged) - Human makorin ring finger protein 1 (MKRN1), transcript variant 1 |
CNY 5,256.00 |
