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PIK3CB (NM_006219) Human Untagged Clone
CAT＃: SC116228
PIK3CB (untagged)-Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB)
CNY 7,456.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | P110BETA; PI3K; PI3KBETA; PIK3C1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_006219 edited
GAATTCGGCACGAGGGGGCTGCTGACTGCGCACTTGGAATAGTAGCAGGCGGCGGCGGCG GAACGCCAGGCAGGGCCCCGTGGTTATGAATGTGCTTCAGTTTCATAATGCCTCCTGCTA TGGCAGACATCCTTGACATCTGGGCGGTGGATTCACAGATAGCATCTGATGGCTCCATAC CTGTGGATTTCCTTTTGCCCACTGGGATTTATATCCAGTTGGAGGTACCTCGGGAAGCTA CCATTTCTTATATTAAGCAGATGTTATGGAAGCAAGTTCACAATTACCCAATGTTCAACC TCCTTATGGATATTGACTCCTATATGTTTGCATGTGTGAATCAGACTGCTGTATATGAGG AGCTTGAAGATGAAACACGAAGACTCTGTGATGTCAGACCTTTTCTTCCAGTTCTCAAAT TAGTGACAAGAAGTTGTGACCCAGGGGAAAAATTAGACTCAAAAATTGGAGTCCTTATAG GAAAAGGTCTGCATGAATTTGATTCCTTGAAGGATCCTGAAGTAAATGAATTTCGAAGAA AAATGCGCAAATTCAGCGAGGAAAAAATCCTGTCACTTGTGGGATTGTCTTGGATGGACT GGCTAAAACAAACATATCCACCAGAGCATGAACCATCCATCCCTGAAAACTTAGAAGATA AACTTTATGGGGGAAAGCTCATCGTAGCTGTTCATTTTGAAAACTGCCAGGACGTGTTTA GCTTTCAAGTGTCTCCTAATATGAATCCTATCAAAGTAAATGAATTGGCAATCCAAAAAC GTTTGACTATTCATGGGAAGGAAGATGAAGTTAGCCCCTATGATTATGTGTTGCAAGTCA GCGGGAGAGTAGAATATGTTTTTGGTGATCATCCACTAATTCAGTTCCAGTATATCCGGA ACTGTGTGATGAACAGAGCCCTGCCCCATTTTATACTTGTGGAATGCTGCAAGATCAAGA AAATGTATGAACAAGAAATGATTGCCATAGAGGCTGCCATAAATCGAAATTCATCTAATC TTCCTCTTCCATTACCACCAAAGAAAACACGAATTATTTCTCATGTTTGGGAAAATAACA ACCCTTTCCAAATTGTCTTGGTTAAGGGAAATAAACTTAACACAGAGGAAACTGTAAAAG TTCATGTCAGGGCTGGTCTTTTTCATGGTACTGAGCTCCTGTGTAAAACCATCGTAAGCT CAGAGGTATCAGGGAAAAATGATCATATTTGGAATGAACCACTGGAATTTGATATTAATA TTTGTGACTTACCAAGAATGGCTCGATTATGTTTTGCTGTTTATGCAGTTTTGGATAAAG TAAAAACGAAGAAATCAACGAAAACTATTAATCCCTCTAAATATCAGACCATCAGGAAAG CTGGAAAAGTGCATTATCCTGTAGCGTGGGTAAATACGATGGTTTTTGACTTTAAAGGAC AATTGAGAACTGGAGACATAATATTACACAGCTGGTCTTCATTTCCTGATGAACTCGAAG AAATGTTGAATCCAATGGGAACTGTTCAAACAAATCCATATACTGAAAATGCAACAGCTT TGCATGTTAAATTTCCAGAGAATAAAAAACAACCTTATTATTACCCTCCCTTCGATAAGA TTATTGAAAAGGCAGCTGAGATTGCAAGCAGTGATAGTGCTAATGTGTCAAGTCGAGGTG GAAAAAAGTTTCTTCCTGTATTGAAAGAAATCTTGGACAGGGATCCCTTGTCTCAACTGT GTGAAAATGAAATGGATCTTATTTGGACTTTGCGACAAGACTGCCGAGAGATTTTCCCAC AATCACTGCCAAAATTACTGCTGTCAATCAAGTGGAATAAACTTGAGGATGTTGCTCAGC TTCAGGCGCTGCTTCAGATTTGGCCTAAACTGCCCCCCCGGGAGGCCCTAGAGCTTCTGG ATTTCAACTATCCAGACCAGTACGTTCGAGAATATGCTGTAGGCTGCCTGCGACAGATGA