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HMGCS2 (NM_005518) Human Untagged Clone
CAT＃: SC116704
HMGCS2 (untagged)-Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 3,792.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005518 edited
GCGGCCGCGAATTCGGCACGAGGCTGAACTGCTGGGTTTCTGCTTGCTCCTCTGGAGATG CAGCGTCTGTTGACTCCAGTGAAGCGCATTCTGCAACTGACAAGAGCGGTGCAGGAAACC TCCCTCACACCTGCTCGCCTGCTCCCAGTAGCCCACCAAAGGTTTTCTACAGCCTCTGCT GTCCCCCTGGCCAAAACAGATACTTGGCCAAAGGACGTGGGCATCCTGGCCCTGGAGGTC TACTTCCCAGCCCAATATGTGGACCAAACTGACCTGGAGAAGTATAACAATGTGGAAGCA GGAAAGTATACAGTGGGCTTGGGCCAGACCCGTATGGGCTTCTGCTCAGTCCAAGAGGAC ATCAACTCCCTGTGCCTGACGGTGGTGCAACGGCTGATGGAGCGCATACAGCTCCCATGG GACTCTGTGGGCAGGCTGGAAGTAGGCACTGAGACCATCATTGACAAGTCCAAAGCTGTC AAAACAGTGCTCATGGAACTCTTCCAGGATTCAGGCAATACTGATATTGAGGGCATAGAT ACCACCAATGCCTGCTACGGTGGTACTGCCTCCCTCTTCAATGCTGCCAACTGGATGGAG TCCAGTTCCTGGGATGGTCGTTATGCCATGGTGGTCTGTGGAGACATTGCCGTCTATCCC AGTGGTAATGCTCGTCCCACAGGTGGGGCCGGAGCTGTGGCTATGCTGATTGGGCCCAAG GCCCCTCTGGCCCTGGAGCGAGGGCTGAGGGGAACCCATATGGAGAATGTGTATGACTTC TACAAACCAAATTTGGCCTCGGAGTACCCAATAGTGGATGGGAAGCTTTCCATCCAGTGC TACTTGCGGGCCTTGGATCGATGTTACACATCATACCGTAAAAAAATCCAGAATCAGTGG AAGCAAGCTGGCAGCGATCGACCCTTCACCCTTGACGATTTACAGTACATGATCTTTCAT ACACCCTTTTGCAAGATGGTCCAGAAGTCTCTGGCTCGCCTGATGTTCAATGACTTCCTG TCAGCCAGCAGTGACACACAAACCAGCTTATATAAGGGGCTGGAGGCTTTCGGGGGGCTA AAGCTGGAAGACACCTACACCAACAAGGACCTGGATAAAGCACTTCTAAAGGCCTCTCAG GACATGTTCGACAAGAAAACCAAGGCTTCCCTTTACCTCTCCACTCACAATGGGAACATG TACACCTCATCCCTGTACGGGTGCCTGGCCTCGCTTCTGTCCCACCACTCTGCCCAAGAA CTGGCTGGCTCCAGGATTGGTGCCTTCTCTTATGGCTCTGGTTTAGCAGCAAGTTTCTTT TCATTTCGAGTATCCCAGGATGCTGCTCCAGGCTCTCCCCTGGACAAGTTGGTGTCCAGC ACATCAGACCTGCCAAAACGCCTAGCCTCCCGAAAGTGTGTGTCTCCTGAGGAGTTCACA GAAATAATGAACCAAAGAGAGCAATTCTACCATAAGGTGAATTTCTCCCCACCTGGTGAC ACAAACAGCCTTTTCCCAGGTACTTGGTACCTGGAGCGAGTGGACGAGCAGCATCGCCGA AAGTATGCCCGGCGTCCCGTCTAAAGGTGTTCTGCAGATCCATGGAAAGCTTCCTGGGAA ACGTATGCTAGCAGAGCTTCTCCCCGTGAATCATATTTTTAAGATCCCACTCTTAGCTGG TAAATGAATTTGAATCGACATAGTAGCCCCATAAGCATCAGCCCTGTAGAGTGAGGAGCC ATCTCTAGCGGGCCCTTCATTCCTCTCCATGCTGCAATCACTGTCCTGGGCTTATGGTGC TATGGACTAGGGGTCCTTTGTGAAAGAGCAAGATGGAGCAATGGAGAGAAGACCTCTTCC TGAATCACTGGACTCCAGAAATGTGCATGCAGATCAGCTGTTGCCTTCAAGATCCAGATA AACTTTCCTGTCATGTGTTAGAACTTTATTATTATTAATATTGTTAAACTTCTGTGCTGT TCCTGTGAATCTCCAAATTTTGTACCTTGTTTTAAGGCTAATATATAGCAATTAAAAAGA GAGAAAGAGGAAAAAAAAAAAAAAAAAACTCGA >OriGene 5' read for NM_005518 unedited
