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XRN2 (NM_012255) Human Untagged Clone
CAT＃: SC115463
XRN2 (untagged)-Human 5'-3' exoribonuclease 2 (XRN2)
CNY 10,448.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_012255, the custom clone sequence may differ by one or more nucleotides
ATGGGAGTCCCGGCGTTCTTCCGCTGGCTCAGCCGCAAGTACCCGTCCATCATAGTCAACTGCGTGGAAG AGAAGCCAAAAGAATGCAATGGTGTAAAGATTCCAGTTGATGCCAGTAAACCTAATCCAAATGATGTGGA GTTTGATAATCTGTATTTGGATATGAATGGAATCATCCATCCCTGTACTCATCCTGAAGACAAACCAGCA CCAAAAAATGAAGATGAAATGATGGTTGCAATTTTTGAGTACATTGACAGACTTTTCAGTATTGTAAGAC CAAGAAGACTTCTCTACATGGCAATAGATGGAGTGGCACCACGTGCTAAAATGAACCAGCAGCGTTCAAG GAGGTTCAGGGCATCAAAAGAAGGAATGGAAGCAGCAGTCGAGAAGCAGCGAGTCAGGGAAGAAATATTG GCAAAAGGTGGCTTTCTTCCTCCAGAAGAAATAAAAGAAAGATTTGACAGCAACTGTATTACACCAGGAA CTGAATTCATGGACAATCTTGCTAAATGCCTTCGCTATTACATAGCTGATCGTTTAAATAATGACCCTGG GTGGAAAAATTTGACAGTTATTTTATCTGATGCTAGTGCTCCTGGTGAAGGAGAACATAAAATCATGGAT TACATTAGAAGGCAAAGAGCCCAGCCTAACCATGACCCAAATACTCATCATTGTTTATGTGGAGCAGATG CTGATCTCATTATGCTTGGCCTTGCCACACATGAACCGAACTTTACCATTATTAGAGAAGAATTCAAACC AAACAAGCCCAAACCATGTGGTCTTTGTAATCAGTTTGGACATGAGGTCAAAGATTGTGAAGGTTTGCCA AGAGAAAAGAAGGGAAAGCATGATGAACTTGCCGATAGTCTTCCTTGTGCAGAAGGAGAGTTTATCTTCC TTCGGCTTAATGTTCTTCGTGAGTATTTGGAAAGAGAACTCACAATGGCCAGCCTACCATTCACATTTGA TGTTGAGAGGAGCATTGATGACTGGGTTTTCATGTGCTTCTTTGTGGGAAATGACTTCCTCCCTCATTTG CCATCGTTAGAGATTAGGGAAAATGCAATTGACCGTTTGGTTAACATATACAAAAATGTGGTACACAAAA CTGGGGGTTACCTTACAGAAAGTGGTTATGTCAATCTGCAAAGAGTACAGATGATCATGTTAGCAGTTGG TGAAGTTGAGGATAGCATTTTTAAAAAGAGAAAGGATGATGAGGACAGTTTTAGAAGACGACAGAAAGAA AAAAGAAAGAGAATGAAGAGAGATCAACCAGCTTTCACTCCTAGTGGAATATTAACTCCTCATGCCTTGG GTTCAAGAAATTCACCAGGTTCTCAAGTAGCCAGTAATCCGAGACAAGCAGCCTATGAAATGAGGATGCA GAATAACTCTAGTCCTTCGATATCTCCTAATACGAGTTTCACATCTGATGGCTCCCCGTCTCCATTAGGA GGAATTAAGCGAAAAGCAGAAGACAGTGACAGTGAACCTGAGCCAGAGGATAATGTCAGGTTATGGGAAG CTGGCTGGAAGCAGCGGTACTACAAGAACAAATTTGATGTGGATGCAGCTGATGAGAAATTCCGTCGGAA AGTTGTGCAGTCGTACGTTGAAGGACTTTGCTGGGTTCTTAGATATTATTACCAGGGCTGTGCTTCCTGG AAGTGGTATTATCCATTTCATTATGCACCATTTGCTTCAGACTTTGAAGGCATTGCAGACATGCCATCTG