GTGATGAAGAACTTTCTCAATATCTTTTACAACTGGTGCAAGTGTTAAAATATGAGCCTT TTCTTGATTGTGCCCTCTCTAGATTCCTATTAGAAAGAGCACTTGGTAATCGGAGGATAG GGCAGTTTCTATTTTGGCATCTTAGGTCAGAAGTGCACATTCCTGCTGTCTCAGTACAAT TTGGTGTCATCCTTGAAGCATACTGCCGGGGAAGTGTGGGGCACATGAAAGTGCTTTCTA AGCAGGTTGAAGCACTCAATAAGTTAAAAACTTTAAATAGTTTAATCAAACTGAATGCCG TGAAGTTAAACAGAGCCAAAGGGAAGGAGGCCATGCATACCTGTTTAAAACAGAGTGCTT ACCGGGAAGCCCTCTCTGACCTGCAGTCACCCCTGAACCCATGTGTTATCCTCTCAGAAC TCTATGTTGAAAAGTGCAAATACATGGATTCCAAAATGAAGCCTTTGTGGCTGGTATACA ATAACAAGGTATTTGGTGAGGATTCAGTTGGAGTGATTTTTAAAAATGGTGATGATTTAC GACAGGATATGTTGACACTCCAAATGTTGCGCTTGATGGATTTACTCTGGAAAGAAGCTG GTTTGGATCTTCGGATGTTGCCTTATGGCTGTTTAGCAACAGGAGATCGCTCTGGCCTCA TTGAAGTTGTGAGCACCTCTGAAACAATTGCTGACATTCAGCTGAACAGTAGCAATGTGG CTGCTGCAGCAGCCTTCAACAAAGATGCCCTTCTGAACTGGCTTAAAGAATACAACTCTG GGGATGACCTGGACCGAGCCATTGAGGAATTTACACTGTCCTGTGCTGGCTACTGTGTAG CTTCTTATGTCCTTGGGATTGGTGACAGACATAGTGACAACATCATGGTCAAAAAAACTG GCCAGCTCTTCCACATTGACTTTGGACATATTCTTGGAAATTTCAAATCTAAGTTTGGCA TTAAAAGGGAGCGAGTGCCTTTTATTCTTACCTATGATTTCATCCATGTCATTCAACAAG GAAAAACAGGAAATACAGAAAAGTTTGGCCGGTTCCGCCAGTGTTGTGAGGATGCATATC TGATTTTACGACGGCATGGGAATCTCTTCATCACTCTCTTTGCGCTGATGTTGACTGCAG GGCTTCCTGAACTCACATCAGTCAAAGATATACAGTATCTTAAGGACTCTCTTGCATTAG GGAAGAGTGAAGAAGAAGCACTCAAACAGTTTAAGCAAAAATTTGATGAGGCGCTCAGGG AAAGCTGGACTACTAAAGTGAACTGGATGGCCCACACAGTTCGGAAAGACTACAGATCTT AACGATCAGCCTTCGCTCCTAATGTATTTGTTGGTTTCATTTCATTTTCATTTTGCACTT GCACTAAATTGAACATGACCCTGTTAGAGATGTTATAAAGGGAATGAAATCCTGGAACTC AGAGTTAAATTAAGAACAAGGCATCCCACAGAACCTAATCTGAACAATCCCCGATGATTC CCTCTGCTTTTTGAATGCTTCCAAGACTTATCATGAAAACTGTCAATGGATAATCATTTC CTGCTGACTTTGCACGCCAAGGAATGCTACTAGGGATTGTTTCCGTTTTTGTTTGTTTTT TCTAATATTTGGTACTTCCCAGAATGGTGTAAATACTTCTTTTCAATGTTGTGACCAAGT ATTGTCACTCAGCCAACAACTTTTCCACACCTGGGGGGTTGGTGGCTGTTCTTACTGTCC AAATGAAGCTAAAAAGAAAGGCATCTTTCTTCCCTTTTAAAATTGTGTAAACTGCAAATT ATAATATAATTTGAATTTATGATTATTTTCCAGAAGAAATCTTGTAAACCTGTGGATACT CATTAATTCTTTTGTTAATATTTATTTCCATGATAGCATCATTCCAGCCAGACTTGCTGA AAATCTACTGGTGAGGCAAATATAATATATATAAATATGCTACATATATATTTATAAAAT TTCTAGTGGGAGTTCTATATAAATGTTTCTTTGGTATTCTTCAGCCTGTGATTTAAAGTT TTACAAAAAGCAGAGCTTTTTCCTAAGTTACTTTTCAGTTAGGTAACTGTGTGATCCAGT TCTTCCAGCTGCTTCTATAATGAGGCACATATTAATACAGTTTTTATATGGTATCTATGA AAGAGTTCACTTCATAGAGAATAATACTTGAGCAAATGTATCCAAGAAAGCAAGCAAATG AAAAGAAACCTATTTATGGAATAAACTCCAGATCTGAAATTCAGTATTTTAGAAAAATGC CAGCTCTTCTTACTGTATTTATTAAAACTTGTAATAATGTGATTTTTTTCAAGGATATTA