TTGTTTCANNATATTTGTNNAATACGACNCACTATAGGGCGGCCGCGAATTCGGCACGAG GCTGAACTGCTGGGTTTCTGCTTGCTCCTCTGGAGATGCAGCGTCTGTTGACTCCAGTGA AGCGCATTCTGCAACTGACAAGAGCGGTGCAGGAAACCTCCCTCACACCTGCTCGCCTGC TCCCAGTAGCCCACCAAAGGTTTTCTACAGCCTCTGCTGTCCCCCTGGCCAAAACAGATA CTTGGCCAAAGGACGTGGGCATCCTGGCCCTGGAGGTCTACTTCCCAGCCCAATATGTGG ACCAAACTGACCTGGAGAAGTATAACAATGTGGAAGCAGGAAAGTATACAGTGGGCTTGG GCCAGACCCGTATGGGCTTCTGCTCAGTCCAAGAGGACATCAACTCCCTGTGCCTGACGG TGGTGCAACGGCTGATGGAGCGCATACAGCTCCCATGGGACTCTGTGGGCAGGCTGGAAG TAGGCACTGAGACCATCATTGACAAGTCCAAAGCTGTCAAAACAGTGCTCATGGAACTCT TCCAGGATTCAGGCAATACTGATATTGAGGGCATAGATACCACCAATGCCTGCTACGGTG GTACTGCCTCCCTCTTCAATGCTGCCAACTGGATGGAGTCCAGTTCCTGNGATGGTCGTT ATGCCATGGTGGTCTGTGGAGACATTGCCGTCTATCCCAGTGGTAATGCTCGTCCCACAG GTGGGGCCGGAGCTGTGGCTATGCTGATTGGGCCCAAAGCCCCTCTGGCCCTGGAGCGAG GGCTGAAGGGAACCCATATGGAGAATGTGTATGACTTCTACAAACCAAATTTGGCCTCGG AGTACCCCATAGTGGATGGGAAGCTTTTCATCCAATGCTACCTGCCGGCCTTGGTATCGA GTTACACATATACCGGAAAAAT >OriGene 3' read for NM_005518 unedited
CGGCCGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTCCTCTTTCTCTCTTTTTAATT GCTATATATTAGCCTTAAAACAAGGTACAAAATTTGGAGATTCACAGGAACAGCACAGAA GTTTAACAATATTAATAATAATAAAGTTCTAACACATGACAGGAAAGTTTATCTGGATCT TGAAGGCAACAGCTGATCTGCATGCACATTTCTGGAGTCCAGTGATTCAGGAAGAGGTCT TCTCTCCATTGCTCCATCTTGCTCTTTCACAAAGGACCCCTAGTCCATAGCACCATAAGC CCAGGACAGTGATTGCAGCATGGAGAGGAATGAAGGGCCCGCTAGAGATGGCTCCTCACT CTACAGGGCTGATGCTTATGGGGCTACTATGTCGATTCAAATTCATTTACCAGCTAAGAG TGGGATCTTAAAAATATGATTCACGGGGAGAAGCTCTGCTAGCATACGTTCCCCAGGAAG CTTTCCATGGATCTGCAAAACACCTTTAGACGGGACGCCGGGCATACTTTCGGCGATGCT GTTCGTCCACTCGCTCCAGGTACCAAGTACCTGCGAAAAGGCTGTTTGTGCCACCACGTG GGCACAAATCCACCTTATGGTACAATTGCCCTCTTTGCGTCATTATTCCTGTGAACCCCT TACGAGACACCCACTTTTGGGAAGGCTCCGCGCCTCGCCAGGTCTCGAGTGCTTGGACAC CAACTCGATCAGGGGAGACCCTGGATCCATTCCTTGGCAACTTTAATGAACACAACCCCC CGTTCATCCCCCCACCATATATCCCTTTTCTCTGTCCCCCCCCCCCGCCTTATTTCCCCA TTATTTTGTCCTCTCTCCCCCGTTGAGCTTTCTTTCACCCTGCCCCCCCGTTCCGCTATT CCCCCCCCCCACTCTGCTTTTTGGCCACCCCCCCCCCCTCATTTTCCCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005518 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005518.2, NP_005509.1 |
| RefSeq Size | 2082 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 3158 |
| UniProt ID | P54868 |
| Domains | HMG_CoA_synt |
| Protein Families | Druggable Genome |
| Protein Pathways | Butanoate metabolism, Metabolic pathways, PPAR signaling pathway, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation |
| Gene Summary | The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] Transcript Variant: This variant (1) encodes the longer isoform (1). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208128 | HMGCS2 (Myc-DDK-tagged)-Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,784.00 |
|
| RC208128L3 | Lenti ORF clone of Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC208128L4 | Lenti ORF clone of Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 6,184.00 |
|
| RG208128 | HMGCS2 (tGFP-tagged) - Human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 5,384.00 |