ATTTTGAGAAGGGTACGAAACCGTTTAAACCACTAGAACAACTTATGGGGGTATTTCCAGCTGCAAGTGG TAATTTTCTACCTCCATCATGGCGGAAGCTCATGAGTGATCCTGATTCTAGTATAATTGACTTCTATCCT GAAGATTTTGCTATTGATTTGAATGGGAAGAAATATGCATGGCAAGGTGTTGCTCTCTTGCCATTCGTGG ATGAGCGAAGGCTACGAGCTGCCCTAGAAGAGGTATACCCAGACCTCACTCCAGAAGAGACCAGAAGAAA CAGCCTTGGAGGTGATGTCTTATTTGTGGGGAAACATCACCCACTCCATGACTTCATTTTAGAGCTGTAC CAGACAGGTTCCACAGAGCCAGTGGAGGTACCCCCTGAACTATGTCATGGGATTCAAGGAAAGTTTTCTT TGGATGAAGAAGCCATTCTTCCAGATCAAATAGTATGTTCTCCTGTTCCTATGTTAAGGGATCTGACACA GAACACTGTAGTCAGTATTAATTTTAAAGACCCACAGTTTGCTGAAGATTACATTTTTAAAGCTGTAATG CTTCCAGGAGCAAGAAAGCCAGCAGCAGTACTGAAACCTAGTGACTGGGAAAAATCCAGCAATGGACGGC AGTGGAAGCCTCAGCTTGGCTTTAACCGTGACCGGAGGCCTGTGCACCTGGATCAGGCAGCCTTCAGGAC TTTGGGCCATGTGATGCCAAGAGGCTCAGGAACTGGCATTTACAGCAATGCTGCACCACCACCTGTGACT TACCAGGGAAACTTATACAGGCCGCTTTTGAGAGGACAAGCCCAGATTCCAAAACTTATGTCAAATATGA GGCCCCAGGATTCCTGGCGAGGTCCTCCTCCCCTTTTCCAGCAGCAAAGGTTTGACAGAGGCGTTGGGGC TGAACCTCTGCTCCCATGGAACCGGATGCTGCAAACCCAGAATGCAGCCTTCCAGCCAAACCAGTACCAG ATGCTAGCTGGGCCTGGTGGGTATCCACCCAGACGAGATGATCGTGGAGGGAGACAGGGATATCCCAGAG AAGGAAGGAAATACCCTTTGCCACCACCCTCAGGAAGATACAATTGGAATTAA >OriGene 5' read for NM_012255 unedited
CACAGCAATTCGCACGAGGGTCAGCCGGTCGGCCGCCGCCTCCAGCCGTGTGCCGCTATG GGAGTCCCGGCGTTCTTCCGCTGGCTCAGCCGCAAGTACCCGTCCATCATAGTCAACTGC GTGGAAGAGAAGCCAAAAGAATGCAATGGTGTAAAGATTCCAGTTGATGCCAGTAAACCT ATTCCAAATGATGTGGAGTTTGATAATCTGTATTTGGATATGAATGGAATCATCCATCCC TGTACTCATCCTGAAGACAAACCAGCACCAAAAAATGAAGATGAAATGATGGTTGCAATT TTTGAGTACATTGACAGACTTTTCAGTATTGTAAGACCAAGAAGACTTCTCTACATGGCA ATAGATGGAGTGGCACCACGTGCTAAAATGAACCAGCAGCGTTCAAGGAGGTTCAGGGCA TCAAAAGAAGGAATGGAAGCAGCAGTCGAGAAGCAGCGAGTCAGGGAAGAAATATTGGCA AAAGGTGGCTTTCTTCCTCCAGAAGAAATAAAAGAAAGATTTGACAGCAACTGTATTACA CCAGGAACTGAATTCATGGACAATCTTGCTAAATGCCTTCGCTATTACATAGCTGATCGT TTAAATAATGACCCTGGGTGGAAAAATTTGACAGTTATTTTATCTGATGCTAGTGCTCCT GGTGAAGGAGAACATAAAATCATGGATTACATTAGAAGGCANAGAGCCCAGCCTAACCAT GACCCANATACTCATCATTGTTTATGTGGAGCAGATGCTGATCTCATTATGCTTGGGCCT GCCACACATGAACCGAACTTTACCATTATTAGAGAAGAATTCANACCANNACAGCCCAAA CCATGTGGGTCTTTGTAATCAGTTTGGACATGANGTCAAAGATGA >OriGene 3' read for NM_012255 unedited
GACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGAGTTTTAAAAGTTTA ACTTTATTTTTTTTTACTAAAGTTCAGAAATTTCTGTAAGACAAGTACATTAATGAAATG TTTCCAAAGAAATACTGAACAATATATACTCTAGTTTGCTGAGGTTCCAGCTCAAGAGTT CAAACCTAATTCTTGTGCAATAAAAATCAGCATGGATCTTAGATGATCTAGAATACACTG TGTTTTGAAATCCACAGCTGGTTTCATTTTTAACCATTATGAAAAACCAGTACTCCTATT CCATCAAATGTGTTTTATAAGCAATAATAAATTCAGATCCACTGTATTATGCAACATACA TCTTTGGAAAGCAACATAAACAGTGAGATCAGATCAGTAGAAATATACACAGTTAAAAGA AATACACAAAGTACTGTAGTTTTATTAAAAACTACTACTTGAGAAAGAAATCTTTCCACA AATAGCATAAAACTGTAGAATGATGAAAGGATTTGGGAAAGCTTTACAAAAGCTTAATTC CAATTGTATCTTCCTGAGGGTGGTGGCAAAGGGTATTTCCTTCCTTCTCTGGGATATCCC TGTCTCCCTCCACGATCATCTCGTCTGGGTGGATACCCACCAGGCCCAGCTAGCATCTGG TACTGGTTTGGCTGGAAGGCTGCATTCTGGGTTTGCAGCATCCGGTTCCATGGGAGCAGA GGTNCAGCCCCAACGCCTCTGTCAAACCTTTGCTGCTGGAAAGGGGAGGAGGACCTCGCC AGGAATCCTGGGGCCTATATTTGACATAAGTTTGGATCTGGGCTTGTCTCTCAAAACGCC TGTTTAAGTTCCCTGGTAGTCACAGGGGGGGTGCAGCATGCTGTAAATGCATTCCTGACC CTTTGGCTCCCATGCCCAAATCCTGAAGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012255 |
| Insert Size | 3570 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012255.3, NP_036387.2 |
| RefSeq Size | 3449 bp |
| RefSeq ORF | 2853 bp |
| Locus ID | 22803 |
| UniProt ID | Q9H0D6 |
| Domains | DUF251 |
| Protein Pathways | RNA degradation |
| Gene Summary | This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (2) contains an alternate 5' terminal exon, resulting in a distinct 5' UTR and the use of an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus , and is shorter, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223980 | XRN2 (Myc-DDK-tagged)-Human 5'-3' exoribonuclease 2 (XRN2) |
CNY 10,432.00 |
|
| RC223980L3 | Lenti ORF clone of Human 5'-3' exoribonuclease 2 (XRN2), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC223980L4 | Lenti ORF clone of Human 5'-3' exoribonuclease 2 (XRN2), mGFP tagged |
CNY 12,832.00 |
|
| RG223980 | XRN2 (tGFP-tagged) - Human 5'-3' exoribonuclease 2 (XRN2) |
CNY 7,890.00 |