GTTCAAATTGAAATGGTTTCACGCCACACGGAAATCTTTAAGTTATTTGTTGAGGTACCA TATATTTAGGGTGCTAGGGGCAAGTAATGTTAATATGTGCAATAGGAACTACTGGTTTGA ATGTGTAAATGGGTGATCTCTCTGAGTCCTGGCAACATCCAGCAAAACTACTGCTTATTC TCCAAAGAATATTGGGAGCTCTCAATCCTCGGTGATATGGGAAAGAGAACTGAGTATTTG CCCTATGACTGAGCTTTCTATAGGAATTTTATTAAAGAATGTTTAATTTTGTTGTCCTTC TTAATGTTCTCAGTCAAATAAATGAGTGAGCTGXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_006219 unedited
GCACGAGGGGGCTGCTGACTGCGCACTTGGAATAGTAGCAGGCGGCGGCGGCGGAACGCC AGGCAGGGCCCCGTGGTTATGAATGTGCTTCAGTTTCATAATGCCTCCTGCTATGGCAGA CATCCTTGACATCTGGGCGGTGGATTCACAGATAGCATCTGATGGCTCCATACCTGTGGA TTTCCTTTTGCCCACTGGGATTTATATCCAGTTGGAGGTACCTCGGGAAGCTACCATTTC TTATATTAAGCAGATGTTATGGAAGCAAGTTCACAATTACCCAATGTTCAACCTCCTTAT GGATATTGACTCCTATATGTTTGCATGTGTGAATCAGACTGCTGTATATGAGGAGCTTGA AGATGAAACACGAAGACTCTGTGATGTCAGACCTTTTCTTCCAGTTCTCAAATTAGTGAC AAGAAGTTGTGACCCAGGGGAAAAATTAGACTCAAAAATTGGAGTCCTTATAGGAAAAGG TCTGCATGAATTTGATTCCTTGAAGGATCCTGAAGTAAATGAATTTCGAAGAANAATGCG CAAATTCAGCGAGGAAAAAATCCTGTCACTTGTGGGATTGTCTTGGATGGACTGGCTAAA ACAAACATATCCACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006219 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006219.1, NP_006210.1 |
| RefSeq Size | 3213 bp |
| RefSeq ORF | 3213 bp |
| Locus ID | 5291 |
| UniProt ID | P42338 |
| Domains | PI3K_rbd, PI3_PI4_kinase, PI3Ka, PI3K_C2, PI3K_p85B |
| Protein Families | Druggable Genome |
| Protein Pathways | Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Inositol phosphate metabolism, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway |
| Gene Summary | This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (1) represent the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215433 | PIK3CB (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB) |
CNY 7,448.00 |
|
| RC215433L1 | Lenti ORF clone of Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB), Myc-DDK-tagged |
CNY 9,848.00 |
|
| RC215433L2 | Lenti ORF clone of Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB), mGFP tagged |
CNY 10,260.00 |
|
| RC215433L3 | Lenti ORF clone of Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB), Myc-DDK-tagged |
CNY 10,260.00 |
|
| RC215433L4 | Lenti ORF clone of Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB), mGFP tagged |
CNY 9,848.00 |
|
| RG215433 | PIK3CB (tGFP-tagged) - Human phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB) |
CNY 9,220.00 |
