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NPR2L (NPRL2) (NM_006545) Human Untagged Clone
CAT＃: SC116029
NPRL2 (untagged)-Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FFEVF2; NPR2; NPR2L; TUSC4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_006545, the custom clone sequence may differ by one or more nucleotides
ATGGGCAGCGGCTGCCGCATCGAATGCATATTCTTCAGCGAGTTCCACCCCACGCTGGGACCCAAGATCA CCTATCAGGTCCCTGAAGACTTCATCTCCCGAGAGCTGTTTGACACAGTCCAAGTGTACATCATCACCAA GCCAGAGCTGCAGAACAAGCTTATCACTGTCACAGCTATGGAAAAGAAGCTGATCGGCTGTCCTGTGTGC ATCGAACACAAGAAGTACAGCCGCAATGCTCTCCTCTTCAACCTGGGCTTCGTGTGTGATGCCCAGGCCA AGACCTGCGCCCTCGAGCCCATTGTTAAAAAGCTGGCTGGCTATCTGACCACACTAGAGCTAGAGAGCAG CTTCGTGTCCATGGAGGAGAGCAAGCAGAAGTTGGTGCCCATCATGACCATCTTGCTGGAGGAGCTAAAT GCCTCAGGCCGGTGCACTCTGCCCATTGATGAGTCCAACACCATCCACTTGAAGGTGATTGAGCAGCGGC CAGACCCTCCGGTGGCCCAGGAGTATGATGTACCTGTCTTTACCAAAGACAAGGAGGATTTCTTCAACTC ACAGTGGGACCTCACTACACAACAAATCCTGCCCTACATTGATGGGTTCCGCCACATCCAGAAGATTTCA GCAGAGGCAGATGTGGAGCTCAACCTGGTGCGCATTGCTATCCAGAACCTGCTGTACTACGGCGTTGTGA CACTGGTGTCCATCCTCCAGTACTCCAATGTATACTGCCCAACGCCCAAGGTCCAGGACCTGGTAGATGA CAAGTCCCTGCAAGAGGCATGTCTATCCTACGTGACCAAGCAAGGGCACAAGAGGGCCAGTCTCCGGGAT GTGTTCCAGCTATACTGCAGCCTGAGCCCTGGCACTACCGTGCGAGACCTCATTGGCCGCCACCCCCAGC AGCTGCAGCATGTTGATGAACGGAAGCTGATCCAGTTCGGGCTTATGAAGAACCTCATCAGGCGACTACA GAAGTATCCTGTGCGGGTGACTCGGGAAGAGCAGAGCCACCCTGCCCGGCTTTATACAGGCTGCCACAGC TATGACGAGATCTGCTGCAAGACAGGCATGAGCTACCATGAGCTGGATGAGCGGCTTGAAAATGACCCCA ACATCATCATCTGCTGGAAGTGA >OriGene 5' read for NM_006545 unedited
CGTCACATTTGTAACACGACTCATATAGGCGGCCGCGAAATTCGCACGAGCCCAGTCCCT GAAGATTCATCTCCCGAGAGCTGGGGAGGGGAGTGGCAATGGGCCCCTCAGTGGACATCT GTACTGGGTGTAGTACAAATGGTGACCTCCTCATGCCCCCCAAGCCCAAGTCCTCTTCCC AGGTCCCTGAAGACTTCATCTCCCGAGAGCTGTTTGACACAGTCCAAGTGTACATCATCA CCAAGCCAGAGCTGCAGAACAAGCTTATCACTGTCTATGGAAAAGAAGCTGATCGGCTGT CCTGTGTGCATCGAACACAAGAAGTACAGCCGCAATGCTCTCCTCTTCAACCTGGGCTTC GTGTGTGATGCCCAGGCCAAGACCTGCGCCCTCGAGCCCATTGTTAAAAAGCTGGCTGGC TATCTGACCACACTAGAGGTCTGCAATGAGATGGGCTTGGGTTTACCGACAGGCAGAGTT GGGGAAGGTGTTCCCATGTCTCCAAAGTCCCCCAAACCTGGGACCCTGCAAACCAGCTCA GGACTCAGGGCAGCCAACCAGCCAGGGGTCCTGGGATGTGCCCACCATGCTTTCCATGCT CTGTCTAGCTAGAGAGCAGCTTCGTGTCCATGGAGGAGAGCAAGCAGAAGTTGGTGCCCA TCATGACCATCTTGCTGGAGGAGCTAAATGCCTCAGGCCGGTGCACTCTGCCCATTGGTA TGGCCAGCCTCTGCAAGGACAGCACAGGGGTACAGGAGAGATGGGAAAGTGACCCAGCTA GTCAGGTAGAAGGGCCAGACTCATGAACACATTGGTGGGCAGGAAATAGCCATGGGCCTG AGTGCCCATGTCCAGGGTCCACAGCATGATGGACCTGGGACTGGGGGTAGGGGGAA >OriGene 3' read for NM_006545 unedited
CTTCCAGGGCCGGNAAAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCA GGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTT GAAATGGATGTCTTTATTTACAGAACTAAGAGTCAACCTCTAGACAGTATGACAAGCCTC CTAGTAGGAGGGACTACCCACAGCAATGTGTCCATCCAGTCACTACCAGCCTCACTTCCA GCAGATGATGATGTTGGGGTCATTTTCAAGCCGCTCATCCAGCTCATGGTAGCTCATGCC TGTCTTGCAGCAGATCTCGTCATAGCTGTGGCAGCCTGTATAAAGCCGGGCAGGGTGGCT CTGCTCTTCCCGAGTCACCCGCACAGGATACTTCTGTAGTCGCCTGATGAGGTTCTTCAT AAGCCCGAACTGGATCAGCTTCCTAGGGTGAGGATCAGAGGACGGGGTGACGCCCTGGCC AGGCCTTCTTTCAGGCAGGCCAACCCTTTCCTGTAGTCTCCCTTCAATTTTGTCTCTGTA GCCCATCATCTCCAGGAAGCCTGGCTTGGATTGGCAGTGCCCCATGATCCAGGGCTCCTG AGAACATAAAGGGTCTAGCTTCCCTCAGGTAACTCCCAAATGCCCCAGCAAATTCTCCTC TGACCGTTATCAACATGCTGAACTGCTGGGGGGGTGGGCGGCAAATGAGGTCTCCACGGG TAGTGCCAGGGCTCAGGCTGGATATAGCTGGACACTNCCGGAACTGCCCTCTGGCCTCGG GGGGGGCCAGGGACACTATTATGTGGGCTGGCTCCCCAAAAGGTTTCCCAGACCACCTAC TTGGTTGGCAGGAAGAAAACTGCTCTGAGGGACTGATTTAACAGCTGCCTTGGGGGGGGG GGGTAATTTGGGTTTCAAGGGCCAACACTGGGCCCCAAAGGGGTGTGAAAACACCCCGTT GTGGGACACAAATCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006545 |
| Insert Size | 2620 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006545.4, NP_006536.3 |
| RefSeq Size | 1672 bp |
| RefSeq ORF | 1143 bp |
| Locus ID | 10641 |
| UniProt ID | Q8WTW4 |
| Protein Families | Druggable Genome |
| Gene Summary | As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204818 | NPRL2 (Myc-DDK-tagged)-Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) |
CNY 3,656.00 |
|
| RC204818L3 | Lenti ORF clone of Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204818L4 | Lenti ORF clone of Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2), mGFP tagged |
CNY 5,890.00 |
|
| RG204818 | NPRL2 (tGFP-tagged) - Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) |
CNY 5,256.00 |
|
| SC321098 | NPRL2 (untagged)-Human nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) |
CNY 3,656.00 |
