HP1 gamma (CBX3) (NM_007276) Human Untagged Clone

CAT#: SC115632

CBX3 (untagged)-Human chromobox homolog 3 (CBX3), transcript variant 1



  "NM_007276" in other vectors (6)

CNY 3,600.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
HP1 gamma/CBX3 Rabbit polyclonal Antibody
    • 100 ul

CNY 2,900.00

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TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms HECH; HP1-GAMMA; HP1Hs-gamma
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_007276, the custom clone sequence may differ by one or more nucleotides


ATGGCCTCCAACAAAACTACATTGCAAAAAATGGGAAAAAAACAGAATGGAAAGAGTAAAAAAGTTGAAG
AGGCAGAGCCTGAAGAATTTGTCGTGGAAAAAGTACTAGATCGACGTGTAGTGAATGGGAAAGTGGAATA
TTTCCTGAAGTGGAAGGGATTTACAGATGCTGACAATACTTGGGAACCTGAAGAAAATTTAGATTGTCCA
GAATTGATTGAAGCGTTTCTTAACTCTCAGAAAGCTGGCAAAGAAAAAGATGGTACAAAAAGAAAATCTT
TATCTGACAGTGAATCTGATGACAGCAAATCAAAGAAGAAAAGAGATGCTGCTGACAAACCAAGAGGATT
TGCCAGAGGTCTTGATCCTGAAAGAATAATTGGTGCCACAGACAGCAGTGGAGAATTGATGTTTCTCATG
AAATGGAAAGATTCAGATGAGGCAGACTTGGTGCTGGCGAAAGAGGCAAATATGAAGTGTCCTCAAATTG
TAATTGCTTTTTATGAAGAGAGACTAACTTGGCATTCTTGTCCAGAAGATGAAGCTCAATAA


>OriGene 5' read for NM_007276 unedited
GTGTCACCTTTTGTATACGACTCACTATAGGCGGCCGCGAATCGCACGAGGGCGGAGGGC
CGGAGACGCTGCAGACCCGCGACCCGGAGCAGCTCGGAGGCGGTGAATAATAGCTCTTCA
AGTCTGCAATAAAAAAGGCCTCCAACAAAACTACATTGCAAAAAATGGGAAAAAAACAGA
ATGGAAAGAGTAAAAAAGTTGAAGAGGCAGAGCCTGAAGAATTTGTCGTGGAAAAAGTAC
TAGATCGACGTGTAGTGAATGGGAAAGTGGAATATTTCCTGAAGTGGAAGGGATTTACAG
ATGCTGACAATACTTGGGAACCTGAAGAAAATTTAGATTGTCCAGAATTGATTGAAGCGT
TTCTTAACTCTCAGAAAGCTGGCAAAGAAAAAGATGGTACAAAAAGAAAATCTTTATCTG
ACAGTGAATCTGATGACAGCAAATCAAAGAAGAAAAGAGATGCTGCTGACAAACCAAGAG
GATTTGCCAGAGGTCTTGATCCTGAAAGAATAATTGGTGCCACAGACAGCAGTGGAGAAT
TGATGTTTCTCATGAAATGGAAAGATTCAGATGAGGCAGACTTGGTGCTGGCGAAAGAGG
CAAATATGAAGTGTCCTCAAATTGTAATTGCTTTTTATGAAGAGAGACTAACTTGGCATT
CTTGTCCAGAAGATGAAGCTCAATAATTGNTCACATTGNTCTTTTATATATATTTATATA
TATATATATAAAAATTGCGTCTTAGATTTTGATTTACTAGTGTGACAAATAACTACATNC
CTATGAAAATCAAGTTTGATATGTTTGTTTTGAAAGTANCGCTGNAAAGATTGTNTGGGG
TTTTTTTGCATCCATAGCACTGGTTACTTTGAACCAATAAATAAAGCCTTCTGTAGNTGC
TCCCTTCATCG
>OriGene 3' read for NM_007276 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCATAAAGGAATATAA
AACTATTTATTAACCACTGTTCACCAGTATTTACAATAAAGTAAACAATATACAGTTGGA
TAACATTTTGATTACTACAAAGTTGTTCTTCCTGGCTTTTGCTGAACCAGTAAAGCAAAC
TCAAGATTGAGCCTCCATGTAATGAATTGGGGTAAAGAAAAAACATGCAGGTCAATAGGT
TAGGTTACAAAAGGTTGTTCACACATTTATGACAGCAGGTCCTAAACTGCCAACACCTCT
AACCATCTGATTAGGTTTCTATGAGCCAAGTCTTACATATTCCATTCATCATGACCTTTT
AGTCAATGTAGCAACAGGGATTCCAACATTTTGCTAAGGAATGGCCCGCTAGGGAAACTT
TTAAATGTTCATTTAACTTAGTTTTGTTTAGCTAGTTAAAACACACTAGCATTTGTCTAG
TTTCCTCATCTGGATGAGGAAACCTGCTGTGATGGCAGTGATAAAATTTTTCCTTTTAGG
AATTTTGCAAATAAACCACTGCAATTATAGACACTTTAAAATTATCCAATTTAAATTGTC
CTATCTAGAATTACTTATTTCACTTGAAATGTATGGTTTCAGGAAAATTTTCAATTTAAC
TTGAAGGGATTATCTCTTATTTTGCTTGGAATAATGGCATCTCAGAAACATGGGTTTACC
TGTGATTTTTTTGTTTGGGTGAATGCTTAAAAACAAAAAAAATTACATATGCATTTTATG
GATACACACACACACACACACACACACACACACACAAAAACACGTAATAAATCTAGAATG
GTCCTTTAGCTCATGAGAACACCAGTTTGACTGAGTATGACTATGGACTTTTCCCCAAAT
TAAAAAAGCT
Restriction Sites NotI-NotI     
ACCN NM_007276
Insert Size 1910 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_007276.3, NP_009207.2
RefSeq Size 1837 bp
RefSeq ORF 552 bp
Locus ID 11335
UniProt ID Q13185
Domains CHROMO
Protein Families Druggable Genome, Transcription Factors
Gene Summary At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
Transcript Variant: This variant (1) contains an alternate 5' exon but encodes the same protein as transcript variant 2.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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